Projects per year
Personal profile
Education
- 2012 Ph.D., Institute of Basic Medical Sciences, National Cheng Kung University.
- 2007 M.S., Department of Physiology, National Cheng Kung University.
- 2004 B.S., Department of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology
Experience
- 2025- Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2022-2025 Associate Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2019-2022 Assistant Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2018-2019 Research Assistant, Neuroscience Research Center, Taipei Medical University
- 2017-2019 Research Assistant, The Ph.D.Program for Neural Regenerative Medicine, Taipei Medical University
- 2016-2018 Research Assistant, Center for Neurotrauma and Neuroregeneration, Taipei Medical University
- 2012-2015 Post-Doctor, Center of Infectious Disease and Signal Research, Nationa Cheng Kung University
Awards
- 2014 Excellent Research Award of Post-Doctor by Ministry of Science and Technology.
- 2012 Outstanding Research Award of Medical College in National Cheng Kung University
Research Interests
- Tumor Biology
- Cancer mouse models
Related Link
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting Glioblastoma Resilience: Role of Progesterone in Enhancing Chemotherapeutic and Immunotherapeutic Responses through Modulating Protein Sialylation
Hsu, T.-I. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Role of Mif in Impairing Mtor-Mediated Metabolic Reprogramming for Nk Dysfunction( I )
Hsu, T.-I. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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替莫唑胺結合美金剛胺之衍生藥物對於膠質母細胞瘤與星狀細胞瘤的治療效果與機制探討
Hsu, T.-I. (PI)
7/1/25 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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利用介孔二氧化矽奈米顆粒對抗由SPP1介導的免疫抑制並增強NK細胞成熟中的mTOR信號以對抗膠質母細胞瘤
Hsu, T.-I. (PI)
3/1/25 → 2/28/26
Project: C - Project of Alliance › o - Chi Mei Medical Center
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Evaluating the Potential Efficacy of Gamma-Delta (γδ) T Cell Therapy on Hepatocellular Carcinoma
Hsu, T.-I. (PI) & Shen, C.-J. (CoPI)
3/1/25 → 2/28/26
Project: D - Other Project
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A Dual CYP17A1/HDAC6 Inhibitor for Targeted Prostate Cancer Therapy
Tran, H. Y., Lin, C.-L., Lin, H.-Y., Shen, C.-J., Sharma, R., Liou, J.-P. & Hsu, T.-I., Oct 31 2025, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 39, 20, p. e71152Research output: Contribution to journal › Article › peer-review
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Contribution of Prostaglandin E2-Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood-Brain Barrier Crossing Celecoxib Derivative
Shen, C.-J., Chen, H.-C., Lin, C.-L., Thakur, A., Onuku, R., Chen, I.-C., Li, H.-Y., Chang, K.-Y., Chuang, J.-Y., Yang, W.-B., Lin, H.-Y., Shen, Y.-R., Liou, J.-P., Chang, W.-C. & Hsu, T.-I., Jul 14 2025, (E-pub ahead of print) In: Advanced Science. p. e06336Research output: Contribution to journal › Article › peer-review
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Potential role of solid lipid curcumin particle (SLCP) as estrogen replacement therapy in mitigating TDP-43-related neuropathy in the mouse model of ALS disease
Majumder, P., Hsu, T. I., Hu, C. J., Huang, J. K., Lee, Y. C., Hsieh, Y. C., Ahsan, A. & Huang, C. C., Jan 2025, In: Experimental Neurology. 383, 114999.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Repurposing Linezolid in Conjunction with Histone Deacetylase Inhibitor Access in the Realm of Glioblastoma Therapies
Chen, I. C., Lin, H. Y., Liu, Z. Y., Cheng, W. J., Yeh, T. Y., Yang, W. B., Tran, H. Y., Lai, M. J., Wang, C. H., Kao, T. Y., Hung, C. Y., Huang, Y. L., Liou, K. C., Hsieh, C. M., Hsu, T. I. & Liou, J. P., 2025, In: Journal of Medicinal Chemistry. 68, 3, p. 2779-2803 25 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress
Sharma, R., Chiang, Y. H., Chen, H. C., Lin, H. Y., Yang, W. B., Nepali, K., Lai, M. J., Chen, K. Y., Liou, J. P. & Hsu, T. I., Apr 1 2024, In: Cancer Letters. 586, 216666.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus)
Datasets
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MOESM2 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chen, P.-Y. (Contributor), Yang, W.-B. (Creator), Chou, S.-W. (Creator), Yang, S.-T. (Creator), Chung, P.-H. (Contributor), Chang, K.-Y. (Contributor), Liu, M.-S. (Creator), Chen, S.-H. (Contributor), Chien, C.-H. (Contributor), Hsu, T.-I. (Contributor), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Liu, J.-J. (Creator), Chuang, J.-Y. (Creator) & Lo, W.-L. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006850.v1, https://doi.org/10.6084%2Fm9.figshare.10006850.v1
Dataset
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MOESM5 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J.-J. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Chu, J.-M. (Contributor), Chien, C.-H. (Contributor), Yang, W.-B. (Creator), Lo, W.-L. (Creator), Hsu, T.-I. (Contributor), Yang, K.-Y. (Creator), Chung, P.-H. (Contributor), Chou, S.-W. (Creator), Chang, K.-Y. (Contributor), Yang, S.-T. (Creator), Chuang, J.-Y. (Creator), Huang, C.-Y. (Contributor) & Liu, M.-S. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006868.v1, https://doi.org/10.6084%2Fm9.figshare.10006868.v1
Dataset
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MOESM3 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J.-J. (Creator), Hsu, T.-I. (Contributor), Chou, S.-W. (Creator), Chuang, J.-Y. (Creator), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Yang, S.-T. (Creator), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Chien, C.-H. (Contributor), Chung, P.-H. (Contributor), Lo, W.-L. (Creator), Liu, M.-S. (Creator) & Chang, K.-Y. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006856.v1, https://doi.org/10.6084%2Fm9.figshare.10006856.v1
Dataset
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Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chien, C.-H. (Contributor), Chuang, J.-Y. (Creator), Yang, S.-T. (Creator), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor), Hsu, T.-I. (Contributor), Huang, C.-Y. (Contributor), Lo, W.-L. (Creator), Yang, K.-Y. (Creator), Liu, M.-S. (Creator), Chu, J.-M. (Contributor), Chung, P.-H. (Contributor), Liu, J.-J. (Creator), Chou, S.-W. (Creator), Chen, S.-H. (Contributor) & Chang, K.-Y. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4705370.v1, https://doi.org/10.6084%2Fm9.figshare.c.4705370.v1
Dataset
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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y.-T. (Creator), Lo, W.-L. (Creator), Chen, P.-Y. (Creator), Ko, C.-Y. (Creator), Chuang, J.-Y. (Creator), Kao, T.-J. (Creator), Yang, W.-B. (Creator), Chang, K.-Y. (Creator), Hung, C.-Y. (Creator), Kikkawa, U. (Creator), Chang, W.-C. (Creator) & Hsu, T.-I. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1
Dataset