Projects per year
Personal profile
Education
- 1999 Ph.D. Toxicology, National Taiwan University
- 1995 M.S. Toxicology, National Taiwan University
- 1990 B.S. Department of Food Science and Nutrition, Shih Chien University
Experience
- 2016-2017 Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2013- Ph.D. Program in Clinical Drug Development of Herbal Medicine, Taipei Medical University
- 2013- Professor, Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, Taipei Medical University
- 2013- Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2012-2013 Associate Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2005-2012 Associate Professor, School of Pharmacy, Taipei Medical University
- 2000-2005 Assistant Professor, School of Pharmacy, Taipei Medical University
Research Interests
- Drugs Development of Antimucositis and Anticancer.
- Drugs Development of Retinopathy and Age-Relative Macular Degeneration Diseases.
- Toxicity testing for food, drugs and cosmetics.
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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視覺循環抑制劑藉由調控褐紫質堆積對抗藍光誘發之乾性黃斑部病變於離體色素上皮細胞與活體小鼠視網膜之功效探討(1/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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112年度【產學合作計畫-藥用真菌猴頭菇與蟬花應用於神經損傷性視網膜病變功效開發】
6/1/23 → 5/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Potential Therapeutic Effects of Aza-Pbha on Diabetes Induced Retinopathy through Ahr-Mediated Pathway
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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The Potential Therapeutic Mechanisms of Aryl Aromatic Hydrocarbon Receptor in Blue Light-Induced Retinopathy( III )
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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組織蛋白去乙醯酶異構酵素應用於藍光誘發之乾性黃斑部病變與其治療機制探討
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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Activation of aryl hydrocarbon receptor by azatyrosine-phenylbutyric hydroxamide inhibits progression of diabetic retinopathy mice
Fitriana, I., Wu, C. H., Hsu, T. J., Chan, Y. J., Li, C. H., Lee, C. C., Hsiao, G. & Cheng, Y. W., Sept 2023, In: Biochemical Pharmacology. 215, 115700.Research output: Contribution to journal › Article › peer-review
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Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17
Chan, Y. J., Hsiao, G., Wan, W. N., Yang, T. M., Tsai, C. H., Kang, J. J., Lee, Y. C., Fang, T. C., Cheng, Y. W. & Li, C. H., Dec 2023, In: Fluids and Barriers of the CNS. 20, 1, 31.Research output: Contribution to journal › Article › peer-review
Open Access -
Machine learning approaches for predicting 5-year breast cancer survival: A multicenter study
Nguyen, Q. T. N., Nguyen, P. A., Wang, C. J., Phuc, P. T., Lin, R. K., Hung, C. S., Kuo, N. H., Cheng, Y. W., Lin, S. J., Hsieh, Z. Y., Cheng, C. T., Hsu, M. H. & Hsu, J. C., 2023, (Accepted/In press) In: Cancer Science.Research output: Contribution to journal › Article › peer-review
Open Access -
Retinal protection by fungal product theissenolactone B in a sodium iodate-induced AMD model through targeting retinal pigment epithelial matrix metalloproteinase-9 and microglia activity
Lin, F. L., Cheng, Y. W., Chen, L. H., Ho, J. D., Yen, J. L., Wang, M. H., Lee, T. H. & Hsiao, G., Feb 2023, In: Biomedicine and Pharmacotherapy. 158, 114138.Research output: Contribution to journal › Article › peer-review
Open Access -
The HDAC/HSP90 inhibitor G570 attenuated blue light-induced cell migration in RPE cells and neovascularization in mice through decreased VEGF production
Hsu, T. J., Nepali, K., Tsai, C. H., Imtiyaz, Z., Lin, F. L., Hsiao, G., Lai, M. J. & Cheng, Y. W., Jul 2 2021, In: Molecules. 26, 14, 4359.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)
Datasets
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Additional file 2 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Li, C. (Creator), Ho, J. (Contributor), Chan, Y. (Contributor), Chen, C. (Contributor), Cheng, Y. (Creator), Lin, F. (Contributor), Liao, P. (Contributor) & Tsai, C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.13550761.v1, https://doi.org/10.6084%2Fm9.figshare.13550761.v1
Dataset
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Additional file 1 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Ho, J. (Contributor), Lin, F. (Contributor), Tsai, C. (Contributor), Liao, P. (Contributor), Chan, Y. (Contributor), Cheng, Y. (Creator), Li, C. (Creator) & Chen, C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.13550758.v1, https://doi.org/10.6084%2Fm9.figshare.13550758.v1
Dataset
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MOESM1 of Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
Chen, C. (Contributor), Liao, P. (Contributor), Tsai, C. (Contributor), Chan, Y. (Contributor), Cheng, Y. (Contributor), Hwang, L. (Contributor), Lin, K. (Contributor), Yen, T. (Contributor) & Li, C. (Contributor), Unknown Publisher, Oct 16 2019
DOI: 10.6084/m9.figshare.9994028.v1, https://springernature.figshare.com/articles/MOESM1_of_Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/9994028/1
Dataset
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Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Chan, Y. (Contributor), Cheng, Y. (Creator), Liao, P. (Contributor), Li, C. (Creator), Lin, F. (Contributor), Ho, J. (Contributor), Chen, C. (Contributor) & Tsai, C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5263303.v1, https://doi.org/10.6084%2Fm9.figshare.c.5263303.v1
Dataset
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Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
Chen, C. (Contributor), Liao, P. (Contributor), Tsai, C. (Contributor), Chan, Y. (Contributor), Cheng, Y. (Creator), Hwang, L. (Creator), Lin, K. (Contributor), Yen, T. (Contributor) & Li, C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4701761.v1, https://springernature.figshare.com/collections/Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/4701761/1
Dataset