Personal profile
Education
- 2008 Ph.D Rutgers UniversityPharmacology
- 1998 M.S., Institute of Biochemistry and Molecular Biology
- 1996 B.S., Department of Agriculture Chemistry, National Taiwan University
Experience
- 2018- Assiociate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018- Assiociate Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2013-2018 Assistant Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2009-2013 Postdoc, Princeton University
Research Interests
- tumor microenvironment
- tumor biology
- DNA damage
- vaccine design
Related Link
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Collaborations and top research areas from the last five years
Projects
- 10 Finished
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Study Molecular Mechanisms That Underlie the Anti-Tumor Effects against Pancreatic Cancer via Inhibition of Interleukin-1 Receptor Antagonist (Il-1ra)
Tsai, Y.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Study Roles of Interleukin-1 Receptor Antagonist (Il1rn) in Pancreatic Cancer
Tsai, Y.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Study Roles of Interleukin-1 Receptor Antagonist (Il1rn) in Pancreatic Cancer (2/3)
Tsai, Y.-C. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Study Roles of Interleukin-1 Receptor Antagonist (Il1rn) in Pancreatic Cancer
Tsai, Y.-C. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Studies of Prostate Cancer Progression after Androgen-Deprivation Therapy and Development of Cancer Immunotherapy via Anti-Inflammation Approaches
Tsai, Y.-C. (PI)
8/1/18 → 7/1/19
Project: A - Government Institution › b - National Science and Technology Council
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Disruption of CCL2 in Mesenchymal Stem Cells as an Anti-Tumor Approach against Prostate Cancer
Bui, Q. T., Lee, K. D., Fan, Y. C., Lewis, B. S., Deng, L. W. & Tsai, Y. C., Jan 2023, In: Cancers. 15, 2, 441.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Citations (Scopus) -
Tumor-derived interleukin-1 receptor antagonist exhibits immunosuppressive functions and promotes pancreatic cancer
Fan, Y. C., Fong, Y. C., Kuo, C. T., Li, C. W., Chen, W. Y., Lin, J. D., Bürtin, F., Linnebacher, M., Bui, Q. T., Lee, K. D. & Tsai, Y. C., Dec 2023, In: Cell and Bioscience. 13, 1, 147.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Citations (Scopus) -
Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes
Tsai, Y. C., Huang, C. Y., Hsueh, Y. M., Fan, Y. C., Fong, Y. C., Huang, S. P., Geng, J. H., Chen, L. C., Lu, T. L. & Bao, B. Y., Jun 15 2021, In: Life Sciences. 275, 119396.Research output: Contribution to journal › Article › peer-review
11 Link opens in a new tab Citations (Scopus) -
Investigation of anti-tumor effects of an MLK1 inhibitor in prostate and pancreatic cancers
Fan, Y. C., Hsu, K. C., Lin, T. E., Zechner, D., Hsu, S. P. & Tsai, Y. C., Aug 2021, In: Biology. 10, 8, 742.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
Roles of interleukin-1 receptor antagonist in prostate cancer progression
Fan, Y. C., Lee, K. D. & Tsai, Y. C., Dec 2020, In: Biomedicines. 8, 12, p. 1-13 13 p., 602.Research output: Contribution to journal › Article › peer-review
Open Access13 Link opens in a new tab Citations (Scopus)
Datasets
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Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
Tsai, Y.-C. (Contributor), Zeng, T. (Creator), Abou-Kheir, W. (Creator), Yeh, H.-L. (Contributor), Yin, J. J. (Creator), Lee, Y.-C. (Creator), Chen, W.-Y. (Creator) & Liu, Y.-N. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4008787.v1, https://doi.org/10.6084%2Fm9.figshare.c.4008787.v1
Dataset
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Additional file 1: of Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
Tsai, Y.-C. (Contributor), Zeng, T. (Creator), Abou-Kheir, W. (Creator), Yeh, H.-L. (Contributor), Yin, J. J. (Creator), Lee, Y.-C. (Creator), Chen, W.-Y. (Creator) & Liu, Y.-N. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.5900626.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Disruption_of_ETV6_leads_to_TWIST1-dependent_progression_and_resistance_to_epidermal_growth_factor_receptor_tyrosine_kinase_inhibitors_in_prostate_cancer/5900626/1
Dataset