Projects per year
Personal profile
Education
- 1985-1989 Ph.D., Graduate Institute of Medical Sciences, National Defense Medical Center
- 1976-1983 M.D., School of Medicine, National Defense Medical Center
Experience
- 2024.03- Director of Cancer Center, Taipei Medical University Shuang Ho Hospital
- 2020.11- Professor, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University
- 2018.11- Deputy Director, Taipei Cancer Center, Taipei Medical University
- Director, Division of Oncology, Department of Internal Medicine, College of Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2015.10-2019.07.31 Deputy Director, Department of Human Research, Taipei Medical University
- 2015.02- Chief, Department of Medical Affairs, Shuang Ho Hospital, Taipei Medical University
- 2014.02-2016.07 Director, Joint Clinical Research Center, Taipei Medical University
- 2010.10- Chief and Professor, Division of Hematology/Oncology, Shuang-Ho Hospital, Taipei Medical University,
- 2010.10-2015.01 Chief and Professor, Division of Internal Medicine, Shuang-Ho Hospital, Taipei Medical University, Taipei, Taiwan
- 2010.09- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2010.05- Director, Division of Oncology, Tri-Service General Hospital
- 1997.08-2010.09 Chief and Professor, Division of Hematology/Oncology, Tri-Service General Hospital, National Defense Medical Center,
- 1992.08-2010.09 Attending Physician, Division of Hematology/Oncology, Tri-Service General Hospital
- 1989.07-1997.07 Associate Professor, National Defense Medical Center
- 1987-1789 Research Fellow, Department of Immunology and Biochemistry Research, Roswell Park Memorial Institute,
- 1983.08-1992.07 Resident, Chief Resident, Fellow, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center
- 1983.08-1989.06 Teaching Assistant, National Defense Medical Center
Awards
- 2019 Distinguished Clinical Trial Leader Award, Taipei Medical University
- 2008 The best 100 physicians of Taiwan
- 2005 Teacher of the year, National Defense University
- 2001 Remarkable physician of Tri-Service General Hospital
- 2000 Teacher of the year, National Defense Medical Center. September
- 1998 Decent Man, Tri-Service General Hospital
- 1997 International Who's Who of Contemporary Achievement, Hall of Fame, awarded by the American Biographical Institute
- 1996 Men of Achievement, 17th edition, published by The International Biographical Center, Cambridge, England
- 1994 Outstanding Military Physician honored by the Ministry of Defense, Taiwan, R. O. C.
- 1994-1995 Scholarship of Biomedical Science for physician awarded by Academia Sinica, Taiwan, R. O. C.
- 1993 Distinguished Youth of Taipei City
- 1992 Remarkable physician of Tri-Service General Hospital
- 1989 First class Academic Medal, awarded by Ministry of Defense, R. O. C.
- 1983 Second class Academic Medal, awarded by Ministry of Defense, R. O. C.
Research Interests
- Dr. Chao’s current researchinterests focus on clinical trials and translational studies. The clinical trials he involves are about the development of new drugs or strategies in treating cancers and hematological disorders. In translational studies, his major effort is on the development of a novel biochemical marker, i.e. tartrate-resistant acid phosphatase 5b, in the diagnosis and monitoring of metastatic bone disease of breast cancer. He also intends to define the role and search the potential usefulness of tartrate-resistant acid phosphatase 5a in macrophage-related disorders.
