Projects per year
Personal profile
Education
- 2009-2015 Ph.D., Institute of Biochemistry and Molecular Biology, National Yang Ming University
- 2007-2009 M.S., Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University
- 2000-2004 B.S., Department of Life Science, Tzu Chi University
Experience
- 2024.02- Associate Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
- 2024.02- Joint-Appointment Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2020.02-2024.01 Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2019.06-2024.01 Assistant Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
- 2016.08-2019.06 Postdoctoral Research Fellow, Johns Hopkins University
- 2015.08-2016.08 Postdoctoral Research Fellow, National Yang-Ming University
- 2015.02-2015.07 Postdoctoral Research Fellow, Taipei Veterans General Hospital
Research Interests
- Translational Medicine, Cancer Stem Cell, Metabolism, Nanomedicine
Awards
- 2018.03.14 Pathology Award – 20th Annual Department of Pathology Young Investigators' Day, Johns Hopkins University, USA
- 2016.11.28 Postdoctoral Research Abroad Program (PRAP) Award – Ministry of Science and Technology, Taiwan
- 2013.11.06 Young Investigator Award – International Symsposium on Mitochondria 2013 / The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit), Japan
- 2013.11.04 Young Investigator Award – 10th Conference of the Asian Society of Mitochondrial Research and Medicine (ASMRM), Korea
- 2013.10.19 First prize of Poster Award – 2013 Mini-symposium on Mitochondria and Aging, Taiwan
- 2013.10.16 Young Investigator Award – 6th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), Taiwan
- 2013.09.07 Third Prize of Poster Award – 2013 International Symposium on Mitochondrial Dynamics in Translational Medicine, Taiwan
- 2012.11.02 Young Investigator Award – 2012 Conference of 9th ASMRM Beijing, China
- 2012.10.26 Silver Medal Award of Oral Session Competition – 7th International Symposium on Genomic Medicine of CCH, Taiwan
- 2011.10.07 Fellowships Award – 22nd FAOBMB Conference, Singapore
- 2011.08.31 Young Investigator Award – 2011 8th Conference of ASMRM in Kagoshima, Japan
- 2011.07.09 First prize of Poster Award – 2011 Mackay International Symposium on Mitochondrial Medicine in Human Health and Diseases in Taipei, Taiwan
- 2010.12.15 Young Investigator Award – 2010 7th Conference of ASMRM in Fukuoka, Japan
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 6 Similar Profiles
Collaborations and top research areas from the last five years
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以糖化奈米藥物扭轉代謝代償及協同抑制轉錄活性作為胰臟癌幹細胞新穎治療策略(3/4)
Shen, Y.-A. (PI)
8/1/26 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
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Repurposing S1R Antagonists to Target the S1R-MAM Axis and Overcome Therapeutic Resistance in Liver Cancer Stem Cells
Shen, Y.-A. (PI)
7/1/26 → 2/28/27
Project: A - Government Institution › b - National Science and Technology Council
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Tumor Acidity–Triggered BA-MSN Delivery of PBX1 Inhibitors to Reprogram Stemness and Sensitize Pancreatic Cancer Subpopulations to Gemcitabine
Shen, Y.-A. (PI)
7/1/26 → 2/28/27
Project: A - Government Institution › b - National Science and Technology Council
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運用中孔洞二氧化矽奈米載體傳遞PBX1抑制劑克服吉西他濱所誘導抗藥性胰臟癌之癌幹細胞特性
Shen, Y.-A. (PI)
1/1/26 → 12/31/26
Project: A - Government Institution › a - National Health Research Institutes
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Utilizing Glucosamine-Labeled Nanodrugs as a Novel Pancreatic Cancer Stem Cell Therapy to Counteract Metabolic Compensation and Synergistically Inhibit Transcriptional Activity( II )
Shen, Y.-A. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Critical radiosensitizing parameters of dual-modality gold nanodandelion against cancer radioresistance in MV X-ray and proton therapies
Chuang, Y. C., Chiou, J. F., Wu, P. H., Shen, Y. A., Chang, W. M., Hsia, Y., Kuo, C. C., Wang, W. J., Lo, L. W. & Lee, H. L., Jun 2026, In: Materials Today Advances. 30, 100757.Research output: Contribution to journal › Article › peer-review
Open Access -
Fibronectin 1 mediates pressure-induced aggressive phenotypes in colorectal cancer cells and cancer stem cells
Nguyen, V. C., Cheng, K. C., Phan, T. T. T., Ho, T. L., Lin, Y. H., Kuo, L. J., Shen, Y. A. & Chen, C. L., Dec 2026, In: Cancer Cell International. 26, 1, 289.Research output: Contribution to journal › Article › peer-review
Open Access -
Sclerofish A and B: Two Pairs of Enantiomeric Diterpenoids Featuring a 4/7/6-Fused Tricyclic Scaffold from the Soft Coral Sclerophytum humesi
Luu, P. V., Phan, T. T. T., Huynh, Q. D. T., Pham, N. T., Le, H. G., Chen, L. Y., Ton-Nu, H. L., Nguyen, C. Q., Shen, Y. A., Fan, Y. J., Su, J. H., Peng, B. R. & Lai, K. H., Jun 19 2026, In: Journal of Organic Chemistry. 91, 24, p. 8230-8240 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Sclerohumins G-L: Selective cytotoxic diterpenoids featuring a 4/9-fused ring system from the soft coral Sclerophytum humesi
Luu, P. V., Phan, T. T. T., Pham, N. T., Le, H. G., Chen, L. Y., Ton-Nu, H. L., Lee, M. H., Shen, Y. A., Fan, Y. J., Chang, Y. C., Su, J. H., Peng, B. R. & Lai, K. H., Jan 2026, In: Phytochemistry. 244, p. 114756 114756.Research output: Contribution to journal › Article › peer-review
4 Link opens in a new tab Citations (Scopus) -
Targeting glutamine metabolism combined with a nanoradioenhancer in radioresistant hepatocellular carcinoma
Kuo, C. C., Chuang, Y. C., Wu, P. H., Chang, W. M., Lo, L. W., Chen, H. Y., Lee, K. H., Lee, H. L., Chiou, J. F. & Shen, Y. A., 2026, (Accepted/In press) In: Nanoscale.Research output: Contribution to journal › Article › peer-review