Chinese prescriptions for external application in acne(2-2)

Specifically, evidence-based medicine appraises the quality of evidence gained from the scientific method to medical practice. Applying evidence-based medicine to traditional Chinese medicine (TCM) research would certainly enhance the clinical applicability. In this study, our objective is to systematically review the studies on herbal treatment for acne in order to find out the clinically effective herbal remedies and to use these remedies as lead drugs for the development of new treatment for acne treatment. Subproject planning for this study 1st year: systematic review of herbal remedies for acne treatment 2nd year: creating experimental models for assessment of the efficacies for acne treatment.In according to 1st year results, the most of TCMs are Ching-Shanp-Farng-Feng-Tang, Zen-Ren-Huo-Ming-Ying and Jia-Wei-Xiao-Yao-San from NHIRD. In the top ten TCMs, they all did not show anti-lipase activity, but Ching-Shanp-Farng-Feng- Tang and Zen-Ren-Huo-Ming-Ying both showed antibacterial and anti-inflammatory effects, Jia-Wei-Xiao-Yao-San did not. Therefore, Zen-Ren-Huo-Ming-Ying will be developed a new formulation to treat acne in 2nd year research.