Wen-Chang Chang

Projects

Projects per year 2011 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2025

• 2 Active
• 50 Finished

Projects per year

Search results

• Active

  Investigating the Metabolic Reprogramming-Derived Pd-L1 in Regulating Oncogenic Egfr Signaling-Associated Head and Neck Cancer Metastasis

  Chang, W.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• The Publication of Journal of Biomedical Science( I )

  Chang, W.-C. (PI)

  1/1/24 → 12/31/24

  Project: A - Government Institution › b - National Science and Technology Council
• Finished

  研究頭頸癌細胞內本質的細胞程序死亡配體一與代謝重編成誘導的癌轉移之間的相互作用

  Chang, W.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 脂肪酸代謝所調控的神經炎症在構建造成腫瘤復發之神經元-巨噬細胞-膠質瘤迴路中的角色－花生四烯酸代謝失調在神經元促進的神經膠質瘤復發中的角色(2/3)

  Chang, W.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 生醫科學雜誌規劃案(2/2)

  Chang, W.-C. (PI)

  1/1/23 → 12/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Role of Arnt/Pdk1 Axis in Chemotherapy-Associated Progression of Head and Neck Squamous Cell Carcinoma( III )

  Chang, W.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Role of Dysregulated Arachidonate Metabolism in Neuron-Promoted Glioblastoma Recurrence.( I )

  Chang, W.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/22 → 12/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Arachidonate Metabolism in Determining Ying-Yang Effects of Sp1 on Drug Resistance in Glioblastoma and Lung Cancer( III )

  Chang, W.-C. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Role of Arnt/Pdk1 Axis in Chemotherapy-Associated Progression of Head and Neck Squamous Cell Carcinoma( II )

  Chang, W.-C. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 《生醫科學雜誌》規劃案(2/2)

  Chang, W.-C. (PI)

  1/1/21 → 12/31/21

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Role of Arnt/Pdk1 Axis in Chemotherapy-Associated Progression of Head and Neck Squamous Cell Carcinoma( I )

  Chang, W.-C. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Arachidonate Metabolism in Determining Ying-Yang Effects of Sp1 on Drug Resistance in Glioblastoma and Lung Cancer( II )

  Chang, W.-C. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• The Publication of Journal of Biomedical Science(1/2)

  Chang, W.-C. (PI)

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - National Science and Technology Council

  • Publications 100%
  • Journals 100%

• A Tmu/Nih International Collaboration Study – Translational Research on Memory Reserve against Traumatic Brain Injury

  Chang, W.-C. (PI)

  10/1/19 → 12/31/20

  Project: A - Government Institution › b - National Science and Technology Council

  • Neurotrauma 100%
  • Traumatic Brain Injury 100%
  • Memory Disorder 30%
  • Functional Connectivity 20%
  • Connectomics 20%

• Characterization of Sp1-Dependent Dna Damage Response in Recurrent Glioblastoma

  Chang, W.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Arachidonate Metabolism in Determining Ying-Yang Effects of Sp1 on Drug Resistance in Glioblastoma and Lung Cancer( I )

  Chang, W.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• To Study the Role of Sp1 in Cancer Metastatic Progression(3/3)

  Chang, W.-C. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression(3/3)

  Chang, W.-C. (PI)

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Enzyme 100%
  • Oncogene 100%
  • Carcinogenesis 100%
  • Tumor Progression 100%
  • Digestant 100%

• 生醫科學雜誌規劃案(1/2)

  Chang, W.-C. (PI)

  1/1/18 → 12/31/18

  Project: A - Government Institution › b - National Science and Technology Council

• Neuroprotective Effects of Sig-1r-Znf179-Sp1 Pathway on Brain Injury

  Chang, W.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Brain Injury 100%
  • Sigma 1 Opiate Receptor 100%
  • Neuroprotective Agent 100%
  • Traumatic Brain Injury 88%
  • Neurotrauma 88%

• To Study the Role of Sp1 in Cancer Metastatic Progression( II )

  Chang, W.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression

  Chang, W.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Enzyme 100%
  • Oncogene 100%
  • Carcinogenesis 100%
  • Tumor Progression 100%
  • Digestant 100%

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/17 → 3/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Publications 100%
  • Journals 100%

• 生命科技相關科技發展計畫規劃、審議及管考諮詢之研究

  Chang, W.-C. (PI)

  1/1/17 → 12/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Development Project 100%
  • Technology 100%
  • Technological Development 66%
  • Committee Meeting 66%
  • Administrative Structure 40%

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression

  Chang, W.-C. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Enzyme 100%
  • Oncogene 100%
  • Carcinogenesis 100%
  • Tumor Progression 100%
  • Digestant 100%

• To Study the Role of Sp1 in Cancer Metastatic Progression( I )

