Identification of Targetable Mediators Involving in Pp1r15b Pathway to Overcome Resistance to Lenvatinib in Drug-Tolerant Persister Liver Cancer

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

本計畫研究結果為對頑固型耐藥休眠肝癌細胞提供更明確的分子機制,並開發新的肝癌診斷生物標記,提供新穎晚期肝癌治療靶點相關依據。
StatusFinished
Effective start/end date8/1/227/31/23

Keywords

  • Hepatocellular carcinoma
  • Lenvatinib-tolerant persister cell (LTPCs)
  • PPP1R15B-ATF4 axis