Project Details
Description
透過循理化的藥物設計導入重要藥理基團和可穿透血腦障蔽官能基，架構多個系列的雙效抑制劑以達治療抗藥性多形性膠質母細胞瘤腦癌之臨床目的。
| Status | Finished |
|---|---|
| Effective start/end date | 8/1/22 → 7/31/23 |
Keywords
- Glioblastoma multiforme (GBM)
- prostaglandin-endoperoxide synthase 2 (Ptgs2)
- prostaglandin E2 receptor (EP) subtypes
- Dual inhibitors
- prodrug