A Preclinical Evaluation of a Niclosamide-based new small molecule, GBM_INT001 as an oncoimmune therapeutic agent targeting CDK4/DRD4/PD-L1 signature, for glioblastoma multiforme

Project: A - Government Institutionb - National Science and Technology Council

Project Details


Currently there is no effective treatment for most GBM patients. The development of GBM_INT001 may provide a new small-molecule drug for treating GBM. The successful completion of this project could lead to the promotion of local pharmacological industry, academic research and medical care system.
Effective start/end date8/1/217/31/22


  • Glioblastoma multiforme
  • Glioma stem cells
  • immunotherapy
  • new drug development


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