Projects per year
Personal profile
Education
- 1973-1976 Ph.D., Faculty of Pharmaceutical Sciences, University of Tokyo
- 1971-1973 M.S., Faculty of Pharmaceutical Sciences, University of Tokyo
- 1965-1969 B.S., School of Pharmacy, Taipei Medical College
Experience
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2014.07-2022.07 Chairman, Board of Trustees, Taipei Medical University
- 2013.02- The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2011.05- Chair Professor, Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University
- 2011- Emeritus Distinguished Chair Professor, National Cheng Kung University
- 2008.05-2011.05 Deputy Minister, National Science Council
- 2007-2011 Distinguished Chair Professor of National Cheng Kung University
- 2005-2008 Dean, College of Bioscience and Biotechnology, National Cheng Kung University
- 2004- Academician of Academia Sinica
- 2003-2008 Director, Center for Biosciences and Biotechnology, National Cheng Kung University
- 2001 University Chair Professor of National Cheng Kung University
- 1999.11-2001.08 General Director, Department of Life Sciences, National Science Council, Taiwan
- 1999 Visiting Professor, Biosignal Research Center, Kobe University, Japan
- 1998-1999 Associate Dean, College of Medical, Cheng Kung University
- 1997 Visiting Scholar, William Harvey Research Institute (Director Sir John R. Vane), London, U. K.
- 1994.10-1999.10 Chairman, Institute of Basic Medical Sciences, National Cheng Kung University
- 1983.10-2011.01 Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University
- 1983.10-1990.07 Chairman, Department of Pharmacology, National Cheng Kung University
- 1981.12-1983.09 Visiting Scientist, College of Pharmacy, University of Kentucky, U.S.A.
- 1979.01-1981.12 Visiting Scientist, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
- 1976.09-1978.12 Visiting Fellow, National Institute on Aging, NIH, Baltimore, Maryland, U.S.A.
Awards
- 2015, K. T. Lee’s Science and Technology Chair, Chair Professor
- 2011, Member of The Third World Academy of Sciences
- 2008, Life-long Honor of National Professorship, Ministry of Education, Taiwan
- 2006, The 16th Annual Wang Ming-Ning Award
- 2006, Phi Tau Phi Scholastic Honor Society, Outstanding Achievement Award and Honorary Members
- 2005, K. T. Lee’s Science and Technology Chair, Honorary Scholar Award
- 2004, APEX International Honor Society for Leadership, Honorary Member
- 2004, Academician of Academia Sinica
- 2004, Merit NSC Research Fellow Award, Taiwan
- 1999, 2004, National Professorship, Ministry of Education, Taiwan
- 1998, Science Academy Award, Ministry of Education, Taiwan
- 1997-2002, Distinguished Scientist, specially contracted with National Science Council, Taiwan
- 1996, Board Award, Chinese Education and Culture Foundation, Taiwan
- 1995, Glaxo-William Harvey Medical Award, Glaxo Co., Taiwan
- 1994, Distinguished Research Award, Chinese Pharmacological Society, Taiwan
- 1993, Wu San-Lien Award in Medical Science, Wu San-Lien Award Foundation, Taiwan
- 1986, 1988, 1991, 1993, Distinguished Research Award, National Science Council, Taiwan
Research Interests
- Prostaglandins
- Anti-Inflammation
- Signal Transduction
- Molecular Pharmacology
Fingerprint
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigating the Interplay between Fatty Acid Signaling and Egfr Activation in Regulating Head and Neck Cancer Metastasis and Therapy
Chang, W.-C. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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開發同時阻斷 CXCL8-CXCR1/2 訊號重編程 GAMs 及給予新抗原特異性 T 細胞受體工程性 T 細胞療法應用於膠質母細胞瘤(1/2)
Chang, W.-C. (PI)
9/1/24 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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The Publication of Journal of Biomedical Science( II )
Chang, W.-C. (PI)
1/1/25 → 12/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Metabolic Reprogramming-Derived Pd-L1 in Regulating Oncogenic Egfr Signaling-Associated Head and Neck Cancer Metastasis
