Projects per year
Personal profile
Education
- 2002 Ph. D., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
- 1995 M. S., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
- 1992 B. S., School of Pharmacy, Taipei Medical University
Experience
- 2019.11- Professor , Department of Pharmaceutical Sciences, Taipei Medical University
- 2019.08- Director, Department of Pharmaceutical Sciences, Taipei Medical University
- 2017.08- Professor, Graduate Institute of Pharmacognosy, Taipei Medical Universit
- 2013.08- Ph.D. Program in Clinical Drug Development of Herbal Medicine, Taipei Medical University
- 2011.08-2017.07 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
- 2007.08-2011.07 Assistant Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
- 2004.08-2007.07 Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Chiayi campus, Taiwan.
- 2003.09-2004.07 Postdoctoral Fellow, Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
- 2002.08-2003.08 Postdoctoral Fellow, Drug Research Center, National Taiwan University, Taipei, Taiwan
Research Interests
- Total synthesis and chemical modification of naturalproduct
- Development of natural product scaffold
- Structure-based drug design
- Microwave-assisted organic synthesis
Fingerprint
Dive into the research topics where Wei-Jan Huang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 19 Finished
-
結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(3/3)
Huang, W.-J. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
-
Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents (2/3)
Huang, W.-J. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
-
Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents
Huang, W.-J. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
-
Development of Protein Disulfide Isomerase Inhibitors That Target Glioblastoma Multiforme
Huang, W.-J. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
-
新穎小分子抗多發性骨髓瘤藥物機轉研究
Huang, W.-J. (PI)
7/1/20 → 2/1/21
Project: A - Government Institution › b - National Science and Technology Council
-
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., Jun 2024, In: Protein Science. 33, 6, e5007.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress
Wu, L. H., Cheng, Y. W., Lin, F. L., Hsu, K. C., Wang, M. H., Yen, J. L., Wang, T. J., Lin, T. E., Liu, Y. C., Huang, W. J. & Hsiao, G., May 2024, In: Biomedicine and Pharmacotherapy. 174, 116538.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Synthesis and biological evaluation of ortho-phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases
Hsu, K. C., Huang, Y. Y., Chu, J. C., Huang, Y. W., Hu, J. L., Lin, T. E., Yen, S. C., Weng, J. R. & Huang, W. J., 2024, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 39, 1, 2406025.Research output: Contribution to journal › Article › peer-review
Open Access -
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors
Hsu, J. Y., Hsu, K. C., Sun, C., Chou, C. H., Lin, T. E., Sung, T. Y., Tseng, H. J., Yen, S. C., Yang, C. R. & Huang, W. J., Mar 2023, In: Biomedicine and Pharmacotherapy. 159, 114258.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
New Synthesized Activating Transcription Factor 3 Inducer SW20.1 Suppresses Resistin-Induced Metabolic Syndrome
Tran, T. T., Huang, W. J., Lin, H. & Chen, H. H., Jun 2023, In: Biomedicines. 11, 6, 1509.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
-
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
Dataset
-
Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Yeh, Y.-L. (Creator), Wang, Y.-J. (Contributor), Chiu, H.-W. (Creator), Ho, S.-Y. (Contributor), Wang, Y.-C. (Contributor), Lin, P. (Contributor) & Huang, W.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276_d1.v1
Dataset
-
Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Chiu, H.-W. (Creator), Yeh, Y.-L. (Creator), Wang, Y.-C. (Contributor), Huang, W.-J. (Contributor), Ho, S.-Y. (Contributor), Lin, P. (Contributor) & Wang, Y.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1
Dataset