Genomic Epidemiology of Carbapenemase-Producing Klebsiella Pneumoniae in Taiwan: Population Structure, Transmission and Genetic Environments of Carbapenemases

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

抗後線抗生素(碳青黴烯類)肺炎克雷伯氏菌比例逐年上升,常引起醫療照護相關肺炎及血流感染,尤其是產生碳青黴烯酶肺炎克雷伯氏菌引起擔憂。本計畫將分析全國長期或單一家醫院所收集的產生碳青黴烯酶肺炎克雷伯氏菌,藉由基因體流行病學分析,預期可來了解台灣國內此菌的散播情況和來源,以及碳青黴烯酶遺傳環境,將對醫療場域內此類菌株感染的預防或阻斷提供參考依據。
StatusActive
Effective start/end date8/1/247/31/25

Keywords

  • arbapenem resistance
  • whole-genome sequencing
  • whole-genome multilocus sequence typing (wgMLST)
  • phylogenetics
  • plasmid
  • transposon