Association between Polymorphisms of Thymidylate Synthase Gene and Clinical Outcome in Patients with Metastatic Colorectal Cancer Treated with 5-Fluorouracil-Based Chemotherapy

Medicine & Life Sciences

1. Thymidylate Synthase 100%
2. Fluorouracil 56%
3. Colorectal Neoplasms 46%
4. Drug Therapy 24%
5. Taiwan 16%
6. Haplotypes 15%
7. Genotype 11%
8. Population 9%
9. 3' Untranslated Regions 8%
10. Neoplasms 8%
11. Drug-Related Side Effects and Adverse Reactions 7%
12. Single Nucleotide Polymorphism 7%
13. Genes 6%
14. Cause of Death 6%
15. Retrospective Studies 5%
16. Prospective Studies 5%
17. Neoplasm Metastasis 5%