Beta-3 Adrenergic Signaling on Ventricular Arrhythmogenesis: Insights from Cardiac Metabolism, Oxidative Stress and Ca2+ Homeostasis in Right Ventricular Outflow Tract Cardiomyocytes

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

若本研究能證實β3- 腎上腺接受體作用劑對心室細胞所引發的心律不整有關,可以深入探討心臟衰竭造成心律不整的機轉。若本計畫能順利執行,則有助於將來臨床上藥物研發、治療,或預防心臟衰竭引發的心律不整,可以改善國人的生活品質。
StatusFinished
Effective start/end date8/1/217/31/22

Keywords

  • RVOT
  • β3 agonist
  • sodium/calcium exchanger
  • mitochondrial function