Projects per year
Personal profile
Education
- 2002 Ph. D., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
- 1995 M. S., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
- 1992 B. S., School of Pharmacy, Taipei Medical University
Experience
- 2019.11- Professor , Department of Pharmaceutical Sciences, Taipei Medical University
- 2019.08- Director, Department of Pharmaceutical Sciences, Taipei Medical University
- 2017.08- Professor, Graduate Institute of Pharmacognosy, Taipei Medical Universit
- 2013.08- Ph.D. Program in Clinical Drug Development of Herbal Medicine, Taipei Medical University
- 2011.08-2017.07 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
- 2007.08-2011.07 Assistant Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
- 2004.08-2007.07 Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Chiayi campus, Taiwan.
- 2003.09-2004.07 Postdoctoral Fellow, Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
- 2002.08-2003.08 Postdoctoral Fellow, Drug Research Center, National Taiwan University, Taipei, Taiwan
Research Interests
- Total synthesis and chemical modification of naturalproduct
- Development of natural product scaffold
- Structure-based drug design
- Microwave-assisted organic synthesis
Fingerprint
- 1 Similar Profiles
Network
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Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents (2/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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開發蛋白質雙硫鍵異構酶抑制劑作為抗多形性神經膠質母細胞瘤藥物
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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新穎小分子抗多發性骨髓瘤藥物機轉研究
7/1/20 → 2/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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Discovery of Multitarget Agents That Target Alzheimer'S Disease
8/1/19 → 7/31/20
Project: A - Government Institution › b - Ministry of Science and Technology
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Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors
Hsu, J. Y., Hsu, K. C., Sun, C., Chou, C. H., Lin, T. E., Sung, T. Y., Tseng, H. J., Yen, S. C., Yang, C. R. & Huang, W. J., Mar 2023, In: Biomedicine and Pharmacotherapy. 159, 114258.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
1,2,3,4,6-Penta-O-galloyl-D-glucose Interrupts the Early Adipocyte Lifecycle and Attenuates Adiposity and Hepatic Steatosis in Mice with Diet-Induced Obesity
Sathyanarayana, A. R., Lu, C. K., Liaw, C. C., Chang, C. C., Han, H. Y., Green, B. D., Huang, W. J., Huang, C., He, W. D., Lee, L. C. & Liu, H. K., Apr 1 2022, In: International journal of molecular sciences. 23, 7, 4052.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment
Lin, T. E., Yang, C. R., Chou, C. H., Hsu, J. Y., Chao, M. W., Sung, T. Y., Hsieh, J. H., Huang, W. J. & Hsu, K. C., Feb 2022, In: Biomedicine and Pharmacotherapy. 146, 112459.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach
Yen, S. C., Chen, L. C., Huang, H. L., HuangFu, W. C., Chen, Y. Y., Eight Lin, T., Lien, S. T., Tseng, H. J., Sung, T. Y., Hsieh, J. H., Huang, W. J., Pan, S. L. & Hsu, K. C., Apr 2022, In: Bioorganic Chemistry. 121, p. 105675 105675.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia
Yen, S. C., Wu, Y. W., Huang, C. C., Chao, M. W., Tu, H. J., Chen, L. C., Lin, T. E., Sung, T. Y., Tseng, H. J., Chu, J. C., Huang, W. J., Yang, C. R., HuangFu, W. C., Pan, S. L. & Hsu, K. C., Jun 2022, In: Phytomedicine. 100, 154061.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus)
Datasets
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M. (Creator), Lin, T. E. (Creator), HuangFu, W. (Creator), Chang, C. (Creator), Tu, H. (Creator), Chen, L. (Creator), Yen, S. (Creator), Sung, T. (Creator), Huang, W. (Creator), Yang, C. (Creator), Pan, S. (Creator) & Hsu, K. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
Dataset
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Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Chiu, H. (Creator), Yeh, Y. (Creator), Wang, Y. (Contributor), Huang, W. (Contributor), Ho, S. (Contributor), Lin, P. (Contributor) & Wang, Y. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1
Dataset
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Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Yeh, Y. (Creator), Wang, Y. (Contributor), Chiu, H. (Creator), Ho, S. (Contributor), Wang, Y. (Contributor), Lin, P. (Contributor) & Huang, W. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276_d1.v1
Dataset