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  CXCL5/CXCR2/JNK Axis Is the Shared Pathway of Neuroinflammation and Microvascular Damage That Contributes to White Matter Injury in the Immature Brain

  Huang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)

  Juan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration

  Tseng, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Mechanisms of SSRI Antidepressants and GABAAR Modulators Inhibit High-Grade Glioma Invasion

  Shen, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women.

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Applications of Α-Galactosylceramide-Incorporated Liposome as a Targeting Antigen Carrier for Cancer Vaccine Therapy

  Liu, D.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploration of RBM4-Regulated Splicing Events in Differentiating Adipocytes by Using Next-Generation Sequencing

  Lin, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Arsenic Methylation Capacity, Methylenetetrahydrofolate Reductase and Dna Methylation Gene Polymorphisms, Plasma Selenium Concentration and Selenoprotein Gene Polymorphisms and Renal Cell Carcinoma

  Hsueh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• ALA Photodynamic Therapy, Tumor Hypoxia, CSE1L Phosphorylation, and the Progression and Treatment of Skin Cancer

  Lee, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Mechanistic Action of DDX3 in Colorectal Tumor Progression

  Lee, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(3/3)

  Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Epidemiological Study of Renal Cell Carcinoma---Arsenic Methylation Capability, 8-OHdG and Polymorphism of IRS and RAAS Exploration

  Hsueh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Natural Product Hybrid and Ortho-Biaryl N-Hydroxycinnamide as Leads for Anticancer Agent Development

  Huang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Transcriptional and Epigenetic Mechanisms for the Nm23-H1 Expression---An Nm23-H1-Promoter Screening Platform for Novel Metastasis-Suppressing Anticancer Drugs

  Wang, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Promoting Healthy Eating---A Family-Centered Obesity Prevention Randomized Control Trial for Preschool Children

  Chang, P.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• MicroRNA-184在肺腫瘤化和臨床預後之角色

  Lee, H.

  8/1/14 → 7/31/15

  Project: C - Project of Alliance › r - Tung's Taichung MetroHarbor Hospital

• Emerging Mechanisms of Omega-3 Fatty Acids in Depression---The Effects of EPA and DHA on Chronic Stress, Neurogenesis and Neuroinflammation

  Huang, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats

  Peng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on Dental Implant Stability Detection Using Damping Factor as a Parameter

  Huang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Functional Electrical Stimulation Cycling and Central Neuromodulation on Motor Control in Stroke

  Chen, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Indoor Air Quality Improvement on Cardiovascular Health in General Population

  Chuang, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Hyaluronic Acid and Resveratrol Modified Carbon Nanotube Scaffolds for Tissue Engineering

  Sheu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of a Program of Mind-Body Interventions on Psychological Resilience, Vagal Tone, Emotional States, and Outcomes of Heart Failure

  Tsai, P.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring the Effects of an Exercise Program on Female Diabetic Patients' Health

  Liao, Y.

  8/1/14 → 8/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Health Risk Behaviors on Recurrent Traffic Injury

  Chen, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Functional Studies of ZNF179 in Neurons in vitro and in vvo

  Lee, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Association between Lipid, Glucose Related Genes and Prognosis of Intra- and Extra-Cranial Stenosis in Stroke Patients

  Chiou, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Red-Light Violations by Traditional/Electric Motorcycles/Bicycles: An Observational Field Study of Risk-Taking, Opportunistic, and Law-Obeying Behaviours

  Pai, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (III)

  Lin, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Spatiotemporal Analysis of the Effects of Ambient Bioparticles on Allergic Diseases in the Greater Taipei Area

  Chao, H. J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building a Cancer Progress Model Based on PPI Network and Gene Expression Changes and Its Applications for Classification of Cancer Subtypes

  Chiu, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• https://www.grb.gov.tw/search/planDetail?id=8356932&docId=447412

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on the Suppressive Mechanisms of Novel Anti-Glypican3 Antibody Drugs

  Yang, Y.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke---Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging (III)

  Chen, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents

  Liou, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the Role of Glucosed-Regulated Portein 78 in the Progression, Metastasis and Therapy of Colorectal Cancer

  Wei, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on Combination of Hydrophobic Anticancer Drugs Encapsulated in Nanocarriers and Hydrophilic Anticancer Drugs Loaded in Thermosensitive Hydrogels into Cancer Cell

  Ho, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• An Association Study of Mitochondrial Function Related Genes and Ischemic Stroke

  Hsieh, F.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Evaluation of the Long-Term Effects of Interpersonal and Social Rhythm Therapy on Sleep and Social Functioning in Patients with Bipolar Disorder

  Chung, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluate the Radio-Biological Roles of miR-17-5P in Oral Cancer Cell Line OC3

  Wu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Oncolytic Measles Virus for the Treatment of Breast Adenocarcinoma

  Lin, L. T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chen, R.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impact of Functional Connectivity MR Imaging Study in the Correlation of the Surgical Outcome Validations and Neuroplasticity of Lumbar Spinal Stenosis with Neurogenic Intermittent Claudication

  Huang, T.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma---The Treatment of Metastatic Cancer

  Chien, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology