Projects per year
Personal profile
Education
- 2002 Ph. D., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
- 1995 M. S., School of Pharmacy, National Taiwan University, Taipei, Organic Synthesis and Medicinal Chemistry
- 1992 B. S., School of Pharmacy, Taipei Medical University
Experience
- 2019.11- Professor , Department of Pharmaceutical Sciences, Taipei Medical University
- 2019.08- Director, Department of Pharmaceutical Sciences, Taipei Medical University
- 2017.08- Professor, Graduate Institute of Pharmacognosy, Taipei Medical Universit
- 2013.08- Ph.D. Program in Clinical Drug Development of Herbal Medicine, Taipei Medical University
- 2011.08-2017.07 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
- 2007.08-2011.07 Assistant Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taipei, Taiwan.
- 2004.08-2007.07 Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Chiayi campus, Taiwan.
- 2003.09-2004.07 Postdoctoral Fellow, Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
- 2002.08-2003.08 Postdoctoral Fellow, Drug Research Center, National Taiwan University, Taipei, Taiwan
Research Interests
- Total synthesis and chemical modification of naturalproduct
- Development of natural product scaffold
- Structure-based drug design
- Microwave-assisted organic synthesis
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Design and Synthesis of Novel Cyclin-Dependent Kinase 8 (Cdk8) Inhibitors as Potential Lead Compounds for Idiopathic Pulmonary Fibrosis
Huang, W.-J. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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探索新穎可逆性蛋白質雙硫鍵異構酶抑 制劑
Huang, W.-J. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents
Huang, W.-J. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents (2/3)
Huang, W.-J. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Structural Optimization of Phenylpropiolamide-Based Inhibitors of Protein Disulfide Isomerase as Potential Anti-Glioblastoma Multiforme Agents
Huang, W.-J. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma
Lee, K. L., Liu, J. J., Huang, W. J., Hung, C. S. & Liang, Y. C., Dec 2025, In: Cancer Cell International. 25, 1, 56.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase
Chu, J. C., Tsai, K. C., Wang, T. Y., Chen, T. Y., Tsai, J. Y., Lee, T., Lin, M. H., Hsieh, Y. S. Y., Wu, C. C. & Huang, W. J., Feb 5 2025, In: European Journal of Medicinal Chemistry. 283, p. 117169 117169.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening
Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., Jan 13 2025, In: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural optimization and biological evaluation of indolin-2-one derivatives as novel CDK8 inhibitors for idiopathic pulmonary fibrosis
Hsu, J. Y., Hsu, K. C., Chou, C. H., He, T. Y., Lin, T. E., Sung, T. Y., Yen, S. C., Hsieh, J. H., Yang, C. R. & Huang, W. J., Mar 2025, In: Biomedicine and Pharmacotherapy. 184, 117891.Research output: Contribution to journal › Article › peer-review
Open Access -
The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo
Chou, C. H., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E. & Yang, C. R., 2025, In: International Journal of Biological Sciences. 21, 2, p. 685-707 23 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Yeh, Y.-L. (Creator), Wang, Y.-J. (Contributor), Chiu, H.-W. (Creator), Ho, S.-Y. (Contributor), Wang, Y.-C. (Contributor), Lin, P. (Contributor) & Huang, W.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276_d1.v1
Dataset
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Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Chiu, H.-W. (Creator), Yeh, Y.-L. (Creator), Wang, Y.-C. (Contributor), Huang, W.-J. (Contributor), Ho, S.-Y. (Contributor), Lin, P. (Contributor) & Wang, Y.-J. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1
Dataset
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
Dataset