Projects per year
Personal profile
Education
- 2012 Ph.D. Neuroscience, National Defense Medical Center, Taiwan
- 2006 Master of Science Neurobiology and Behavior, National Defense Medical Center, Taiwan
- 2004 Bachelor of Science Life Science, National Chiayi University
Experience
Teaching Experience
- 2023.11- Assistant Professor, International Master Program for Translational Science, Taipei Medical University
- 2023.11- Joint-Appointment Assistant Professor, International Ph.D. Program for Translational Science, Taipei Medical University
- 2023 Joint-Appointment Assistant Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University
- 2011-2012 Adjunct Lecturer, Department of Science Education and Application, National Taichung University of Education, Taiwan
Research Experience
- 2014.01-2022.04 Department of Pharmacology, University of Minnesota – Minneapolis, MN
- Project 1: Investigated the regulatory mechanism and therapeutic effects of CRABP1 in an Amyotrophic lateral sclerosis disease model
- Established a novel 3D co-culture model using motor neurons and skeletal myotubes.
- Established a whole mounting IF staining for neuromuscular junction.
- Project 2: Investigated the non-canonical signaling mechanism of CRABP1 in stem cells.
- Established a novel and non-canonical retinoic acid signaling pathway in the cytoplasm of embryonic stem cells.
- Collaborated with colleagues to uncover the role of CRABP1 in cancer therapy.
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Project 3: Investigated the role of RIP140 in neuron stress and murine behavior.
- Performed mouse brain stereotaxic surgery with lentivirus infection to knockdown RIP140 expression.
- Collaborated with colleagues to uncover the role of RIP140 in mouse anxiety.
- Other:
- Mentored junior scientists and students to conduct experiments for various projects.
- Managed laboratory in various aspects including ordering, animal facility, chemicals, and controlled substance.
- Project 1: Investigated the regulatory mechanism and therapeutic effects of CRABP1 in an Amyotrophic lateral sclerosis disease model
- 2012.07-2012.11 Postdoctoral Associate, Institute Of Biomedical Engineering & Nanomedicine, National Health Research Institutes, Taiwan
Research Interests
- Neuroscience
- Motor neuron diseases
- Stem cell
- Cell culture
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Collaborations and top research areas from the last five years
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Projects
- 2 Finished
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探討運動神經元SARM1在漸凍人症的神經軸突退化過程中對許旺細胞與肌肉的影響與機轉(1/2)
Lin, Y.-L. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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新聘教師研究補助
Lin, Y.-L. (PI)
5/1/23 → 4/30/24
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
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RRM2 inhibition alters cell cycle through ATM/Rb/E2F1 pathway in atypical teratoid rhabdoid tumor
Giang, L. H., Wu, K. S., Lee, W. C., Chu, S. S., Do, A. D., Huang, M. H., Lin, Y. L., Hsieh, C. L., Sung, S. Y., Yen, Y., Wong, T. T. & Chang, C. C., Dec 2024, In: Neoplasia (United States). 58, 101075.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel 3D bilayer hydrogel tri-culture system for studying functional motor units
Lin, Y. L., Nhieu, J., Lerdall, T., Milbauer, L., Wei, C. W., Lee, D. J., Oh, S. H., Thayer, S. & Wei, L. N., Dec 2023, In: Cell and Bioscience. 13, 1, 168.Research output: Contribution to journal › Article › peer-review
Open Access -
RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury
Liu, P. Y., Chen, C. Y., Lin, Y. L., Lin, C. M., Tsai, W. C., Tsai, Y. L., Lin, G. J., Chen, Y. G., Wang, S. Y., Sun, R. N., Huang, Y. C., Chang, H. & Chen, Y. C., Jun 2023, In: Cell Death and Disease. 14, 6, 369.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
CRABP1-CaMKII-Agrn regulates the maintenance of neuromuscular junction in spinal motor neuron
Lin, Y. L., Nhieu, J., Liu, P. Y., Le, G., Lee, D. J., Wei, C. W., Lin, Y. W., Oh, S. H., Lowe, D. & Wei, L. N., Sept 2022, In: Cell Death and Differentiation. 29, 9, p. 1744-1756 13 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
CRABP1 in Non-Canonical Activities of Retinoic Acid in Health and Diseases
Nhieu, J., Lin, Y. L. & Wei, L. N., Apr 2022, In: Nutrients. 14, 7, 1528.Research output: Contribution to journal › Review article › peer-review
Open Access15 Citations (Scopus)