Projects per year
Personal profile
Education
- 2007 Ph.D. Graduate Institute of Pharmacognosy, Taipei Medical University
- 1999 M.S., School of Pharmacy, College of Medicine, Taipei Medical University
- 1993-1997 B.S., Department of Medical Laboratory Science and Biotechnology, Taipei Medical University
Experience
- 2021.02- Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2018.02-2021.01 Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2018.01-2014.07 Postdoctoral Researcher, Institute of Biological Chemistry, Academia Sinica
- 2014.09-2018.01 Assistant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
Awards
- 2015 Visiting Scholars, Genomics Research Center, Academia Sinica, Taiwan
- 2015 Reviewer for PLoS one
- 2008, 2009 and 2013 Reviewer for Journal of Cellular Biochemistry
Research Interests
- Cancer Drug Discovery
- Protein-Protein Interaction
Related Link
Fingerprint
Dive into the research topics where Yuan-Feng Lin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Studying on the Molecular Mechanism in Which Gbp5 Utilizes Inflammasome to Construct a Nf-Κb-Dependent Feedback Looping and Thereby Promotes Therapeutic Resistance, Metastasis and Immunosuppression in Oral Squamous Cell Carcinoma
Lin, Y.-F. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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利用Iodoacetamide衍生物找尋與鑑定新型藥物標靶用於治療多型性神經膠質母細胞瘤
Lin, Y.-F. (PI)
7/1/22 → 2/28/23
Project: A - Government Institution › b - National Science and Technology Council
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Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer
Lin, Y.-F. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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評估在三陰性乳癌中阻斷OTUD7B相關之訊息傳遞軸對於增強太平洋紫杉醇敏感度與抑制轉移能力的效果
Lin, Y.-F. (PI)
3/1/21 → 2/28/22
Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital
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利用人工智慧虛擬篩選平台鑑定DNA聚合?theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(2/3)
Lin, Y.-F. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma
Chiu, H. W., Lee, H. L., Lee, H. H., Lu, H. W., Lin, K. Y. H., Lin, Y. F. & Lin, C. H., Dec 2024, In: Journal of Translational Medicine. 22, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Guanylate binding protein 5 triggers NF-κB activation to foster radioresistance, metastatic progression and PD-L1 expression in oral squamous cell carcinoma
Chiu, H. W., Lin, C. H., Lee, H. H., Lu, H. W., Lin, Y. H. K., Lin, Y. F. & Lee, H. L., Feb 2024, In: Clinical Immunology. 259, 109892.Research output: Contribution to journal › Article › peer-review
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AIM2 upregulation promotes metastatic progression and PD-L1 expression in lung adenocarcinoma
Zheng, J. Q., Lin, C. H., Lee, H. H., Chang, W. M., Li, L. J., Su, C. Y., Lee, K. Y., Chiu, H. W. & Lin, Y. F., Jan 2023, In: Cancer Science. 114, 1, p. 306-320 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
NEDD8 promotes radioresistance via triggering autophagy formation and serves as a novel prognostic marker in oral squamous cell carcinoma
Yuan, T. Z., Lin, H. Y., Kuei, C. H., Lin, C. H., Lee, H. H., Lee, H. L., Lu, H. W., Su, C. Y., Chiu, H. W. & Lin, Y. F., Dec 2023, In: Cancer Cell International. 23, 1, 41.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Role of the Autism Risk Gene Shank3 in the Development of Atherosclerosis: Insights from Big Data and Mechanistic Analyses
Chang, H. W., Hsu, M. J., Chien, L. N., Chi, N. F., Yu, M. C., Chen, H. C., Lin, Y. F. & Hu, C. J., Nov 2023, In: Cells. 12, 21, 2546.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
Huang, S.-P. (Contributor), Liu, P.-Y. (Contributor), Kuo, C.-J. (Contributor), Chen, C.-L. (Contributor), Lee, W.-J. (Contributor), Tsai, Y.-H. (Creator) & Lin, Y.-F. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3794620.v1, https://figshare.com/collections/The_G_h-PLC_1_signaling_axis_drives_metastatic_progression_in_triple-negative_breast_cancer/3794620/1
Dataset
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Additional file 1: of Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Huang, M.-S. (Contributor), Jan, Y.-H. (Creator), Yang, C.-J. (Contributor), Hsiao, M. (Creator), Lin, Y.-F. (Creator) & Lai, T.-C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.7648181.v1, https://doi.org/10.6084%2Fm9.figshare.7648181.v1
Dataset
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Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Jan, Y.-H. (Creator), Lai, T.-C. (Contributor), Yang, C.-J. (Contributor), Lin, Y.-F. (Creator), Huang, M.-S. (Contributor) & Hsiao, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4383008.v1, https://doi.org/10.6084%2Fm9.figshare.c.4383008.v1
Dataset
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Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, Y.-C. (Creator), Chi, L.-H. (Contributor), Chang, W.-M. (Creator), Su, C.-Y. (Contributor), Lin, Y.-F. (Contributor), Chen, C.-L. (Creator), Chen, M.-H. (Creator), Chang, P.M.-H. (Creator), Wu, A. T. H. (Creator) & Hsiao, M. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368.v1, https://figshare.com/collections/Glucose_transporter_4_promotes_head_and_neck_squamous_cell_carcinoma_metastasis_through_the_TRIM24-DDX58_axis/3660368/1
Dataset
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Additional file 1: Table S1. of The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
Huang, S.-P. (Contributor), Liu, P.-Y. (Contributor), Kuo, C.-J. (Contributor), Chen, C.-L. (Contributor), Lee, W.-J. (Contributor), Tsai, Y.-H. (Contributor) & Lin, Y.-F. (Contributor), Unknown Publisher, Jun 2 2017
DOI: 10.6084/m9.figshare.c.3794620_d1.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_Table_S1_of_The_G_h-PLC_1_signaling_axis_drives_metastatic_progression_in_triple-negative_breast_cancer/5072119/1
Dataset