Projects per year
Personal profile
Education
- 2008 Ph.D. Medical Sciences, Tzu Chi University
- 2003 M.S. Human Genetics, Tzu Chi University
Experience
- 2022-2023 Visiting Research Scholar, Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School
- 2019- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019- Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2018-2019 Associate Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2017-2018 Visiting Research Scholar, Department of Pathology, Duke University Medical Center
- 2016-2019 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2012-2016 Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2009 Post-doctoral Fellow, National Institutes of Health
Awards
- 2022 National Science and Technology Council 2030 Cross-Generation Young Scholars Program Excellent Young Scholars, Taiwan
- 2021 Research Award(Granted Three Times), National Health Research Institutes(NHRI), Taiwan
- 2018 Ta-You Wu Memorial Award, Ministry of Science and Technology, Taiwan
- 2018 Excellent Young Scholars, National Science and Technology Council,Taiwan
- 2018 Young Researcher Cancer Research Excellence Award, Taiwan Oncology Society, Taiwan
- 2016 Excellent Young Scholars, National Science and Technology Council,Taiwan
- 2015 Young Scholar Award, Taipei Medical University, Taiwan
- 2014 Excellent Research Award, Taipei Medical University, Taiwan
- 2014 Young Scholar Award, Taipei Medical University, Taiwan
- 2014-2017 Career Development Grant (CDG), National Health Research Institutes(NHRI), Taiwan
- 2003 Master Degree Thesis Award, National Science Council, Taiwan
Research Interests
- Molecular Cellular Biology
- Cancer metastasis
- Gene Regulation
- Signal Transduction
Fingerprint
- 1 Similar Profiles
Network
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(精準醫療)研究LIF/LIFR驅動前列腺癌免疫抑制腫瘤微環境的分子機制
3/1/23 → 2/29/24
Project: C - Project of Alliance › o - Chi Mei Medical Center
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ZBTB46-PCK1訊息傳遞調控前列腺癌進展的分子機轉及治療意義
1/1/23 → 12/31/23
Project: A - Government Institution › a - National Health Research Institutes
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ZBTB46-PCK1訊息傳遞調控前列腺癌進展的分子機轉及治療意義(優秀資深研究助理獎助)
1/1/23 → 12/31/23
Project: A - Government Institution › a - National Health Research Institutes
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Study the Molecular Mechanism of Chrm4 Driving the Anti-Inflammatory Response in the Tumor Microenvironment of Prostate Cancer and the Development of Novel Combination Immunotherapy( I )
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Identification Pklr Metabolic Pathways and Therapeutic Roles in Promoting Neuroendocrine Differentiation of Prostate Cancer
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Targeting PKLR/MYCN/ROMO1 signaling suppresses neuroendocrine differentiation of castration-resistant prostate cancer
Chen, W. Y., Thuy Dung, P. V., Yeh, H. L., Chen, W. H., Jiang, K. C., Li, H. R., Chen, Z. Q., Hsiao, M., Huang, J., Wen, Y. C. & Liu, Y. N., Jun 2023, In: Redox Biology. 62, 102686.Research output: Contribution to journal › Article › peer-review
Open Access -
PCK1 regulates neuroendocrine differentiation in a positive feedback loop of LIF/ZBTB46 signalling in castration-resistant prostate cancer
Wen, Y. C., Liu, C. L., Yeh, H. L., Chen, W. H., Jiang, K. C., Tram, V. T. N., Hsiao, M., Huang, J., Chen, W. Y. & Liu, Y. N., Mar 23 2022, In: British Journal of Cancer. 126, 5, p. 778-790 13 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency
Wen, Y. C., Chen, W. Y., Tram, V. T. N., Yeh, H. L., Chen, W. H., Jiang, K. C., Abou-Kheir, W., Huang, J., Hsiao, M. & Liu, Y. N., Mar 2022, In: Cell Death and Disease. 13, 3, 252.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Interplay of epidermal growth factor receptor and signal transducer and activator of transcription 3 in prostate cancer: Beyond androgen receptor transactivation
Lin, S. R., Yeh, H. L. & Liu, Y. N., Jul 2 2021, In: Cancers. 13, 14, 3452.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance
Chen, W. Y., Wen, Y. C., Lin, S. R., Yeh, H. L., Jiang, K. C., Chen, W. H., Lin, Y. S., Zhang, Q., Liew, P. L., Hsiao, M., Huang, J. & Liu, Y. N., Dec 2021, In: Communications Biology. 4, 1, 22.Research output: Contribution to journal › Article › peer-review
Open Access21 Citations (Scopus)
Datasets
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Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
Tsai, Y. (Contributor), Zeng, T. (Creator), Abou-Kheir, W. (Creator), Yeh, H. (Contributor), Yin, J. J. (Creator), Lee, Y. (Creator), Chen, W. (Creator) & Liu, Y. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4008787.v1, https://doi.org/10.6084%2Fm9.figshare.c.4008787.v1
Dataset
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Additional file 1: of Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
Tsai, Y. (Contributor), Zeng, T. (Creator), Abou-Kheir, W. (Creator), Yeh, H. (Contributor), Yin, J. J. (Creator), Lee, Y. (Creator), Chen, W. (Creator) & Liu, Y. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.5900626.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Disruption_of_ETV6_leads_to_TWIST1-dependent_progression_and_resistance_to_epidermal_growth_factor_receptor_tyrosine_kinase_inhibitors_in_prostate_cancer/5900626/1
Dataset