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Exosome-Based Novel Diagnosis of Disease Progress and Engineered Exosome-Based Novel Therapies against Ards-Induced Lung Injury and Fibrosis( II )

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

急性呼吸窘迫症候群(ARDS)有高致死率,其存活者亦會併發肺纖維化,迄今仍缺有效診斷及治療。本計畫將確認外泌體於診斷ARDS之可行性,並開發以工程化外泌體為基礎之ARDS創新治療模式。本計畫亦將確認非幹細胞之體細胞所得工程化外泌體療效,可望突破幹細胞取得不易之限制,促進使用非幹細胞之創新細胞治療發展。
StatusFinished
Effective start/end date8/1/247/31/25

Keywords

  • ARDS
  • lung injury
  • fibrosis
  • exosomes
  • liquid biopsy
  • exosome engineering
  • MSCs
  • THP-1
  • mice