Projects per year
Personal profile
Education
- 1991 Post Doctor visitin, MAYO medical center, USA
- 1985 Medical PhD, National Medical Defence Center (MDMC)
- 1982 Pathology master, National Medical Defence Center (MDMC)
- 1978 medicine, National Medical Defence Center (MDMC)
Experience
- 2015 Professor, Medicine, and Pathology, TMU, and Director, Department of Medical Research, and Chief of Pathology, SHH, TMU
- 2008 Professor, Institue of injury & prevention, TMU, and Director, Department of Education & Research, and Chief of Pathology, SHH, TMU
- 2006 vice director, department of medical affairs, Wang-Fong hospital, TMU
- 1991 Professor & Dean, Institute of pathology, NDMC, Director of pathology, Tri-service General Hospital
Awards
- 2015 pass no concen accrediation of AAHRPP, received great achivement reward of SHH
Research Interests
- Pathology, Experimental Pathology, Molecular Pathology, Cell culture, Stem cell study, Chromosom analysis and FISH study of Hematologic Oncology , Forensic Medicine
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 6 Finished
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A Translational Investigation of the Role of Manganese Superoxide Dismutase (Mnsod) in M2-Macrophages for Colon Cancer Stem Cell Generation and Preclinical Evaluation of Mndso Modulators for Potential Colorectal Cancer Therapeutics
Lee, W.-H. (PI)
8/1/16 → 7/31/17
Project: A - Government Institution › b - National Science and Technology Council
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探討錳超氧化物歧化酶MnSOD抑制劑在調控腫瘤相關巨噬細胞及治療大腸癌之轉譯研究
Lee, W.-H. (PI)
6/1/16 → 5/31/17
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer
Wang, L.-S. (PI), Lee, W.-H. (CoI), Ho, Y.-S. (CoI) & Wu, A. T. (CoI)
8/1/15 → 7/31/16
Project: A - Government Institution › b - National Science and Technology Council
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Preclinical Assessment of the Potential Prognostic and Therapeutic Values of Hippo Signaling Cascade in Targeting Therapy-Resistant Cancer Stem Cells in Hepatocellular Carcinoma
Lee, W.-H. (PI)
8/1/13 → 7/31/14
Project: A - Government Institution › b - National Science and Technology Council
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探討Annexin A1/NF-kB axis 對於肝癌抗藥性及侵犯轉移之影響
Lee, W.-H. (PI)
5/1/13 → 12/31/14
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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Notopterol mitigates IL-1β-triggered pyroptosis by blocking NLRP3 inflammasome via the JAK2/NF-kB/hsa-miR-4282 route in osteoarthritis
Chen, K. T., Yeh, C. T., Yadav, V. K., Pikatan, N. W., Fong, I. H., Lee, W. H. & Chiu, Y. S., Mar 30 2024, In: Heliyon. 10, 6, e28094.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Correction to: Hydroxychloroquine (HCQ) Modulates Autophagy and Oxidative DNA Damage Stress in Hepatocellular Carcinoma to Overcome Sorafenib Resistance via TLR9/SOD1/hsa-miR-30a-5p/Beclin-1 Axis (Cancers, (2021), 13, 13, (3227), 10.3390/cancers13133227)
Chen, M. Y., Yadav, V. K., Chu, Y. C., Ong, J. R., Huang, T. Y., Lee, K. F., Lee, K. H., Yeh, C. T. & Lee, W. H., Feb 2023, In: Cancers. 15, 4, 1028.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis
Lai, S. W., Cheng, Y. C., Huang, W. C., Yadav, V. K., Fong, I. H., Yeh, C. T., Yang, C. K., Lee, W. H. & Chen, M. Y., 2023, In: Aging. 15, 20, p. 11033-11051 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cancer-Associated Exosomal CBFB Facilitates the Aggressive Phenotype, Evasion of Oxidative Stress, and Preferential Predisposition to Bone Prometastatic Factor of Breast Cancer Progression
Hsu, C. H., Ma, H. P., Ong, J. R., Hsieh, M. S., Yadav, V. K., Yeh, C. T., Chao, T. Y., Lee, W. H., Huang, W. C., Kuo, K. T., Fong, I. H., Lin, C. C. & Su, C. M., 2022, In: Disease Markers. 2022, 8446629.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
HNMT Upregulation Induces Cancer Stem Cell Formation and Confers Protection against Oxidative Stress through Interaction with HER2 in Non‐Small‐Cell Lung Cancer
Kuo, K. T., Lin, C. H., Wang, C. H., Pikatan, N. W., Yadav, V. K., Fong, I. H., Yeh, C. T., Lee, W. H. & Huang, W. C., Feb 1 2022, In: International journal of molecular sciences. 23, 3, 1663.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (Scopus)
Datasets
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Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
Kuo, K.-T. (Contributor), Huang, W.-C. (Contributor), Bamodu, O. A. (Contributor), Lee, W.-H. (Contributor), Wang, C.-H. (Creator), Hsiao, M. (Contributor), Wang, L.-S. (Creator) & Yeh, C.-T. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4194263.v1, https://figshare.com/collections/Histone_demethylase_JARID1B_KDM5B_promotes_aggressiveness_of_non-small_cell_lung_cancer_and_serves_as_a_good_prognostic_predictor/4194263/1
Dataset
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Additional file 3: of Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
Kuo, K.-T. (Contributor), Huang, W.-C. (Contributor), Bamodu, O. (Contributor), Lee, W.-H. (Contributor), Wang, C.-H. (Contributor), Hsiao, M. (Contributor), Wang, L.-S. (Contributor) & Yeh, C.-T. (Contributor), Unknown Publisher, Aug 9 2018
DOI: 10.6084/m9.figshare.6953543.v1, https://springernature.figshare.com/articles/Additional_file_3_of_Histone_demethylase_JARID1B_KDM5B_promotes_aggressiveness_of_non-small_cell_lung_cancer_and_serves_as_a_good_prognostic_predictor/6953543/1
Dataset
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Additional file 2: Figure S1. of Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
Yeh, C.-T. (Contributor), Huang, W.-C. (Contributor), Wu, A. (Creator), Bamodu, O. A. (Contributor), Lee, W.-H. (Contributor), Wang, L. S. (Creator), Chao, T.-Y. (Contributor) & Hsiao, M. (Creator), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3621719_d3.v1, https://doi.org/10.6084%2Fm9.figshare.c.3621719_d3.v1
Dataset
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Additional file 2: of Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
Kuo, K.-T. (Contributor), Huang, W.-C. (Contributor), Bamodu, O. (Contributor), Lee, W.-H. (Contributor), Wang, C.-H. (Contributor), Hsiao, M. (Contributor), Wang, L.-S. (Contributor) & Yeh, C.-T. (Contributor), Unknown Publisher, Aug 9 2018
DOI: 10.6084/m9.figshare.6953528.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Histone_demethylase_JARID1B_KDM5B_promotes_aggressiveness_of_non-small_cell_lung_cancer_and_serves_as_a_good_prognostic_predictor/6953528/1
Dataset
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Additional file 3: Figure S2. of Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
Hsiao, M. (Creator), Yeh, C.-T. (Contributor), Wu, A. (Creator), Wang, L. S. (Creator), Bamodu, O. A. (Contributor), Lee, W.-H. (Contributor), Chao, T.-Y. (Contributor) & Huang, W.-C. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3621719_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3621719_d2.v1
Dataset