A Translational Exploration of Anisomelic Acid'S Potential in Reprogramming Tumor Immune Microenvironment (Time) to Overcome Immune Checkpoint Inhibitor (Ici) Resistance Mediated by Head and Neck Cancer Stem Cells

Project: A - Government Institution › b - National Science and Technology Council

Project Details

Description

Upon completing this study, we should obtain critical preclinical data supporting anisomelic acid's potential as a new cancer immunotherapeutic agent for HNSCC.
StatusActive
Effective start/end date8/1/24 → 7/31/25

Keywords

  • Head and neck squamous cell carcinomas (HNSCC)
  • cancer stem cells (CSCs)
  • suppressive tumor immune microenvironment (sTIME)
  • Immune checkpoint inhibitor (ICI)
  • M2 tumor-associated macrophages (M2 TAMs)
  • cancer-associated fibroblasts (CAFs)
  • anisomelic acid

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