Projects per year
Personal profile
Education
- 2009-2015 Ph.D., Institute of Biochemistry and Molecular Biology, National Yang Ming University
- 2007-2009 M.S., Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University
- 2000-2004 B.S., Department of Life Science, Tzu Chi University
Experience
- 2024.02- Associate Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
- 2024.02- Joint-Appointment Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2020.02-2024.01 Assistant Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2019.06-2024.01 Assistant Professor, Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University
- 2016.08-2019.06 Postdoctoral Research Fellow, Johns Hopkins University
- 2015.08-2016.08 Postdoctoral Research Fellow, National Yang-Ming University
- 2015.02-2015.07 Postdoctoral Research Fellow, Taipei Veterans General Hospital
Research Interests
- Translational Medicine, Cancer Stem Cell, Metabolism, Nanomedicine
Awards
- 2018.03.14 Pathology Award – 20th Annual Department of Pathology Young Investigators' Day, Johns Hopkins University, USA
- 2016.11.28 Postdoctoral Research Abroad Program (PRAP) Award – Ministry of Science and Technology, Taiwan
- 2013.11.06 Young Investigator Award – International Symsposium on Mitochondria 2013 / The 13th Conference of Japanese Society of Mitochondrial Research and Medicine (J-mit), Japan
- 2013.11.04 Young Investigator Award – 10th Conference of the Asian Society of Mitochondrial Research and Medicine (ASMRM), Korea
- 2013.10.19 First prize of Poster Award – 2013 Mini-symposium on Mitochondria and Aging, Taiwan
- 2013.10.16 Young Investigator Award – 6th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia), Taiwan
- 2013.09.07 Third Prize of Poster Award – 2013 International Symposium on Mitochondrial Dynamics in Translational Medicine, Taiwan
- 2012.11.02 Young Investigator Award – 2012 Conference of 9th ASMRM Beijing, China
- 2012.10.26 Silver Medal Award of Oral Session Competition – 7th International Symposium on Genomic Medicine of CCH, Taiwan
- 2011.10.07 Fellowships Award – 22nd FAOBMB Conference, Singapore
- 2011.08.31 Young Investigator Award – 2011 8th Conference of ASMRM in Kagoshima, Japan
- 2011.07.09 First prize of Poster Award – 2011 Mackay International Symposium on Mitochondrial Medicine in Human Health and Diseases in Taipei, Taiwan
- 2010.12.15 Young Investigator Award – 2010 7th Conference of ASMRM in Fukuoka, Japan
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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運用中孔洞二氧化矽奈米載體傳遞PBX1抑制劑克服吉西他濱所誘導抗藥性胰臟癌之癌幹細胞特性
Shen, Y.-A. (PI)
1/1/25 → 12/31/25
Project: A - Government Institution › a - National Health Research Institutes
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Utilizing Glucosamine-Labeled Nanodrugs as a Novel Pancreatic Cancer Stem Cell Therapy to Counteract Metabolic Compensation and Synergistically Inhibit Transcriptional Activity( I )
Shen, Y.-A. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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科研創業計畫：癌幹細胞篩選技術平台暨細胞療法開發之商業化應用
Shen, Y.-A. (PI)
1/1/24 → 12/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Investigation on the Synergistic Effect of a Combination of Pcsk9 Inhibitors and Hyperthermia in Hepatic Cancer Stem Cells
Shen, Y.-A. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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探討粒線體與內質網交互作用在大腸直腸癌幹細胞的調控機制
Shen, Y.-A. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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Cytotoxicity-guided isolation of elatostemanosides I-VI from Elatostema tenuicaudatum W. T. Wang and their cytotoxic activities
Huynh, Q. D. T., Phan, T. T. T., Liu, T. W., Duong, T. L. T., Hsu, S. J., Kuo, C. C., Chu, M. H., Wang, Y. H., Nguyen, T. V., Shen, Y. A., Fan, Y. J., Nguyen, D. K., Vo, T. H. & Lee, C. K., Apr 4 2025, In: RSC Advances. 15, 14, p. 10639-10652 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Active DNA Demethylase, TET1, Increases Oxidative Phosphorylation and Sensitizes Ovarian Cancer Stem Cells to Mitochondrial Complex I Inhibitor
Chen, L. Y., Shen, Y. A., Chu, L. H., Su, P. H., Wang, H. C., Weng, Y. C., Lin, S. F., Wen, K. C., Liew, P. L. & Lai, H. C., Jun 2024, In: Antioxidants. 13, 6, 735.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Association of glutaminase expression with immune-suppressive tumor microenvironment, clinicopathologic features, and clinical outcomes in endometrial cancer
Asaka, S., Verma, N., Yen, T. T., Hicks, J. L., Nonogaki, H., Shen, Y. A., Hong, J., Asaka, R., DeMarzo, A. M., Wang, T. L., Shih, I. M. & Gaillard, S., Nov 4 2024, In: International Journal of Gynecological Cancer. 34, 11, p. 1737-1744 8 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Fatty acid synthase inhibitor cerulenin hinders liver cancer stem cell properties through FASN/APP axis as novel therapeutic strategies
Chen, L. Y., Wu, D. S. & Shen, Y. A., Nov 2024, In: Journal of Lipid Research. 65, 11Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
PBX1 as a novel master regulator in cancer: Its regulation, molecular biology, and therapeutic applications
Kao, T. W., Chen, H. H., Lin, J., Wang, T. L. & Shen, Y. A., Mar 2024, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1879, 2, 189085.Research output: Contribution to journal › Review article › peer-review
Open Access7 Citations (Scopus)