Projects per year
Personal profile
Education
- 1973-1976 Ph.D., Faculty of Pharmaceutical Sciences, University of Tokyo
- 1971-1973 M.S., Faculty of Pharmaceutical Sciences, University of Tokyo
- 1965-1969 B.S., School of Pharmacy, Taipei Medical College
Experience
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2014.07-2022.07 Chairman, Board of Trustees, Taipei Medical University
- 2013.02- The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2011.05- Chair Professor, Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University
- 2011- Emeritus Distinguished Chair Professor, National Cheng Kung University
- 2008.05-2011.05 Deputy Minister, National Science Council
- 2007-2011 Distinguished Chair Professor of National Cheng Kung University
- 2005-2008 Dean, College of Bioscience and Biotechnology, National Cheng Kung University
- 2004- Academician of Academia Sinica
- 2003-2008 Director, Center for Biosciences and Biotechnology, National Cheng Kung University
- 2001 University Chair Professor of National Cheng Kung University
- 1999.11-2001.08 General Director, Department of Life Sciences, National Science Council, Taiwan
- 1999 Visiting Professor, Biosignal Research Center, Kobe University, Japan
- 1998-1999 Associate Dean, College of Medical, Cheng Kung University
- 1997 Visiting Scholar, William Harvey Research Institute (Director Sir John R. Vane), London, U. K.
- 1994.10-1999.10 Chairman, Institute of Basic Medical Sciences, National Cheng Kung University
- 1983.10-2011.01 Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University
- 1983.10-1990.07 Chairman, Department of Pharmacology, National Cheng Kung University
- 1981.12-1983.09 Visiting Scientist, College of Pharmacy, University of Kentucky, U.S.A.
- 1979.01-1981.12 Visiting Scientist, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
- 1976.09-1978.12 Visiting Fellow, National Institute on Aging, NIH, Baltimore, Maryland, U.S.A.
Awards
- 2015, K. T. Lee’s Science and Technology Chair, Chair Professor
- 2011, Member of The Third World Academy of Sciences
- 2008, Life-long Honor of National Professorship, Ministry of Education, Taiwan
- 2006, The 16th Annual Wang Ming-Ning Award
- 2006, Phi Tau Phi Scholastic Honor Society, Outstanding Achievement Award and Honorary Members
- 2005, K. T. Lee’s Science and Technology Chair, Honorary Scholar Award
- 2004, APEX International Honor Society for Leadership, Honorary Member
- 2004, Academician of Academia Sinica
- 2004, Merit NSC Research Fellow Award, Taiwan
- 1999, 2004, National Professorship, Ministry of Education, Taiwan
- 1998, Science Academy Award, Ministry of Education, Taiwan
- 1997-2002, Distinguished Scientist, specially contracted with National Science Council, Taiwan
- 1996, Board Award, Chinese Education and Culture Foundation, Taiwan
- 1995, Glaxo-William Harvey Medical Award, Glaxo Co., Taiwan
- 1994, Distinguished Research Award, Chinese Pharmacological Society, Taiwan
- 1993, Wu San-Lien Award in Medical Science, Wu San-Lien Award Foundation, Taiwan
- 1986, 1988, 1991, 1993, Distinguished Research Award, National Science Council, Taiwan
Research Interests
- Prostaglandins
- Anti-Inflammation
- Signal Transduction
- Molecular Pharmacology
Fingerprint
Dive into the research topics where Wen-Chang Chang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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研究頭頸癌細胞內本質的細胞程序死亡配體一與代謝重編成誘導的癌轉移之間的相互作用
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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脂肪酸代謝所調控的神經炎症在構建造成腫瘤復發之神經元-巨噬細胞-膠質瘤迴路中的角色－花生四烯酸代謝失調在神經元促進的神經膠質瘤復發中的角色(2/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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生醫科學雜誌規劃案(2/2)
1/1/23 → 12/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Role of Dysregulated Arachidonate Metabolism in Neuron-Promoted Glioblastoma Recurrence.( I )
