Personal profile
Education
- 2012 Ph.D., Institute of Basic Medical Sciences, National Cheng Kung University
- 2006 M.S., Institute of Molecular Medicine, National Cheng Kung University
- 2004 B.S., Department of Food and Nutrition, Chinese Culture University
Experience
- 2024.02- Director, Core Laboratory of Good Tissue Practice (GTP), Taipei Medical University, Taipei, Taiwan
- 2019.07- Assistant Research Fellow, TMU Research Center of Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan
- 2019.07-2024.01 Quality Control Manager, Core Laboratory of Good Tissue Practice (GTP), Taipei Medical University, Taipei, Taiwan
- 2018.08-2019.06 Postdoctoral Researcher School of Traditional Chinese Medicine, Chang Gung University, Taoyuan City, Taiwan
- 2016.01-2018.07 Postdoctoral Researcher TMU Research Center of Cell Therapy and Regeneration Medicine, Taipei Medical University, Taipei, Taiwan
- 2014.08-2018.07 Postdoctoral Fellow Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
- 2013.09-2014.08 Postdoctoral Fellow Graduate Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan
- 2012.10-2013.08 Second Lieutenant Taichung Armed Forces General Hospital, Taichung, Taiwan
Awards
- 2024 The 21th National Innovation Award - Academic Research Category
- 2022 National Innovation Award - Excelsior Award
- 2021 The 18th National Innovation Award - Academic Research Category
- 2017 Excellent Performance Award, International Conference of Developmental Biology, Stem Cells and Regenerative Medicine
- 2015 Poster Competition Award, International Conference on Stem Cells and Developmental Biology
- 2014-2018 Outstanding Postdoctoral Researcher Award, Taipei Medical University, Taiwan
- 2006-2008 PhD Scholarship Award, National Cheng Kung University, Taiwan
Research Interests
- Cell Therapy
- Stem Cell Biology / Regenerative Medicine
- Tumor Biology
- Reproductive Biology
- Molecular and Cell Biology
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Collaborations and top research areas from the last five years
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Regulation of Pluripotency in Germline Stem Cells: the Effect of Crosstalk between Satb2, Igf-1r, and Laminin Niches on Cell Fate Determination (Continuous Proposal)
Kuo, Y. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Regulation of Pluripotency in Germline Stem Cells: the Effect of Crosstalk between Satb2, Igf-1r, and Laminin Niches on Cell Fate Determination (Continuous Proposal)
Kuo, Y. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Regulation of Pluripotency in Germline Stem Cells: the Effect of Crosstalk between Satb2, Igf-1r, and Laminin Niches on Cell Fate Determination
Kuo, Y. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Regulation of Pluripotency in Germline Stem Cells: the Effect of Crosstalk between Satb2, Igf-1r, and Laminin Niches on Cell Fate Determination
Kuo, Y. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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探討Lenvatinib合併使用IGF-1R抑制劑 Linsitinib逆轉抗Sorafenib肝癌抗藥性的機制
Kuo, Y. (PI)
7/1/22 → 2/28/23
Project: A - Government Institution › b - National Science and Technology Council
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HBV X protein regulates cancer stemness and tumor invasiveness through SENP1 in hepatocellular carcinoma
Wu, Y. C., Huang, Y. C., Kuo, Y. C., Ngo, M. H. T., Lee, K. F., Sung, Y. T., Wang, H. F., Doong, S. L., Kuo, L. M., Chang, T. S. & Huang, Y. H., Jan 2026, In: JHEP Reports. 8, 1, 101620.Research output: Contribution to journal › Article › peer-review
Open Access -
Double-sided niche regulation in skin stem cell and cancer: mechanisms and clinical applications
Pham, T. T. Q., Kuo, Y. C., Chang, W. L., Weng, H. J. & Huang, Y. H., Dec 2025, In: Molecular Cancer. 24, 1, 147.Research output: Contribution to journal › Review article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Nicotine-driven enhancement of tumor malignancy in triple-negative breast cancer via additive regulation of CHRNA9 and IGF1R
Kuo, Y. C., Chen, C. L., Lee, K. L., Wang, H. F., Drew, V. J., Lan, P. C., Ho, Y. S. & Huang, Y. H., Jun 2025, In: Journal of Pathology. 266, 2, p. 230-245 16 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Citations (Scopus) -
Secretome from human placenta-derived mesenchymal stem cells repairs mechanically induced meniscus injury in mice by activating the proliferation and suppressing the apoptosis of endogenous meniscus progenitor cells
Chen, W. H., Lai, W. Y., Le, D. C., Hsing, J. C., Ngo, M. H. T., Kao, C. X., Fan, K. Y., Lin, G. W., Ling, T. Y., Kuo, Y. C. & Huang, Y. H., Dec 2025, In: Stem Cell Research and Therapy. 16, 1, 565.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel SEPT12 mutation, T96I, is associated with sperm head and annulus defects
Chen, K. R., Wang, H. Y., Kuo, Y. C., Lo, Y. C. & Kuo, P. L., 2024, In: Frontiers in Cell and Developmental Biology. 12, 1498013.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus)
Datasets
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MOESM1 of DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation
Lai, S.-C. (Contributor), Wu, Y.-C. (Contributor), Chi, C.-C. (Contributor), Lan, P.-C. (Contributor), Lee, K.-F. (Contributor), Yang, M.-H. (Contributor), Su, Y.-T. (Creator), Chang, T.-S. (Contributor), Kuo, Y.-C. (Contributor) & Huang, Y.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.11273585.v1, https://doi.org/10.6084%2Fm9.figshare.11273585.v1
Dataset
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Transcriptome expression pattern of E11.5 PGCs, P2 GSCs, and CD49f+GSCs.
Kuo, Y.-C. (Contributor) & Huang, Y.-H. (Contributor), Gene Expression Omnibus, 2017
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106664
Dataset