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Investigation of the Mechanistic Role and Translational Application of Btk to Target Ferroptosis Vulnerability in Drug-Tolerant Persister Esophageal Cancer

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

我們的初步研究已確定BTK為頑固型耐藥ESCC細胞在鐵死亡敏感性之調節因子, 這項研究將為靶向 BTK 作為靶向頑固性細胞的治療策略提供進一步證明,並優化 ESCC 患者對化療的治療反應。
StatusFinished
Effective start/end date8/1/237/31/24

Keywords

  • BTK
  • Drug-Tolerant Persister
  • Iron
  • Ferroptosis
  • ESCC
  • Esophageal Cancer