Projects per year
Personal profile
Education
- 2007 Ph.D., Molecular and Cellular Toxicology, North Carolina State University
- 2002 MEM, Nicholas School of the Environment and Earth Sciences, Duke University
- 1998 BS, Atomic Science, National Tsing-Hua Unversity
Experience
- 2024.02- Director, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019- Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019- Associate Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2019- Associate Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2019.01-2019.12 Chief, International Research, Office of Global Engagement, Taipei Medical University
- 2018-2019 Assistant Professor, Ph.D. Program in Biotechnology Resaerch and Development, Taipei Medical University
- 2018-2019 Assistant Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery Taipei Medical University
- 2013-2019 Assistant, Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2010-2011 PharmaEssentia Corp. Senior Scientist
- 2007-2010 University of Pennsylvania, Postdoctoral fellow
Research Interests
- Cancer Biology
- Signal Transduction
- Molecular Toxicology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(3/3)
HuangFu, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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運用互動教學模式以增進EMI教學之學習成效-以藥物設計與開發為例
HuangFu, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › d - Ministry of Education
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研發新穎性 HGK 抑制劑在胰臟癌中之抗 癌效用與機轉探討
HuangFu, W.-C. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(2/3)
HuangFu, W.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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新穎性DYRK1B抑制劑用於胰臟癌之藥理機轉探討與藥物研發(2/3)
HuangFu, W.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Epigenetic Modifications as Novel Therapeutic Strategies of Cancer Chemoprevention by Phytochemicals
Hsieh, H. H., Kuo, M. Z., Chen, I. A., Lin, C. J., Hsu, V., HuangFu, W. C. & Wu, T. Y., 2025, (Accepted/In press) In: Pharmaceutical Research. 42, 1, p. 69-78 10 p., 111502.Research output: Contribution to journal › Article › peer-review
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An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., Jun 2024, In: Protein Science. 33, 6, e5007.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells
Chan, T. S., Cheng, L. H., Hsu, C. C., Yang, P. M., Liao, T. Y., Hsieh, H. Y., Lin, P. C., HuangFu, W. C., Chuu, C. P. & Tsai, K. K., 2024, (Accepted/In press) In: Molecular Oncology. 18, 3, p. 562-579 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
Tu, H. J., Chao, M. W., Lee, C. C., Peng, C. S., Wu, Y. W., Lin, T. E., Chang, Y. W., Yen, S. C., Hsu, K. C., Pan, S. L. & HuangFu, W. C., 2024, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 39, 1, 2418470.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitors using an artificial intelligence model and their effects on tau and tubulin dynamics
Chen, J. H., Tu, H. J., Lin, T. E., Peng, Z. X., Wu, Y. W., Yen, S. C., Sung, T. Y., Hsieh, J. H., Lee, H. Y., Pan, S. L., HuangFu, W. C. & Hsu, K. C., Dec 2024, In: Biomedicine and Pharmacotherapy. 181, 117688.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Pan, S.-L. (Contributor), Hsu, K.-C. (Creator), Lin, T. E. (Creator), Lin, C.-F. (Creator), Huang, H.-L. (Contributor) & Huangfu, W.-C. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1
Dataset
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Additional file 2 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody
Huang, H.-L. (Contributor), HuangFu, W.-C. (Creator), Cheng, Y.-W. (Creator), Cheng, C.-C. (Creator), Chang, F.-L. (Creator), Sung, T.-Y. (Creator), Pan, S.-L. (Creator), Lee, Y.-C. (Contributor), Wei, P.-L. (Contributor) & Huang, C.-C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.14228281.v1, https://doi.org/10.6084%2Fm9.figshare.14228281.v1
Dataset
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Additional file 1 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody
Cheng, Y.-W. (Creator), Cheng, C.-C. (Creator), HuangFu, W.-C. (Creator), Pan, S.-L. (Creator), Sung, T.-Y. (Creator), Chang, F.-L. (Creator), Huang, H.-L. (Contributor), Huang, C.-C. (Contributor), Wei, P.-L. (Contributor) & Lee, Y.-C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.14228278.v1, https://doi.org/10.6084%2Fm9.figshare.14228278.v1
Dataset
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
Dataset
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EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody
Sung, T.-Y. (Creator), Huang, H.-L. (Contributor), Cheng, C.-C. (Creator), Chang, F.-L. (Creator), Wei, P.-L. (Contributor), Cheng, Y.-W. (Creator), Huang, C.-C. (Contributor), Lee, Y.-C. (Contributor), HuangFu, W.-C. (Creator) & Pan, S.-L. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5341486.v1, https://springernature.figshare.com/collections/EGFL6_promotes_colorectal_cancer_cell_growth_and_mobility_and_the_anti_cancer_property_of_anti-EGFL6_antibody/5341486/1
Dataset