Projects per year
Personal profile
Education
- 2007 Ph.D. Graduate Institute of Pharmacognosy, Taipei Medical University
- 1999 M.S., School of Pharmacy, College of Medicine, Taipei Medical University
- 1993-1997 B.S., Department of Medical Laboratory Science and Biotechnology, Taipei Medical University
Experience
- 2021.02- Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2018.02-2021.01 Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2018.01-2014.07 Postdoctoral Researcher, Institute of Biological Chemistry, Academia Sinica
- 2014.09-2018.01 Assistant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
Awards
- 2015 Visiting Scholars, Genomics Research Center, Academia Sinica, Taiwan
- 2015 Reviewer for PLoS one
- 2008, 2009 and 2013 Reviewer for Journal of Cellular Biochemistry
Research Interests
- Cancer Drug Discovery
- Protein-Protein Interaction
Related Link
Fingerprint
Dive into the research topics where Yuan-Feng Lin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigating the Molecular Mechanism in Which Disrupting the Protein-Protein Interactions of Hsp27 Selectively Kills Triple-Negative Breast Cancer and Developing the New Hsp27-Targeted Anti-Cancer Drugs
Lin, Y.-F. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Studying on the Molecular Mechanism in Which Gbp5 Utilizes Inflammasome to Construct a Nf-Κb-Dependent Feedback Looping and Thereby Promotes Therapeutic Resistance, Metastasis and Immunosuppression in Oral Squamous Cell Carcinoma
Lin, Y.-F. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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探討AEBP1在促進多形性膠質母細胞瘤之 temozolomide抗藥性中的角色
Lin, Y.-F. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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利用Iodoacetamide衍生物找尋與鑑定新型藥物標靶用於治療多型性神經膠質母細胞瘤
Lin, Y.-F. (PI)
7/1/22 → 2/28/23
Project: A - Government Institution › b - National Science and Technology Council
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Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer
Lin, Y.-F. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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The IL-8/NF-κB feedback loop confers a paclitaxel-sensitive/doxorubicin-resistant phenotype in triple-negative breast cancer
Lin, H. Y., Wang, W. K., Lin, C. H., Kuei, C. H., Lee, H. H., Kent Lin, Y. H., Chiu, H. W. & Lin, Y. F., Oct 2025, In: Free Radical Biology and Medicine. 238, p. 316-328 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma
Chiu, H. W., Lee, H. L., Lee, H. H., Lu, H. W., Lin, K. Y. H., Lin, Y. F. & Lin, C. H., Dec 2024, In: Journal of Translational Medicine. 22, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis
Wang, W. K., Lin, H. Y., Lin, C. H., Lee, H. H., Chen, Y. L., Lin, Y. H. K., Chiu, H. W., Sheen-Chen, S. M. & Lin, Y. F., Dec 2024, In: Breast Cancer Research. 26, 1, 193.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Guanylate binding protein 5 triggers NF-κB activation to foster radioresistance, metastatic progression and PD-L1 expression in oral squamous cell carcinoma
Chiu, H. W., Lin, C. H., Lee, H. H., Lu, H. W., Lin, Y. H. K., Lin, Y. F. & Lee, H. L., Feb 2024, In: Clinical Immunology. 259, 109892.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
AIM2 upregulation promotes metastatic progression and PD-L1 expression in lung adenocarcinoma
Zheng, J. Q., Lin, C. H., Lee, H. H., Chang, W. M., Li, L. J., Su, C. Y., Lee, K. Y., Chiu, H. W. & Lin, Y. F., Jan 2023, In: Cancer Science. 114, 1, p. 306-320 15 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (Scopus)
Datasets
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Additional file 1: Table S1. of Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, W.-M. (Creator), Hsiao, M. (Creator), Su, C.-Y. (Contributor), Chang, P.M.-H. (Creator), Lin, Y.-F. (Contributor), Wu, A. T. H. (Creator), Chen, C.-L. (Creator), Chi, L.-H. (Contributor), Chen, M.-H. (Creator) & Chang, Y.-C. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3660368_d1.v1
Dataset
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Additional file 1: of Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Huang, M.-S. (Contributor), Jan, Y.-H. (Creator), Yang, C.-J. (Contributor), Hsiao, M. (Creator), Lin, Y.-F. (Creator) & Lai, T.-C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.7648181.v1, https://doi.org/10.6084%2Fm9.figshare.7648181.v1
Dataset
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Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Jan, Y.-H. (Creator), Lai, T.-C. (Contributor), Yang, C.-J. (Contributor), Lin, Y.-F. (Creator), Huang, M.-S. (Contributor) & Hsiao, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4383008.v1, https://doi.org/10.6084%2Fm9.figshare.c.4383008.v1
Dataset
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Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, Y.-C. (Creator), Chi, L.-H. (Contributor), Chang, W.-M. (Creator), Su, C.-Y. (Contributor), Lin, Y.-F. (Contributor), Chen, C.-L. (Creator), Chen, M.-H. (Creator), Chang, P.M.-H. (Creator), Wu, A. T. H. (Creator) & Hsiao, M. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368.v1, https://figshare.com/collections/Glucose_transporter_4_promotes_head_and_neck_squamous_cell_carcinoma_metastasis_through_the_TRIM24-DDX58_axis/3660368/1
Dataset
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The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
Huang, S.-P. (Contributor), Liu, P.-Y. (Contributor), Kuo, C.-J. (Contributor), Chen, C.-L. (Contributor), Lee, W.-J. (Contributor), Tsai, Y.-H. (Creator) & Lin, Y.-F. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3794620.v1, https://figshare.com/collections/The_G_h-PLC_1_signaling_axis_drives_metastatic_progression_in_triple-negative_breast_cancer/3794620/1
Dataset