Efficacy of Simvastatin in Renal Cell Carcinoma by Restraining Metabolic Reprogramming from Mtor, Ppar to Rhoa(1/3)

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Effective start/end date8/1/197/31/20


  • clear cell renal cell carcinoma (ccRCC)
  • the mammalian target of rapamycin (mTOR)
  • simvastatin
  • temsirolimus
  • rapamycin
  • PPARalpha
  • PPARgamma
  • RhoA
  • lipid deposition
  • migration
  • invasion
  • xenograft transplantation