Projects per year
Personal profile
Education
- 1973-1976 Ph.D., Faculty of Pharmaceutical Sciences, University of Tokyo
- 1971-1973 M.S., Faculty of Pharmaceutical Sciences, University of Tokyo
- 1965-1969 B.S., School of Pharmacy, Taipei Medical College
Experience
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2014.07-2022.07 Chairman, Board of Trustees, Taipei Medical University
- 2013.02- The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2011.05- Chair Professor, Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University
- 2011- Emeritus Distinguished Chair Professor, National Cheng Kung University
- 2008.05-2011.05 Deputy Minister, National Science Council
- 2007-2011 Distinguished Chair Professor of National Cheng Kung University
- 2005-2008 Dean, College of Bioscience and Biotechnology, National Cheng Kung University
- 2004- Academician of Academia Sinica
- 2003-2008 Director, Center for Biosciences and Biotechnology, National Cheng Kung University
- 2001 University Chair Professor of National Cheng Kung University
- 1999.11-2001.08 General Director, Department of Life Sciences, National Science Council, Taiwan
- 1999 Visiting Professor, Biosignal Research Center, Kobe University, Japan
- 1998-1999 Associate Dean, College of Medical, Cheng Kung University
- 1997 Visiting Scholar, William Harvey Research Institute (Director Sir John R. Vane), London, U. K.
- 1994.10-1999.10 Chairman, Institute of Basic Medical Sciences, National Cheng Kung University
- 1983.10-2011.01 Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University
- 1983.10-1990.07 Chairman, Department of Pharmacology, National Cheng Kung University
- 1981.12-1983.09 Visiting Scientist, College of Pharmacy, University of Kentucky, U.S.A.
- 1979.01-1981.12 Visiting Scientist, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
- 1976.09-1978.12 Visiting Fellow, National Institute on Aging, NIH, Baltimore, Maryland, U.S.A.
Awards
- 2015, K. T. Lee’s Science and Technology Chair, Chair Professor
- 2011, Member of The Third World Academy of Sciences
- 2008, Life-long Honor of National Professorship, Ministry of Education, Taiwan
- 2006, The 16th Annual Wang Ming-Ning Award
- 2006, Phi Tau Phi Scholastic Honor Society, Outstanding Achievement Award and Honorary Members
- 2005, K. T. Lee’s Science and Technology Chair, Honorary Scholar Award
- 2004, APEX International Honor Society for Leadership, Honorary Member
- 2004, Academician of Academia Sinica
- 2004, Merit NSC Research Fellow Award, Taiwan
- 1999, 2004, National Professorship, Ministry of Education, Taiwan
- 1998, Science Academy Award, Ministry of Education, Taiwan
- 1997-2002, Distinguished Scientist, specially contracted with National Science Council, Taiwan
- 1996, Board Award, Chinese Education and Culture Foundation, Taiwan
- 1995, Glaxo-William Harvey Medical Award, Glaxo Co., Taiwan
- 1994, Distinguished Research Award, Chinese Pharmacological Society, Taiwan
- 1993, Wu San-Lien Award in Medical Science, Wu San-Lien Award Foundation, Taiwan
- 1986, 1988, 1991, 1993, Distinguished Research Award, National Science Council, Taiwan
Research Interests
- Prostaglandins
- Anti-Inflammation
- Signal Transduction
- Molecular Pharmacology
Fingerprint
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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生醫科學雜誌規劃案(2/2)
Chang, W.-C. (PI)
1/1/25 → 12/31/25
Project: A - Government Institution › b - National Science and Technology Council
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開發同時阻斷 CXCL8-CXCR1/2 訊號重編程 GAMs 及給予新抗原特異性 T 細胞受體工程性 T 細胞療法應用於膠質母細胞瘤(1/2)
Chang, W.-C. (PI)
9/1/24 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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Role of Dysregulated Arachidonate Metabolism in Neuron-Promoted Glioblastoma Recurrence.( III )