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Role of Arnt/Pdk1 Axis in Chemotherapy-Associated Progression of Head and Neck Squamous Cell Carcinoma( III )
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance
Lin, H. Y., Lim, S. W., Hsu, T. I., Yang, W. B., Huang, C. C., Tsai, Y. T., Chang, W. C. & Ko, C. Y., 2022, In: Oxidative Medicine and Cellular Longevity. 2022, 4081380.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers
Hsiao, Y. W., Chi, J. Y., Li, C. F., Chen, L. Y., Chen, Y. T., Liang, H. Y., Lo, Y. C., Hong, J. Y., Chuu, C. P., Hung, L. Y., Du, J. Y., Chang, W. C. & Wang, J. M., Jan 2022, In: Clinical and Translational Medicine. 12, 1, e724.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Estradiol-mediated inhibition of DNMT1 decreases p53 expression to induce M2-macrophage polarization in lung cancer progression
Chen, Y. C., Young, M. J., Chang, H. P., Liu, C. Y., Lee, C. C., Tseng, Y. L., Wang, Y. C., Chang, W. C. & Hung, J. J., Dec 2022, In: Oncogenesis. 11, 1, 25.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression
Young, M. J., Chen, Y. C., Wang, S. A., Chang, H. P., Yang, W. B., Lee, C. C., Liu, C. Y., Tseng, Y. L., Wang, Y. C., Sun, H. S., Chang, W. C. & Hung, J. J., Jan 17 2022, In: Journal of Biomedical Science. 29, 1, p. 3 3.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells
Wu, A. C., Yang, W. B., Chang, K. Y., Lee, J. S., Liou, J. P., Su, R. Y., Cheng, S. M., Hwang, D. Y., Kikkawa, U., Hsu, T. I., Wang, C. Y., Chang, W. C., Chen, P. Y. & Chuang, J. Y., Dec 2022, In: Journal of Experimental and Clinical Cancer Research. 41, 1, 47.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus)
Datasets
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Additional file 2: of Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Kao, T. (Contributor), Pao, P. (Contributor), Huang, C. (Contributor), Lee, Y. (Creator), Ching, Y. (Contributor), Chang, W. (Creator), Lin, H. (Contributor) & Lee, Y. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.8050079.v1, https://doi.org/10.6084%2Fm9.figshare.8050079.v1
Dataset
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Additional file 6: of V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients
Wu, M. (Contributor), Chang, W. (Creator), Kao, C. (Contributor), Hsu, Y. (Creator), Chang, W. (Creator), Chang, C. (Creator), Liu, X. (Creator) & Wong, H. S. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3824278_d6.v1, https://doi.org/10.6084%2Fm9.figshare.c.3824278_d6.v1
Dataset
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Additional file 1: of Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Ching, Y. (Contributor), Lee, Y. (Creator), Lee, Y. (Creator), Huang, C. (Contributor), Lin, H. (Contributor), Chang, W. (Creator), Kao, T. (Contributor) & Pao, P. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8050076.v1, https://doi.org/10.6084%2Fm9.figshare.8050076.v1
Dataset
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Additional file 1: of Suberoylanilide hydroxamic acid represses glioma stem-like cells
Chang, K. (Creator), Wang, J. (Creator), Chuang, J. (Creator), Ko, C. (Contributor), Hsu, T. (Contributor), Chang, W. (Creator), Yeh, S. (Contributor), Liou, J. (Creator), Liu, J. (Contributor) & Hsu, C. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3596465_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465_d1.v1
Dataset
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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y. (Creator), Lo, W. (Creator), Chen, P. (Creator), Ko, C. (Creator), Chuang, J. (Creator), Kao, T. (Creator), Yang, W. (Creator), Chang, K. (Creator), Hung, C. (Creator), Kikkawa, U. (Creator), Chang, W. (Creator) & Hsu, T. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1
Dataset