Chang, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Role of Dysregulated Arachidonate Metabolism in Neuron-Promoted Glioblastoma Recurrence.( III )
Chang, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Contribution of Prostaglandin E2-Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative
Shen, C. J., Chen, H. C., Lin, C. L., Thakur, A., Onuku, R., Chen, I. C., Li, H. Y., Chang, K. Y., Chuang, J. Y., Yang, W. B., Lin, H. Y., Shen, Y. R., Liou, J. P., Chang, W. C. & Hsu, T. I., Oct 13 2025, In: Advanced Science. 12, 38, e06336.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Oleic acid-induced metastasis of KRAS/p53-mutant CRC relies on extracellular vesicles containing ICAM-1 and fibronectin
Shen, C.-J., Chang, W.-C. & Chen, B. K., Sept 2025.Research output: Contribution to conference › Poster › peer-review
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USP24 upregulation stabilizes PKA-Cα to promote lipogenesis, inflammation, and fibrosis during MASH progression
Ning, B., Wang, S. A., Young, M. J., Chen, Y. C., Hung, Y., Huong, T. T., Chang, W. C., Wang, Y. C., Yu, M. L., Hsu, K. C. & Hung, J. J., Dec 2025, In: Journal of Biomedical Science. 32, 1, 54.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function
Chen, C. H., Lin, H. W., Huang, M. F., Chiang, C. W., Lee, K. H., Phuong, N. T., Cai, Z. Y., Chang, W. C. & Lin, D. Y., Dec 2024, In: BMC Molecular and Cell Biology. 25, 1, 2.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
Shen, C.-J., Chan, R.-H., Lin, B.-W., Li, N.-C., Huang, Y.-H., Chang, W.-C. & Chen, B.-K., 2023, In: Theranostics. 13, 13, p. 4650-4666 17 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)
Datasets
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, K.-H. (Creator), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor), Chang, W.-C. (Creator), Shen, C.-K. J. (Contributor), Kao, T.-J. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Huang, W.-C. (Contributor) & Lin, H.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://doi.org/10.6084%2Fm9.figshare.7313777.v1
Dataset
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Additional file 2: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y.-C. (Creator), Lee, K.-H. (Creator), Shen, C.-K. J. (Contributor), Chang, W.-C. (Creator), Lin, J.-H. (Contributor), Huang, W.-C. (Contributor), Lin, H.-C. (Contributor), Lin, H.-C. (Contributor), Kao, T.-J. (Contributor) & Huang, C.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313798.v1, https://doi.org/10.6084%2Fm9.figshare.7313798.v1
Dataset
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Additional file 8: of V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients
Wu, M.-S. (Contributor), Chang, C.-M. (Creator), Liu, X. (Creator), Wong, H.S.-C. (Creator), Chang, W.-C. (Creator), Hsu, Y.-W. (Creator), Chang, W.-C. (Creator) & Kao, C.-C. (Contributor), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3824278_d8.v1, https://doi.org/10.6084%2Fm9.figshare.c.3824278_d8.v1
Dataset
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Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Lin, H.-C. (Contributor), Ching, Y.-H. (Contributor), Huang, C.-C. (Contributor), Pao, P.-C. (Contributor), Lee, Y.-H. (Creator), Chang, W.-C. (Creator), Kao, T.-J. (Contributor) & Lee, Y.-C. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4486100.v1, https://doi.org/10.6084%2Fm9.figshare.c.4486100.v1
Dataset
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Additional file 1: of Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Ching, Y.-H. (Contributor), Lee, Y.-H. (Creator), Lee, Y.-C. (Creator), Huang, C.-C. (Contributor), Lin, H.-C. (Contributor), Chang, W.-C. (Creator), Kao, T.-J. (Contributor) & Pao, P.-C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8050076.v1, https://doi.org/10.6084%2Fm9.figshare.8050076.v1
Dataset