  Chang, W.-C. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Tumor Progression 100%
  • Metastasis 100%
  • Malignant Neoplasm 100%
  • Neoplasm 80%
  • P53 66%

• 臺美(US)國合計畫－腦傷害的新診斷和新治療之轉譯研究－Sig-1R-Znf179-Sp1路徑在腦傷害之神經保護作用(2/3)

  Chang, W.-C. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Sigma 1 Opiate Receptor 100%
  • Neurotrauma 80%
  • Traumatic Brain Injury 80%
  • Hydrogen Peroxide 50%
  • Neuroprotective Agent 50%

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - National Science and Technology Council

• 生命科技群組政府科技發展計畫規劃及審議之研究

  Chang, W.-C. (PI)

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - National Science and Technology Council

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y. (PI), Whang-Peng, J. (CoI), Liu, L.-F. (CoI) & Chang, W.-C. (CoI)

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Magnetism 100%
  • Malignant Neoplasm 100%
  • Neoplasm 88%
  • Animal Model 80%
  • Cancer Cell 80%

• Neuroprotective Effects of Sig-1R-Znf179-Sp1 Pathway on Brain Injury

  Chang, W.-C. (PI) & Chuang, J.-Y. (CoI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Brain Injury 100%
  • Sigma 1 Opiate Receptor 100%
  • Neuroprotective Agent 100%
  • Traumatic Brain Injury 80%
  • Neurotrauma 80%

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.-C. (PI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Enzyme 100%
  • Protein Expression 100%
  • Cancer Cell 100%
  • Drug Resistance 100%
  • Phosphoinositide-Dependent Kinase-1 100%

• 生命科技群組政府科技發展計畫規劃及審議之研究

  Chang, W.-C. (PI)

  1/1/15 → 12/31/15

  Project: A - Government Institution › b - National Science and Technology Council

• 104年度「空中救護審核機制計畫」

  Tsai, S.-H. (PI), Whang-Peng, J. (CoI), Liu, L.-F. (CoI), Chang, W.-C. (CoI), Ho, Y.-S. (CoI), Cheng, Y.-W. (CoI), Yeh, S.-D. (CoI), Chen, K.-C. (CoI), Sung, S.-Y. (CoI), Hung, K.-S. (CoI), Chen, R.-M. (CoI), Chiou, H.-Y. (CoI), Chen, C.-Y. (CoI) & Li, Y.-C. (CoI)

  1/1/15 → 3/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/15 → 3/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Publications 100%
  • Journals 100%

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.-C. (PI)

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

  • Enzyme 100%
  • Drug Resistance 100%
  • Phosphoinositide-Dependent Kinase-1 100%
  • Protein Expression 100%
  • Growth Factor 100%

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury (III)

  Chang, W.-C. (PI)

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - National Science and Technology Council

  • Publications 100%
  • Journals 100%

• Role of Sp-family in lung tumorigenesis

  Chang, W.-C. (PI)

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

  • Lung Cancer 100%
  • Carcinogenesis 100%
  • Protein Family 100%
  • Lung Tumor 57%
  • Doxycycline 57%

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.-C. (PI)

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury (II)

  Chang, W.-C. (PI)

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

• The Publication of Journal of Biomedical Science (1/3)

  Chang, W.-C. (PI)

  1/1/13 → 2/28/14

  Project: A - Government Institution › b - National Science and Technology Council

  • Reviewed Journal 100%
  • Editorial Board 100%
  • Journal Report 100%
  • Electronic Format 100%
  • Research Information 100%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.-C. (PI)

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Lung Cancer 100%
  • Carcinogenesis 100%
  • Protein Family 100%
  • Lung Tumor 57%
  • Doxycycline 57%

• 轉錄因子Sp1在腦神經損傷所扮演隻角色(1/3)

  Chang, W.-C. (PI)

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury( I )

  Chang, W.-C. (PI)

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Sigma Receptor 100%
  • Sp1 Transcription Factor 100%
  • Animal Model 75%
  • Cell Level 50%
  • Internal Ribosome Entry Site 50%

• Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

  Chang, W.-C. (PI)

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Cancer Therapy 100%
  • Breast Tumor 100%
  • Tumor Progression 100%
  • Metastatic Carcinoma 100%
  • Tumor Growth 100%

• The Publication of Journal of Biomedical Science

  Chang, W.-C. (PI)

  1/1/12 → 2/28/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Publications 100%
  • Journals 100%

• The Differential Effect of Egf on the Induction of Cyclooxygenase-2 Expression in Squamous and Adenocarcinoma Cells

  Chang, W.-C. (PI)

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - National Science and Technology Council

  • Hypoxia Inducible Factor 1beta 100%
  • Cyclooxygenase 2 100%
  • Adenocarcinoma 100%
  • Cyclooxygenase 100%
  • Squamous Cell 60%