Projects per year
Personal profile
Education
- 2012 Ph.D., Institute of Basic Medical Sciences, National Cheng Kung University.
- 2007 M.S., Department of Physiology, National Cheng Kung University.
- 2004 B.S., Department of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology
Experience
- 2022- Associate Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2019-2022 Assistant Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2018-2019 Research Assistant, Neuroscience Research Center, Taipei Medical University
- 2017-2019 Research Assistant, The Ph.D.Program for Neural Regenerative Medicine, Taipei Medical University
- 2016-2018 Research Assistant, Center for Neurotrauma and Neuroregeneration, Taipei Medical University
- 2012-2015 Post-Doctor, Center of Infectious Disease and Signal Research, Nationa Cheng Kung University
Awards
- 2014 Excellent Research Award of Post-Doctor by Ministry of Science and Technology.
- 2012 Outstanding Research Award of Medical College in National Cheng Kung University
Research Interests
- Tumor Biology
- Cancer mouse models
Related Link
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 16 Finished
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透過調整腫瘤細胞中的類固醇合成至别孕烷醇酮和重新編程脂肪酸代謝來促進自然殺手細胞治療膠質母細胞瘤
Hsu, T.-I. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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探討前列腺素E2調節之神經細胞活化在神經膠質母細胞瘤產生帝盟多抗性中的角色
Hsu, T.-I. (PI)
3/1/23 → 2/29/24
Project: C - Project of Alliance › o - Chi Mei Medical Center
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The Role of Fatty Acid Metabolic Reprogramming Associated with Mitochondrial Dna Mutations in the Drug Resistance of Glioblastoma
Hsu, T.-I. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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探討神經類固醇用於診斷及治療神經退化性疾病之潛力
Hsu, T.-I. (PI)
3/1/22 → 2/28/23
Project: C - Project of Alliance › o - Chi Mei Medical Center
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闡明化療對前列腺素E2介導的膠質母細胞瘤和神經元之間交互作用的影響
Hsu, T.-I. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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Potential role of solid lipid curcumin particle (SLCP) as estrogen replacement therapy in mitigating TDP-43-related neuropathy in the mouse model of ALS disease
Majumder, P., Hsu, T. I., Hu, C. J., Huang, J. K., Lee, Y. C., Hsieh, Y. C., Ahsan, A. & Huang, C. C., Jan 2025, In: Experimental Neurology. 383, 114999.Research output: Contribution to journal › Article › peer-review
Open Access -
Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress
Sharma, R., Chiang, Y. H., Chen, H. C., Lin, H. Y., Yang, W. B., Nepali, K., Lai, M. J., Chen, K. Y., Liou, J. P. & Hsu, T. I., Apr 1 2024, In: Cancer Letters. 586, 216666.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Exploring neuron-specific steroid synthesis and DHEAS therapy in Alzheimer's disease
Lin, H. Y., Feng, Y. H., Kao, T. J., Chen, H. C., Chen, G. Y., Ko, C. Y. & Hsu, T. I., Oct 2024, In: Journal of Steroid Biochemistry and Molecular Biology. 243, 106585.Research output: Contribution to journal › Article › peer-review
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First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity In Vitro and In Vivo
Sharma, S., Wang, S. A., Yang, W. B., Lin, H. Y., Lai, M. J., Chen, H. C., Kao, T. Y., Hsu, F. L., Nepali, K., Hsu, T. I. & Liou, J. P., Feb 22 2024, In: Journal of Medicinal Chemistry. 67, 4, p. 2963-2985 23 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma
Li, H. Y., Feng, Y. H., Lin, C. L. & Hsu, T. I., Mar 2024, In: Mitochondrion. 75, 101836.Research output: Contribution to journal › Review article › peer-review
3 Citations (Scopus)
Datasets
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Additional file 1: of Suberoylanilide hydroxamic acid represses glioma stem-like cells
Chang, K.-Y. (Creator), Wang, J.-Y. (Creator), Chuang, J.-Y. (Creator), Ko, C.-Y. (Contributor), Hsu, T.-I. (Contributor), Chang, W.-C. (Creator), Yeh, S.-H. (Contributor), Liou, J.-P. (Creator), Liu, J.-J. (Contributor) & Hsu, C.-C. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3596465_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465_d1.v1
Dataset
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MOESM2 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chen, P.-Y. (Contributor), Yang, W.-B. (Creator), Chou, S.-W. (Creator), Yang, S.-T. (Creator), Chung, P.-H. (Contributor), Chang, K.-Y. (Contributor), Liu, M.-S. (Creator), Chen, S.-H. (Contributor), Chien, C.-H. (Contributor), Hsu, T.-I. (Contributor), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Liu, J.-J. (Creator), Chuang, J.-Y. (Creator) & Lo, W.-L. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006850.v1, https://doi.org/10.6084%2Fm9.figshare.10006850.v1
Dataset
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Additional file 1 of Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y.-T. (Creator), Lo, W.-L. (Creator), Chen, P.-Y. (Creator), Ko, C.-Y. (Creator), Chuang, J.-Y. (Creator), Kao, T.-J. (Creator), Yang, W.-B. (Creator), Chang, K.-Y. (Creator), Hung, C.-Y. (Creator), Kikkawa, U. (Creator), Chang, W.-C. (Creator) & Hsu, T.-I. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.19425032.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/19425032/1
Dataset
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MOESM6 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chuang, J.-Y. (Creator), Chen, S.-H. (Contributor), Yang, K.-Y. (Creator), Chien, C.-H. (Contributor), Liu, J.-J. (Creator), Hsu, T.-I. (Contributor), Chang, K.-Y. (Contributor), Yang, S.-T. (Creator), Chu, J.-M. (Contributor), Chou, S.-W. (Creator), Lo, W.-L. (Creator), Liu, M.-S. (Creator), Huang, C.-Y. (Contributor), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor) & Chung, P.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006874.v1, https://doi.org/10.6084%2Fm9.figshare.10006874.v1
Dataset
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MOESM7 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chou, S.-W. (Creator), Chen, P.-Y. (Contributor), Chu, J.-M. (Contributor), Chien, C.-H. (Contributor), Liu, J.-J. (Creator), Liu, M.-S. (Creator), Chuang, J.-Y. (Creator), Chung, P.-H. (Contributor), Hsu, T.-I. (Contributor), Chen, S.-H. (Contributor), Yang, S.-T. (Creator), Lo, W.-L. (Creator), Huang, C.-Y. (Contributor), Chang, K.-Y. (Contributor), Yang, K.-Y. (Creator) & Yang, W.-B. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006880.v1, https://doi.org/10.6084%2Fm9.figshare.10006880.v1
Dataset