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  Natural Product Research Combining Precision Instruments, Database and Docking Technology-Application and Problem Solving of Plant Metabolites

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Therapeutic Potential and Molecular Mechanism of Natural Products in Pediatric High-Grade Gliomas

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展一新型藥物作為改善肥胖及肥胖引發糖尿病導致腎病變症候群之轉譯醫學研究(3/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立探討膜蛋白折疊的研究平台(3/3)

  Chang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Npff/Npffr2 on the Modulation of Metabolic Health: from Central to Peripheral System

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Microplastics and Nanoplastics Exposure Induce Autophagy and Upregulate Srebps in Kidneys and Cause Endothelial Leakiness in Blood Vessels

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of ARCS model of motivation and experiential learning theory in Gerontological Nursing course

  Chuang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(1/3)

  Feng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Integrated Proteomic,Genetic,Small-Molecule, and Functional Screening of Novel and Targetable Invadopodial Regulators in Stem-Like Cancer Cells: Focusing on Cell-Surface Amfr as a Prioritized Therapeutic Target in Invasive Gastroenterological Cancers( II )

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of the Hdacs/Sp1-Mediated Microrna-106b~25 Axis in Drug Resistance of Glioblastomas( III )

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Classification of Endometrial Cancer by Bhlhe22 Subtypes in Normal Endometrium

  Liew, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以資料探勘技術進行大數據分析，建立術中低血氧與術後休克風險預測模型(2/2)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Deep Learning to Improve Cerebrovascular Reserve Measurement from Baseline Mri

  Chen, D. C. & Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Associations of Intestinal Microflora, Food and Fat Metabolites, and Liver and Brain Function Degradation Induced by a Long-Term High-Fat Dietary Pattern

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構空氣汙染物、易感受性基因及傳統危險因子對於缺血性中風風險之個人化精準預測模式(3/3)

  Chiou, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食安風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑對青春期早發育的影響及相關機轉探討(2/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Application of Α9 Nicotine Receptor Gene Expression in Circulating Blood Tumor Cells / Cell Free Dna of Breast Cancer Patients for Breast Cancer Treatment( II )

  Tzeng, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在動物模式下發展穿顱干擾波電刺激新技術應用於中風膀胱功能障礙復健治療(2/3)

  Peng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺阻塞表型分析與治療策略(1/3)

  Tseng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 分析非典型趨化因子CCRL2 在癌症細胞器官專一性轉移及粒線體呼吸鏈上所扮演之角色

  Sung, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 滑世代幼兒期親子睡眠與晝夜節律追蹤研究-整合智慧型資料探討3C產品使用與孕產期相關因子影響效應(3/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非營養性甜味劑對生殖系統之影響及可能作用機轉:從青春期到懷孕期-婦女攝取非營養性甜味劑對懷孕狀況之影響(2/3)

  Hsieh, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過非監督式微生物群基因體分類工具深度挖掘與分析微生物如何影響疾病的產生(1/3)

  Wu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 金屬細懸浮微粒在慢性阻塞性肺病的第二型肺泡上皮細胞Yap/Taz調控衰老機轉之研究(2/3)

  Chuang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用機器學習演算法透過基因體資訊挖掘未知基因的功能與預測細菌抗藥性(3/3)

  Wu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討甜味受體在調控血糖衡定所扮演的角色(1/3)

  Wu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 以虛擬實境方式強化[食品法規與管理]的實務應用教學

  Yang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 新穎性結構天然物萘醌衍生物於血管及淋巴管新生抑制與抗腫瘤之應用及其機轉探討(2/3)

  Huang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 副甲狀腺素藉由SFRP2導致動靜脈廔管病變之惡化 – 預防動靜脈廔管不成熟之新治療標的 (第二年延續計畫)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Elucidate the mechanisms, development and effectiveness of balance control and gait strategy after mild traumatic brain injury: develop innovative design of computerized dual-task balance module and precision treatment of transcranial magnetic stimulation

  Lin, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米控釋介導間質幹細胞外泌體合併細胞激素結合誘餌胜?與微囊蛋白-1支架領域胜?之三功能協同創新療法於治療肥胖併發敗血症所致器官傷害與死亡之療效: 聚焦細胞死亡相關機轉(1/2)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Creating a dementia-friendly environment - Virtual Reality Program to promote college students' empathy and knowledge toward dementia

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• Effects of Visfatin on Proliferative and Microenvironment of Uterine Leiomyoma: Molecular Mechanism and Application of Precision Nutrition( II )

  Hsia, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以電混凝浮除法同時處理火力發電廠廢水中硼與硝酸鹽之研究(2/3)

  Hu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用單細胞定序技術進行細胞轉錄組及表位標誌來解構腎臟損傷,復原及纖維化過程中腎臟單細胞核吞噬細胞系統的角色(1/3)

  Liao, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 後疫時代數位病理學課程建構與線上學習學生接受度學習成效分析

  Chu, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 探討發酵米糠之補充對腸道菌生態及腸道黏膜免疫系統之芳香烴受體路徑之影響：以葡聚糖硫酸鈉引致之腸炎小鼠為模式(2/3)

  Yeh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A multi-modal investigation of the relationship between dopamine-serotonin signaling and intrinsic brain activity in bipolar disorder (1/3)

  Magioncalda , P.

  8/1/21 → 10/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(2/3)

  Lu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Arachidonate Metabolism in Determining Ying-Yang Effects of Sp1 on Drug Resistance in Glioblastoma and Lung Cancer( III )

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Basic and Translational Study of the Neuronal Functions of Tdp-43 Protein and Its Dysfunction in Neurodegenerative Diseases( III )

  Shen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Clinical Prediction and Pathogenesis Pathway Discovery to Prevent Idiopathic Pregnancy Diseases by Deep Learning Algorithms on Multi-Country Databases( I )

  Su, E. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Role of Arnt/Pdk1 Axis in Chemotherapy-Associated Progression of Head and Neck Squamous Cell Carcinoma( II )

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Emerging Impact of Gut Microbiota-Gut Metabolite-Host Posttranscriptional Event Network on Manipulating Gut Homeostasis or Carcinogenic Signature of Colorectal Cancer Cells

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(3/3)

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Explore the Pathophysiology Role of Vascular Endothelial Cell and Adam 17 during Blue Light-Induced Retinopathy, and the Therapeutic Strategy

  Li, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Survival and Invasiveness of Prostate Cancer Post Modulation of Mitochondrial Dynamics and Metabolism Modulated by Pgc1α/Sirt3/Etc Complexes-Assessment of the Strategy Utilizing Sirt3 Regulator to Attenuate Chemoresistance

  Peng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-基於整合素αvβ3和CEACAM6的訊號網絡建立膽管癌患者的診斷生物標記與治療標靶之臨床連結(1/3)

  Whang-Peng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Breakthrough Therapeutic Strategy against Ischemic Brain Injury- the Senolytic Treatment Dramatically Expands Therapeutic Time Window of Acute Ischemic Stroke

  Hsieh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology