Projects per year
Personal profile
Education
- 2008 Ph.D. Medical Sciences, Tzu Chi University
- 2003 M.S. Human Genetics, Tzu Chi University
Experience
- 2024.08- Director, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2022-2023 Visiting Research Scholar, Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School
- 2019- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019- Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018-2019 Associate Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2017-2018 Visiting Research Scholar, Department of Pathology, Duke University Medical Center
- 2016-2019 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2012-2016 Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2009 Postdoctoral Researcher, National Institutes of Health (NIH), USA
Awards
- 2018 Ta-You Wu Memorial Award, National Science and Technology Council, Taiwan
- 2018 Young Researcher Cancer Research Excellence Award, Taiwan Oncology Society, Taiwan
- 2015 Young Scholar Award, Taipei Medical University, Taiwan
- 2014 Excellent Research Award, Taipei Medical University, Taiwan
- 2014 Young Scholar Award, Taipei Medical University, Taiwan
Research Interests
- Molecular and Cellular Biology
- Tumor Metastasis and Signal Transduction
- Cancer Metabolism
- Cancer immunotherapy
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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研究IL1RN 和CCL7在M2-like 巨噬細胞分化中的調控作用及對前列腺癌腫瘤微環境中CCL20 驅動的神經內分泌分化的分子機制
Liu, Y.-N. (PI)
1/1/25 → 12/31/25
Project: B - Project of TMU › i - Other (Funded by TMU)
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整合代謝基因調控機轉與合成基因電路載體在神經內分泌前列腺癌免疫治療的應用
Liu, Y.-N. (PI)
1/1/25 → 12/31/25
Project: A - Government Institution › a - National Health Research Institutes
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Establishing Anti-Inflammatory Metabolomic Database of Tcms Using Chemical Molecular Networking Approach
Liu, Y.-N. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Next-Generation Tumor Immunotherapy for Neuroendocrine Prostate Cancer
Liu, Y.-N. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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探討腦源性神經營養因子在治療誘導的 神經內分泌前列腺癌的免疫抑制功能
Liu, Y.-N. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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Binding of interleukin-1 receptor antagonist to cholinergic receptor muscarinic 4 promotes immunosuppression and neuroendocrine differentiation in prostate cancer
Liu, Y. N., Liu, M. K., Wen, Y. C., Li, C. H., Yeh, H. L., Dung, P. V. T., Jiang, K. C., Chen, W. H., Li, H. R., Huang, J. & Chen, W. Y., Aug 28 2024, In: Cancer Letters. 598, 217090.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Correction: CHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer (Cell Death & Disease, (2023), 14, 5, (304), 10.1038/s41419-023-05836-7)
Wen, Y. C., Tram, V. T. N., Chen, W. H., Li, C. H., Yeh, H. L., Thuy Dung, P. V., Jiang, K. C., Li, H. R., Huang, J., Hsiao, M., Chen, W. Y. & Liu, Y. N., Jan 2024, In: Cell Death and Disease. 15, 1, 92.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Citation (Scopus) -
Immunosuppressive role of BDNF in therapy-induced neuroendocrine prostate cancer
Liu, Y. N., Chen, W. Y., Liu, M. K., Yeh, H. L., Chen, W. H., Jiang, K. C., Li, H. R., Chen, Z. Q., Wang, W. H., Abou-Kheir, W. & Wen, Y. C., 2024, (Accepted/In press) In: Molecular Oncology. 18, 6, p. 1665-1686 22 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
MCTP1 increases the malignancy of androgen-deprived prostate cancer cells by inducing neuroendocrine differentiation and EMT
Liu, Y. N., Chen, W. Y., Yeh, H. L., Chen, W. H., Jiang, K. C., Li, H. R., Thuy Dung, P. V., Chen, Z. Q., Lee, W. J., Hsiao, M., Huang, J. & Wen, Y. C., 2024, In: Science Signaling. 17, 840, adc9142.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
WNT1-inducible signaling pathway protein 1 activation through C-X-C motif chemokine ligand 5/C-X-C chemokine receptor type 2/leukemia inhibitory factor/leukemia inhibitory factor receptor signaling promotes immunosuppression and neuroendocrine differentiation in prostate cancer
Tsui, K. H., Liu, C. L., Yeh, H. L., Liu, M. K., Li, C. H., Chen, W. H., Jiang, K. C., Li, H. R., Thuy Dung, P. V., Hsiao, M., Abou-Kheir, W. & Liu, Y. N., Aug 16 2024, In: iScience. 27, 8, 110562.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
Tsai, Y.-C. (Contributor), Zeng, T. (Creator), Abou-Kheir, W. (Creator), Yeh, H.-L. (Contributor), Yin, J. J. (Creator), Lee, Y.-C. (Creator), Chen, W.-Y. (Creator) & Liu, Y.-N. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4008787.v1, https://doi.org/10.6084%2Fm9.figshare.c.4008787.v1
Dataset
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Additional file 1: of Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
Tsai, Y.-C. (Contributor), Zeng, T. (Creator), Abou-Kheir, W. (Creator), Yeh, H.-L. (Contributor), Yin, J. J. (Creator), Lee, Y.-C. (Creator), Chen, W.-Y. (Creator) & Liu, Y.-N. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.5900626.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Disruption_of_ETV6_leads_to_TWIST1-dependent_progression_and_resistance_to_epidermal_growth_factor_receptor_tyrosine_kinase_inhibitors_in_prostate_cancer/5900626/1
Dataset