Projects per year
Personal profile
Education
- 1988 Ph.D. (Pathology and Cell Biology), Thomas Jefferson University, Philadelphia
- 1982 M.D., Taipei Medical College, Taipei, Taiwan
Experience
- 2017-2022 Director, Research Center of Cancer Translational Medicine, Taipei Medical University
- 2011- Professor, Taipei Medical University
- 2011-2017 President, Taipei Medical University
Affiliate Professor, California Institute of Technology, Pasadena, CA
Chair, The Chinese Oncology Society
Chair, ASCO International Affair Community
Chair, Molecular Pharmacology Department, City of Hope
Associate Director for Translational Research, City of Hope Comprehensive Cancer Center
Adjunct Professor, School of Pharmacy, University of Southern California
Adjunct Professor, Graduate Institute of Oncology, College of Medicine, National Taiwan University
Awards
- Academician, International Academy of Engineering, Russia
- Fellow, American Association for the Advancement of Science(AAAS)
- Tang Prize Board Member
- Board of Trustees, NHRI (Taiwan NIH), Taiwan
- Kuong-Chi Scholar, Zhejiang University, Hangzhou, China
- Steering Committee of Ming Hsieh Institute, USA
- Who’s Who International and Professional Member (life member)
- America’s Top Doctor (life member)
- Hedvig Foundation Award
- Cooper Portrait for Scientific Achievement Award in Cooper Auditorium, City of Hope
- Distinguished Alumnus Award, Thomas Jefferson University, Philadelphia
Research Interests
- Cancer Research
- Translational Medicine
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Collaborations and top research areas from the last five years
Projects
- 47 Finished
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111年度高等教育深耕計畫第2部分-特色領域研究中心計畫
Yen, Y. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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2-1-1 發展居國際領先地位之研究領域-癌症轉譯研究中心業務費
Yen, Y. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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110年度高等教育深耕計畫第2部分-特色領域研究中心計畫
Yen, Y. (PI)
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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以α9-尼古丁受體作為分子標靶探討國人乳癌發生之風險暴露及抗體藥物研發與臨床前試驗評估(第4年)
Yen, Y. (PI)
1/1/21 → 12/31/21
Project: A - Government Institution › c - Ministry of Health and Welfare
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2-1-1 發展居國際領先地位之研究領域-癌症轉譯研究中心業務費
Yen, Y. (PI)
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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Photobiomodulation and extracellular vesicles-loaded alginate from adipose mesenchymal stem cells for cartilage repair in a rat model of osteoarthritis
Hang, N. L. T., Wong, C. C., Chen, Y. T., Tseng, Y. W., Cheng-Jen-Chang, Yen, Y., Yang, T. S. & Chuang, A. E. Y., Jul 2026, In: International Journal of Biological Macromolecules. 371, 152996.Research output: Contribution to journal › Article › peer-review
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Source-Specific Photobiomodulation Regulates Mitochondrial Bioenergetics, Redox Signaling, and Functional Outputs in C2C12 Myoblasts Across Replicative Aging
Aviña, A. E., Hang, N. L. T., Chang, C. Y., Chen, Y. F., Yen, Y., Wong, X. P. C., Wang, A. Y. L., Chang, C. J. & Yang, T. S., Apr 2026, In: International journal of molecular sciences. 27, 7, 2999.Research output: Contribution to journal › Article › peer-review
Open Access -
A method to validate viral copy-number assay involving a hybrid amplicon and duplex droplet digital PCR
Wu, R., Luh, F., Kweon, S. M. & Yen, Y., Jun 12 2025, In: Molecular Therapy Methods and Clinical Development. 33, 2, 101483.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Correction to: Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients (Biomarker Research, (2025), 13, 1, (7), 10.1186/s40364-024-00715-5)
Cheng, T. C., Hung, M. C., Wang, L. H., Tu, S. H., Wu, C. H., Yen, Y., Chen, C. L., Whang-Peng, J., Lee, W. J., Liao, Y. C., Lee, Y. C., Pan, M. H., Lin, H. K., Tzeng, H. E., Guo, P., Chu, C. Y., Chen, L. C. & Ho, Y. S., Dec 2025, In: Biomarker Research. 13, 1, 100.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
FGFR inhibitors promote the autophagic degradation of IFN-γ-induced PD-L1 and alleviate the PD-L1-mediated transcriptional suppression of FGFR3-TACC3 in non-muscle-invasive bladder cancer
Lin, Y. C., Chu, C. Y., Hsieh, T. H., Lin, B. J., Liou, J. P., Yen, Y. & Chen, C. H., Dec 2025, In: Cell Death and Disease. 16, 1, 485.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Citations (Scopus)
Datasets
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Additional file 1: Figure S2. of Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Whang-Peng, J. (Creator), Yen, Y. (Creator), Huang, Y.-J. (Contributor), Yang, C.-K. (Contributor), Tzeng, Y.-M. (Contributor), Meng, T.-C. (Contributor), Wu, A. T. (Creator), Wei, P.-L. (Contributor), Huynh, T.-T. (Contributor) & Hsiao, M. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533_d2.v1
Dataset
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Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Huang, Y.-J. (Contributor), Yang, C.-K. (Contributor), Wei, P.-L. (Contributor), Huynh, T.-T. (Contributor), Whang-Peng, J. (Creator), Meng, T.-C. (Contributor), Hsiao, M. (Creator), Tzeng, Y.-M. (Contributor), Wu, A. T. (Creator) & Yen, Y. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533.v1
Dataset
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Additional file 2: Figure S1. of Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Huynh, T.-T. (Contributor), Tzeng, Y.-M. (Contributor), Yen, Y. (Creator), Yang, C.-K. (Contributor), Wu, A. T. (Creator), Meng, T.-C. (Contributor), Whang-Peng, J. (Creator), Wei, P.-L. (Contributor), Hsiao, M. (Creator) & Huang, Y.-J. (Contributor), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533_d1.v1
Dataset
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MOESM1 of Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers
Chen, Y.-F. (Contributor), Wang, Y.-H. (Contributor), Lei, C.-S. (Contributor), Changou, C. (Contributor), Davis, M. (Contributor) & Yen, Y. (Contributor), Unknown Publisher, Jan 1 2019
DOI: 10.6084/m9.figshare.10033625.v1, https://springernature.figshare.com/articles/MOESM1_of_Host_immune_response_to_anti-cancer_camptothecin_conjugated_cyclodextrin-based_polymers/10033625/1
Dataset
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The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair
Zhou, B. (Contributor), Zhang, K. (Contributor), Un, F. (Contributor), Hu, S. (Contributor), Wu, J. (Contributor), Wang, Y. (Contributor), Liu, X. (Contributor), Li, H. (Contributor), Liu, Z. (Contributor), Su, L. (Contributor) & Yen, Y. (Contributor), ArrayExpress, 2015
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55004
Dataset