Projects per year
Personal profile
Education
- 1999 Ph.D. Toxicology, National Taiwan University
- 1995 M.S. Toxicology, National Taiwan University
- 1990 B.S. Department of Food Science and Nutrition, Shih Chien University
Experience
- 2016-2017 Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2013- Ph.D. Program in Clinical Drug Development of Herbal Medicine, Taipei Medical University
- 2013- Professor, Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, Taipei Medical University
- 2013- Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2012-2013 Associate Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2005-2012 Associate Professor, School of Pharmacy, Taipei Medical University
- 2000-2005 Assistant Professor, School of Pharmacy, Taipei Medical University
Research Interests
- Drugs Development of Antimucositis and Anticancer.
- Drugs Development of Retinopathy and Age-Relative Macular Degeneration Diseases.
- Toxicity testing for food, drugs and cosmetics.
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Potential Therapeutic Effects of Aza-Pbha on Diabetes Induced Retinopathy through Ahr-Mediated Pathway
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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The Potential Therapeutic Mechanisms of Aryl Aromatic Hydrocarbon Receptor in Blue Light-Induced Retinopathy( III )
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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組織蛋白去乙醯酶異構酵素應用於藍光誘發之乾性黃斑部病變與其治療機制探討
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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The Potential Therapeutic Mechanisms of Aryl Aromatic Hydrocarbon Receptor in Blue Light-Induced Retinopathy( II )
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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Aza-PBHA , 透過調控芳香烴受體於糖尿病視網膜病變治療潛力機制探討(2/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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Retinal protection by fungal product theissenolactone B in a sodium iodate-induced AMD model through targeting retinal pigment epithelial matrix metalloproteinase-9 and microglia activity
Lin, F. L., Cheng, Y. W., Chen, L. H., Ho, J. D., Yen, J. L., Wang, M. H., Lee, T. H. & Hsiao, G., Feb 2023, In: Biomedicine and Pharmacotherapy. 158, 114138.Research output: Contribution to journal › Article › peer-review
Open Access -
The HDAC/HSP90 inhibitor G570 attenuated blue light-induced cell migration in RPE cells and neovascularization in mice through decreased VEGF production
Hsu, T. J., Nepali, K., Tsai, C. H., Imtiyaz, Z., Lin, F. L., Hsiao, G., Lai, M. J. & Cheng, Y. W., Jul 2 2021, In: Molecules. 26, 14, 4359.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Chan, Y. J., Liao, P. L., Tsai, C. H., Cheng, Y. W., Lin, F. L., Ho, J. D., Chen, C. Y. & Li, C. H., Jan 9 2021, In: Particle and Fibre Toxicology. 18, 1, p. 4 4.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Aryl hydrocarbon receptor deficiency enhanced airway inflammation and remodeling in a murine chronic asthma model
Chang, Y. D., Li, C. H., Tsai, C. H., Cheng, Y. W., Kang, J. J. & Lee, C. C., Nov 1 2020, In: FASEB Journal. 34, 11, p. 15300-15313 14 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions
Tsai, C. H., Li, C. H., Liao, P. L., Chang, Y. W., Cheng, Y. W. & Kang, J. J., Feb 2020, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1867, 2, 118564.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)
Datasets
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Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Chan, Y. (Contributor), Cheng, Y. (Creator), Liao, P. (Contributor), Li, C. (Creator), Lin, F. (Contributor), Ho, J. (Contributor), Chen, C. (Contributor) & Tsai, C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5263303.v1, https://doi.org/10.6084%2Fm9.figshare.c.5263303.v1
Dataset
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Additional file 1 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Ho, J. (Contributor), Lin, F. (Contributor), Tsai, C. (Contributor), Liao, P. (Contributor), Chan, Y. (Contributor), Cheng, Y. (Creator), Li, C. (Creator) & Chen, C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.13550758.v1, https://doi.org/10.6084%2Fm9.figshare.13550758.v1
Dataset
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MOESM1 of Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
Chen, C. (Contributor), Liao, P. (Contributor), Tsai, C. (Contributor), Chan, Y. (Contributor), Cheng, Y. (Contributor), Hwang, L. (Contributor), Lin, K. (Contributor), Yen, T. (Contributor) & Li, C. (Contributor), Unknown Publisher, Oct 16 2019
DOI: 10.6084/m9.figshare.9994028.v1, https://springernature.figshare.com/articles/MOESM1_of_Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/9994028/1
Dataset
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Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
Chen, C. (Contributor), Liao, P. (Contributor), Tsai, C. (Contributor), Chan, Y. (Contributor), Cheng, Y. (Creator), Hwang, L. (Creator), Lin, K. (Contributor), Yen, T. (Contributor) & Li, C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4701761.v1, https://springernature.figshare.com/collections/Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/4701761/1
Dataset
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Additional file 2 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Li, C. (Creator), Ho, J. (Contributor), Chan, Y. (Contributor), Chen, C. (Contributor), Cheng, Y. (Creator), Lin, F. (Contributor), Liao, P. (Contributor) & Tsai, C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.13550761.v1, https://doi.org/10.6084%2Fm9.figshare.13550761.v1
Dataset