Personal profile
Education
- 2012 Ph.D., Institute of Basic Medical Sciences, National Cheng Kung University.
- 2007 M.S., Department of Physiology, National Cheng Kung University.
- 2004 B.S., Department of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology
Experience
- 2025- Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2022-2025 Associate Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2019-2022 Assistant Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2018-2019 Research Assistant, Neuroscience Research Center, Taipei Medical University
- 2017-2019 Research Assistant, The Ph.D.Program for Neural Regenerative Medicine, Taipei Medical University
- 2016-2018 Research Assistant, Center for Neurotrauma and Neuroregeneration, Taipei Medical University
- 2012-2015 Post-Doctor, Center of Infectious Disease and Signal Research, Nationa Cheng Kung University
Awards
- 2014 Excellent Research Award of Post-Doctor by Ministry of Science and Technology.
- 2012 Outstanding Research Award of Medical College in National Cheng Kung University
Research Interests
- Tumor Biology
- Cancer mouse models
Related Link
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Targeting Glioblastoma Resilience: Role of Progesterone in Enhancing Chemotherapeutic and Immunotherapeutic Responses through Modulating Protein Sialylation
Hsu, T.-I. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Role of Mif in Impairing Mtor-Mediated Metabolic Reprogramming for Nk Dysfunction( I )
Hsu, T.-I. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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替莫唑胺結合美金剛胺之衍生藥物對於膠質母細胞瘤與星狀細胞瘤的治療效果與機制探討
Hsu, T.-I. (PI)
7/1/25 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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利用介孔二氧化矽奈米顆粒對抗由SPP1介導的免疫抑制並增強NK細胞成熟中的mTOR信號以對抗膠質母細胞瘤
Hsu, T.-I. (PI)
3/1/25 → 2/28/26
Project: C - Project of Alliance › o - Chi Mei Medical Center
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Evaluating the Potential Efficacy of Gamma-Delta (γδ) T Cell Therapy on Hepatocellular Carcinoma
Hsu, T.-I. (PI) & Shen, C.-J. (CoPI)
3/1/25 → 2/28/26
Project: D - Other Project
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Dual suppression of stemness and redox adaptation in glioblastoma through filaggrin upregulation by an abiraterone-based HDAC inhibitor
Tran, H. Y., Sharma, R., Lin, H.-Y., Yeh, T.-Y., Shen, C.-J., Hsu, T.-I. & Liou, J.-P., Dec 2026, In: Journal of Biomedical Science. 33, 1, 38.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting the COX-2/PGE2 axis to enhance NK and T cell immunotherapy in brain tumors
Shen, C.-J., Florentino-Krasnov, J., Liao, Y.-C., Tang, H.-W., Nainggolan, B. W. M., Chiang, Y.-H. & Hsu, T.-I., May 2026, In: Cancer Immunology, Immunotherapy. 75, 5, 141.Research output: Contribution to journal › Review article › peer-review
Open Access -
Unmodified γδ T cells exhibit potent antitumor activity in hepatocellular carcinoma and are enhanced by PD-L1 blockade
Zhang, B.-X. B., Lin, H.-Y., Tran, H. Y., Wu, C.-C., Chen, K.-Y., Hsu, T.-I. & Shen, C.-J., Mar 2026, In: Immunobiology. 231, 2, 153163.Research output: Contribution to journal › Article › peer-review
Open Access -
A Dual CYP17A1/HDAC6 Inhibitor for Targeted Prostate Cancer Therapy
Tran, H. Y., Lin, C. L., Lin, H. Y., Shen, C. J., Sharma, R., Liou, J. P. & Hsu, T. I., Oct 2025, In: FASEB Journal. 39, 20, e71152.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Citation (Scopus) -
Contribution of Prostaglandin E2-Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative
Shen, C. J., Chen, H. C., Lin, C. L., Thakur, A., Onuku, R., Chen, I. C., Li, H. Y., Chang, K. Y., Chuang, J. Y., Yang, W. B., Lin, H. Y., Shen, Y. R., Liou, J. P., Chang, W. C. & Hsu, T. I., Oct 13 2025, In: Advanced Science. 12, 38, e06336.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Citations (Scopus)
Datasets
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MOESM4 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Lo, W.-L. (Creator), Chu, J.-M. (Contributor), Yang, K.-Y. (Creator), Liu, M.-S. (Creator), Liu, J.-J. (Creator), Chen, P.-Y. (Contributor), Chung, P.-H. (Contributor), Chuang, J.-Y. (Creator), Chien, C.-H. (Contributor), Chang, K.-Y. (Contributor), Yang, W.-B. (Creator), Huang, C.-Y. (Contributor), Yang, S.-T. (Creator), Chen, S.-H. (Contributor), Chou, S.-W. (Creator) & Hsu, T.-I. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006862.v1, https://doi.org/10.6084%2Fm9.figshare.10006862.v1
Dataset
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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y.-T. (Creator), Lo, W.-L. (Creator), Chen, P.-Y. (Creator), Ko, C.-Y. (Creator), Chuang, J.-Y. (Creator), Kao, T.-J. (Creator), Yang, W.-B. (Creator), Chang, K.-Y. (Creator), Hung, C.-Y. (Creator), Kikkawa, U. (Creator), Chang, W.-C. (Creator) & Hsu, T.-I. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1
Dataset
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Additional file 1: of CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
Chen, Y.-L. (Contributor), Chuang, J.-Y. (Creator), Wang, S.-M. (Creator), Kao, T.-J. (Contributor), Lin, H.-Y. (Creator), Ko, C.-Y. (Contributor) & Hsu, T.-I. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8866895.v1, https://doi.org/10.6084%2Fm9.figshare.8866895.v1
Dataset
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MOESM3 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J.-J. (Creator), Hsu, T.-I. (Contributor), Chou, S.-W. (Creator), Chuang, J.-Y. (Creator), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Yang, S.-T. (Creator), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Chien, C.-H. (Contributor), Chung, P.-H. (Contributor), Lo, W.-L. (Creator), Liu, M.-S. (Creator) & Chang, K.-Y. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006856.v1, https://doi.org/10.6084%2Fm9.figshare.10006856.v1
Dataset
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MOESM8 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chung, P.-H. (Contributor), Chen, S.-H. (Contributor), Hsu, T.-I. (Contributor), Liu, M.-S. (Creator), Lo, W.-L. (Creator), Chu, J.-M. (Contributor), Yang, K.-Y. (Creator), Yang, S.-T. (Creator), Liu, J.-J. (Creator), Chuang, J.-Y. (Creator), Yang, W.-B. (Creator), Huang, C.-Y. (Contributor), Chien, C.-H. (Contributor), Chang, K.-Y. (Contributor), Chen, P.-Y. (Contributor) & Chou, S.-W. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006883.v1, https://doi.org/10.6084%2Fm9.figshare.10006883.v1
Dataset