Projects per year
Personal profile
Education
- 2007 Ph.D. Graduate Institute of Pharmacognosy, Taipei Medical University
- 1999 M.S., School of Pharmacy, College of Medicine, Taipei Medical University
- 1993-1997 B.S., Department of Medical Laboratory Science and Biotechnology, Taipei Medical University
Experience
- 2021.02- Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2018.02-2021.01 Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2018.01-2014.07 Postdoctoral Researcher, Institute of Biological Chemistry, Academia Sinica
- 2014.09-2018.01 Assistant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
Awards
- 2015 Visiting Scholars, Genomics Research Center, Academia Sinica, Taiwan
- 2015 Reviewer for PLoS one
- 2008, 2009 and 2013 Reviewer for Journal of Cellular Biochemistry
Research Interests
- Cancer Drug Discovery
- Protein-Protein Interaction
Related Link
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Projects
- 15 Finished
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利用Iodoacetamide衍生物找尋與鑑定新型藥物標靶用於治療多型性神經膠質母細胞瘤
7/1/22 → 2/28/23
Project: A - Government Institution › b - Ministry of Science and Technology
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利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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評估在三陰性乳癌中阻斷OTUD7B相關之訊息傳遞軸對於增強太平洋紫杉醇敏感度與抑制轉移能力的效果
3/1/21 → 2/28/22
Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital
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利用人工智慧虛擬篩選平台鑑定DNA聚合?theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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探討SH2 Domain Containing 5 (SH2D5)促進大腸癌細胞進程之分子機轉
3/1/20 → 2/1/21
Project: C - Project of Alliance › n - Yuan's General Hospital
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AIM2 upregulation promotes metastatic progression and PD-L1 expression in lung adenocarcinoma
Zheng, J. Q., Lin, C. H., Lee, H. H., Chang, W. M., Li, L. J., Su, C. Y., Lee, K. Y., Chiu, H. W. & Lin, Y. F., Jan 2023, In: Cancer Science. 114, 1, p. 306-320 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
NEDD8 promotes radioresistance via triggering autophagy formation and serves as a novel prognostic marker in oral squamous cell carcinoma
Yuan, T. Z., Lin, H. Y., Kuei, C. H., Lin, C. H., Lee, H. H., Lee, H. L., Lu, H. W., Su, C. Y., Chiu, H. W. & Lin, Y. F., Dec 2023, In: Cancer Cell International. 23, 1, 41.Research output: Contribution to journal › Article › peer-review
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Histone deacetylase inhibition improves metabolism and mitochondrial dynamics: A potential novel therapeutic strategy for sarcopenia coexisting with diabetes mellitus
Lee, T. W., Liu, H. W., Lin, Y. F., Lee, T. I., Kao, Y. H. & Chen, Y. J., Jan 2022, In: Medical Hypotheses. 158, 110724.Research output: Contribution to journal › Article › peer-review
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BICD cargo adaptor 1 (BICD1) downregulation correlates with a decreased level of PD-L1 and predicts a favorable prognosis in patients with IDH1-mutant lower-grade gliomas
Huang, S. P., Li, C. H., Chang, W. M. & Lin, Y. F., Aug 2021, In: Biology. 10, 8, 701.Research output: Contribution to journal › Article › peer-review
Open Access -
Gbp5 repression suppresses the metastatic potential and pd-l1 expression in triple-negative breast cancer
Cheng, S. W., Chen, P. C., Lin, M. H., Ger, T. R., Chiu, H. W. & Lin, Y. F., Apr 2021, In: Biomedicines. 9, 4, 371.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus)
Datasets
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Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Jan, Y. (Creator), Lai, T. (Contributor), Yang, C. (Contributor), Lin, Y. (Creator), Huang, M. (Contributor) & Hsiao, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4383008.v1, https://doi.org/10.6084%2Fm9.figshare.c.4383008.v1
Dataset
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The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
Huang, S. (Contributor), Liu, P. (Contributor), Kuo, C. (Contributor), Chen, C. (Contributor), Lee, W. (Contributor), Tsai, Y. (Creator) & Lin, Y. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3794620.v1, https://figshare.com/collections/The_G_h-PLC_1_signaling_axis_drives_metastatic_progression_in_triple-negative_breast_cancer/3794620/1
Dataset
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Additional file 1: Table S1. of Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, W. (Creator), Hsiao, M. (Creator), Su, C. (Contributor), Chang, P. M. (Creator), Lin, Y. (Contributor), Wu, A. T. (Creator), Chen, C. (Creator), Chi, L. (Contributor), Chen, M. (Creator) & Chang, Y. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3660368_d1.v1
Dataset
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Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Chang, Y. (Creator), Chi, L. (Contributor), Chang, W. (Creator), Su, C. (Contributor), Lin, Y. (Contributor), Chen, C. (Creator), Chen, M. (Creator), Chang, P. M. (Creator), Wu, A. T. (Creator) & Hsiao, M. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3660368.v1, https://figshare.com/collections/Glucose_transporter_4_promotes_head_and_neck_squamous_cell_carcinoma_metastasis_through_the_TRIM24-DDX58_axis/3660368/1
Dataset
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Additional file 1: of Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
Huang, M. (Contributor), Jan, Y. (Creator), Yang, C. (Contributor), Hsiao, M. (Creator), Lin, Y. (Creator) & Lai, T. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.7648181.v1, https://doi.org/10.6084%2Fm9.figshare.7648181.v1
Dataset