Investigating the Effects of Peripheral Ptx3 Blockade on Alzheimer'S Disease Therapy (Ii)

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

阿茲海默症為一種不可逆、進行性,神經退化性的疾病,目前並沒有特定藥物證明對其治療有效。本研究將利用PTX3單株抗體透過周邊免疫調節來達到改善中樞神經系統中,浸潤之免疫細胞族群與神經膠質細胞的功能,希望未來能以針對PTX3為標的來治療阿茲海默症。
StatusFinished
Effective start/end date8/1/227/31/23

Keywords

  • PTX3
  • systemic inflammation
  • peripheral-central immune regulation
  • microglia
  • Alzheimer’s disease