Chang, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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脂肪酸代謝所調控的神經炎症在構建造成腫瘤復發之神經元-巨噬細胞-膠質瘤迴路中的角色－花生四烯酸代謝失調在神經元促進的神經膠質瘤復發中的角色(3/3)
Chang, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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研究代謝重編成衍生的細胞程序死亡配體1調節致癌表皮生長因子受體訊號有關的頭頸癌轉移
Chang, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function
Chen, C. H., Lin, H. W., Huang, M. F., Chiang, C. W., Lee, K. H., Phuong, N. T., Cai, Z. Y., Chang, W. C. & Lin, D. Y., Dec 2024, In: BMC Molecular and Cell Biology. 25, 1, 2.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
Shen, C.-J., Chan, R.-H., Lin, B.-W., Li, N.-C., Huang, Y.-H., Chang, W.-C. & Chen, B.-K., 2023, In: Theranostics. 13, 13, p. 4650-4666 17 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities
Chen, H. C., Chang, W. C., Chuang, J. Y., Chang, K. Y., Liou, J. P. & Hsu, T. I., Sept 2023, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1878, 5, 188957.Research output: Contribution to journal › Review article › peer-review
3 Citations (Scopus) -
CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance
Lin, H. Y., Lim, S. W., Hsu, T. I., Yang, W. B., Huang, C. C., Tsai, Y. T., Chang, W. C. & Ko, C. Y., 2022, In: Oxidative Medicine and Cellular Longevity. 2022, 4081380.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (Scopus) -
Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers
Hsiao, Y. W., Chi, J. Y., Li, C. F., Chen, L. Y., Chen, Y. T., Liang, H. Y., Lo, Y. C., Hong, J. Y., Chuu, C. P., Hung, L. Y., Du, J. Y., Chang, W. C. & Wang, J. M., Jan 2022, In: Clinical and Translational Medicine. 12, 1, e724.Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (Scopus)
Datasets
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, K.-H. (Creator), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor), Chang, W.-C. (Creator), Shen, C.-K. J. (Contributor), Kao, T.-J. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Huang, W.-C. (Contributor) & Lin, H.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://doi.org/10.6084%2Fm9.figshare.7313777.v1
Dataset
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Additional file 2: of Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Kao, T.-J. (Contributor), Pao, P.-C. (Contributor), Huang, C.-C. (Contributor), Lee, Y.-H. (Creator), Ching, Y.-H. (Contributor), Chang, W.-C. (Creator), Lin, H.-C. (Contributor) & Lee, Y.-C. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.8050079.v1, https://doi.org/10.6084%2Fm9.figshare.8050079.v1
Dataset
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Additional file 3: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Shen, C.-K. J. (Contributor), Lin, H.-C. (Contributor), Lee, K.-H. (Creator), Huang, W.-C. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Kao, T.-J. (Contributor), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor) & Chang, W.-C. (Creator), Figshare, 2018
DOI: 10.6084/m9.figshare.7313816.v1, https://doi.org/10.6084%2Fm9.figshare.7313816.v1
Dataset
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Additional file 1: of Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Ching, Y.-H. (Contributor), Lee, Y.-H. (Creator), Lee, Y.-C. (Creator), Huang, C.-C. (Contributor), Lin, H.-C. (Contributor), Chang, W.-C. (Creator), Kao, T.-J. (Contributor) & Pao, P.-C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8050076.v1, https://doi.org/10.6084%2Fm9.figshare.8050076.v1
Dataset
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Additional file 6: of V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients
Wu, M.-S. (Contributor), Chang, W.-C. (Creator), Kao, C.-C. (Contributor), Hsu, Y.-W. (Creator), Chang, W.-C. (Creator), Chang, C.-M. (Creator), Liu, X. (Creator) & Wong, H.S.-C. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3824278_d6.v1, https://doi.org/10.6084%2Fm9.figshare.c.3824278_d6.v1
Dataset