Projects per year
Personal profile
Education
- 1988 Ph.D. (Pathology and Cell Biology), Thomas Jefferson University, Philadelphia
- 1982 M.D., Taipei Medical College, Taipei, Taiwan
Experience
- 2017-2022 Director, Research Center of Cancer Translational Medicine, Taipei Medical University
- 2011- Professor, Taipei Medical University
- 2011-2017 President, Taipei Medical University
Affiliate Professor, California Institute of Technology, Pasadena, CA
Chair, The Chinese Oncology Society
Chair, ASCO International Affair Community
Chair, Molecular Pharmacology Department, City of Hope
Associate Director for Translational Research, City of Hope Comprehensive Cancer Center
Adjunct Professor, School of Pharmacy, University of Southern California
Adjunct Professor, Graduate Institute of Oncology, College of Medicine, National Taiwan University
Awards
- Academician, International Academy of Engineering, Russia
- Fellow, American Association for the Advancement of Science(AAAS)
- Tang Prize Board Member
- Board of Trustees, NHRI (Taiwan NIH), Taiwan
- Kuong-Chi Scholar, Zhejiang University, Hangzhou, China
- Steering Committee of Ming Hsieh Institute, USA
- Who’s Who International and Professional Member (life member)
- America’s Top Doctor (life member)
- Hedvig Foundation Award
- Cooper Portrait for Scientific Achievement Award in Cooper Auditorium, City of Hope
- Distinguished Alumnus Award, Thomas Jefferson University, Philadelphia
Research Interests
- Cancer Research
- Translational Medicine
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Collaborations and top research areas from the last five years
Projects
- 47 Finished
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2-1-1 發展居國際領先地位之研究領域-癌症轉譯研究中心業務費
Yen, Y. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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111年度高等教育深耕計畫第2部分-特色領域研究中心計畫
Yen, Y. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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以α9-尼古丁受體作為分子標靶探討國人乳癌發生之風險暴露及抗體藥物研發與臨床前試驗評估(第4年)
Yen, Y. (PI)
1/1/21 → 12/31/21
Project: A - Government Institution › c - Ministry of Health and Welfare
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2-1-1 發展居國際領先地位之研究領域-癌症轉譯研究中心業務費
Yen, Y. (PI)
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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110年度高等教育深耕計畫第2部分-特色領域研究中心計畫
Yen, Y. (PI)
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients
Cheng, T.-C., Hung, M.-C., Wang, L.-H., Tu, S.-H., Wu, C.-H., Yen, Y., Chen, C.-L., Whang-Peng, J., Lee, W.-J., Liao, Y.-C., Lee, Y.-C., Pan, M.-H., Lin, H.-K., Tzeng, H.-E., Guo, P., Chu, C.-Y. & Chen, L.-C., Jan 9 2025, In: Biomarker Research. 13, 1, p. 7Research output: Contribution to journal › Article › peer-review
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A new potential therapeutic approach for ALS: A case report with NGS analysis
Hu, C. J., Chen, P. C., Padmanabhan, N., Zahn, A., Ho, C. M., Wang, K. & Yen, Y., Mar 1 2024, In: Medicine (United States). 103, 9, p. E37401Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Exosomes: a review of biologic function, diagnostic and targeted therapy applications, and clinical trials
Chen, Y. F., Luh, F., Ho, Y. S. & Yen, Y., Dec 2024, In: Journal of Biomedical Science. 31, 1, 67.Research output: Contribution to journal › Review article › peer-review
Open Access14 Citations (Scopus) -
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes
Chen, Z., Guo, X., Tao, R., Huyghe, J. R., Law, P. J., Fernandez-Rozadilla, C., Ping, J., Jia, G., Long, J., Li, C., Shen, Q., Xie, Y., Timofeeva, M. N., Thomas, M., Schmit, S. L., Díez-Obrero, V., Devall, M., Moratalla-Navarro, F., Fernandez-Tajes, J. & Palles, C. & 185 others, , Dec 2024, In: Nature Communications. 15, 1, 3557.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Investigation of the α9-nicotinic receptor single nucleotide polymorphisms induced oncogenic properties and molecular mechanisms in breast cancer
Liao, Y. C., Wang, L. H., Hung, M. C., Cheng, T. C., Lin, Y. C., Chang, J., Tu, S. H., Wu, C. H., Yen, Y., Hsieh, Y. C., Chen, L. C. & Ho, Y. S., Nov 8 2024, In: Human Molecular Genetics. 33, 22, p. 1948-1965 18 p.Research output: Contribution to journal › Article › peer-review
Datasets
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The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair
Zhou, B. (Contributor), Zhang, K. (Contributor), Un, F. (Contributor), Hu, S. (Contributor), Wu, J. (Contributor), Wang, Y. (Contributor), Liu, X. (Contributor), Li, H. (Contributor), Liu, Z. (Contributor), Su, L. (Contributor) & Yen, Y. (Contributor), ArrayExpress, 2015
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-55004
Dataset
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Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Huang, Y.-J. (Contributor), Yang, C.-K. (Contributor), Wei, P.-L. (Contributor), Huynh, T.-T. (Contributor), Whang-Peng, J. (Creator), Meng, T.-C. (Contributor), Hsiao, M. (Creator), Tzeng, Y.-M. (Contributor), Wu, A. T. (Creator) & Yen, Y. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533.v1
Dataset
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Additional file 1: Figure S2. of Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Whang-Peng, J. (Creator), Yen, Y. (Creator), Huang, Y.-J. (Contributor), Yang, C.-K. (Contributor), Tzeng, Y.-M. (Contributor), Meng, T.-C. (Contributor), Wu, A. T. (Creator), Wei, P.-L. (Contributor), Huynh, T.-T. (Contributor) & Hsiao, M. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533_d2.v1
Dataset
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Characterization of Gene Expression in ASS1-Deficient Breast Cancer Cells
Qiu, F. (Contributor), Liu, X. (Contributor), Xu, J. (Contributor), Gaur, S. (Contributor), Zhang, H. (Contributor), Zheng, S. (Contributor), Yen, Y. (Contributor) & Huang, J. (Contributor), ArrayExpress, 2014
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-53838
Dataset
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Additional file 2: Figure S1. of Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Huynh, T.-T. (Contributor), Tzeng, Y.-M. (Contributor), Yen, Y. (Creator), Yang, C.-K. (Contributor), Wu, A. T. (Creator), Meng, T.-C. (Contributor), Whang-Peng, J. (Creator), Wei, P.-L. (Contributor), Hsiao, M. (Creator) & Huang, Y.-J. (Contributor), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533_d1.v1
Dataset