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Collaborations and top research areas from the last five years
Projects
- 9 Finished
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探討新型鐵凋亡生物標誌在MYC基因重排雙突變淋巴癌中的治療價值(2/3)
Chao, T.-Y. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Investigation of the Diagnostic and Therapeutic Value to Novel Ferroptotic Biomarkers in Double Hit Lymphoma( I )
Chao, T.-Y. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Role of Btk/Her2 Signaling as a Therapeutic Target for Restoration of T Cell Function and Reversal of Trastuzumab Resistance in Her2+ Breast Cancer
Chao, T.-Y. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(2/3)
Chao, T.-Y. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色:調控T細胞的效應及逆轉賀癌平抗藥性的分子機制
Chao, T.-Y. (PI)
1/1/20 → 12/31/20
Project: A - Government Institution › a - National Health Research Institutes
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Neurocutaneous Melanosis with Meningeal Melanocytosis: A Rare Case of Intracranial Hypertension and Cutaneous Manifestations
Chen, H. C., Hsu, T. I., Chao, T. Y. & Yang, S. T., Jan 2024, In: Life. 14, 1, 139.Research output: Contribution to journal › Article › peer-review
Open Access -
Whole-Brain Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Untreated Brain Metastases from Breast Cancer: A Randomized Clinical Trial
Chen, T. W. W., Dai, M. S., Tseng, L. M., Chen, S. C., Chao, T. Y., Chao, T. C., Chang, Y. C., Chiu, C. F., Liu, C. T., Lin, C. H., Liu, C. Y., Chen, Y. F., Chang, D. Y., Yu, J. C., Rau, K. M., Hsieh, Y. Y., Shen, S. C., Huang, S. M., Cheng, A. L. & Lu, Y. S., Mar 21 2024, In: JAMA oncology. 10, 3, p. 325-334 10 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Oral paclitaxel and encequidar in patients with breast cancer: a pharmacokinetic, safety, and antitumor activity study
Dai, M. S., Chao, T. C., Chiu, C. F., Lu, Y. S., Shiah, H. S., Jackson, C. G. C. A., Hung, N., Zhi, J., Cutler, D. L., Kwan, R., Kramer, D., Chan, W. K., Qin, A., Tseng, K. C., Hung, C. T. & Chao, T. Y., 2023, In: Therapeutic Advances in Medical Oncology. 15Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Personalized cancer avatars for patients with thymic malignancies: A pilot study with circulating tumor cell-derived organoids
Wu, Y.-H., Chao, H.-S., Chiang, C.-L., Luo, Y.-H., Chiu, C.-H., Yen, S.-H., Liu, C.-Y., Chiou, J.-F., Burnouf, T., Chen, Y.-J., Wang, P.-Y., Chao, T.-Y., Hsu, S.-M. & Lu, L.-S., Sept 2023, In: Thoracic Cancer. 14, 25, p. 2591-2600 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Synergistic disruption of BTK and BCL-2 causes apoptosis while inducing ferroptosis in double-hit lymphoma
Setiawan, S. A., Liu, W. Z., Weng, P. W., Lee, C. H., Yadav, V. K., Hardianti, M. S., Yeh, C. T. & Chao, T. Y., Mar 15 2023, In: European Journal of Pharmacology. 943, 175526.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus)
Datasets
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Additional file 1: of Monospecific antibody targeting of CDH11 inhibits epithelial-to-mesenchymal transition and represses cancer stem cell-like phenotype by up-regulating miR-335 in metastatic breast cancer, in vitro and in vivo
Chen, J.-H. (Creator), Huang, W.-C. (Contributor), Bamodu, O. A. (Contributor), Chang, P.M.-H. (Creator), Chao, T.-Y. (Contributor) & Huang, T.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8341985.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Monospecific_antibody_targeting_of_CDH11_inhibits_epithelial-to-mesenchymal_transition_and_represses_cancer_stem_cell-like_phenotype_by_up-regulating_miR-335_in_metastatic_breast_cancer_in_vitro_and_in_vivo/8341985/1
Dataset
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Additional file 2: Figure S1. of Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
Yeh, C.-T. (Contributor), Huang, W.-C. (Contributor), Wu, A. (Creator), Bamodu, O. A. (Contributor), Lee, W.-H. (Contributor), Wang, L. S. (Creator), Chao, T.-Y. (Contributor) & Hsiao, M. (Creator), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3621719_d3.v1, https://doi.org/10.6084%2Fm9.figshare.c.3621719_d3.v1
Dataset
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Additional file 1: of Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience
Lai, C.-C. (Contributor), Fan, H.-C. (Contributor), Chu, D.-M. (Contributor), Wang, C.-C. (Contributor), Chen, S.-J. (Contributor), Chao, T.-Y. (Contributor) & Lin, C.-M. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3630170_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3630170_d1.v1
Dataset
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Additional file 1: of A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment
Chung, T.-R. (Contributor), Ch'Ang, H.-J. (Contributor), Kao, W.-Y. (Contributor), Wu, Y.-C. (Creator), Chang, J.-Y. (Contributor), Yu, W.-L. (Contributor), Liu, K.-J. (Contributor), Chao, T.-Y. (Contributor), Whang-Peng, J. (Creator) & Cheng, A.-L. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3612833_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3612833_d2.v1
Dataset
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Additional file 2: of A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment
Whang-Peng, J. (Creator), Wu, Y.-C. (Creator), Chao, T.-Y. (Contributor), Kao, W.-Y. (Contributor), Liu, K.-J. (Contributor), Cheng, A.-L. (Contributor), Ch'Ang, H.-J. (Contributor), Chung, T.-R. (Contributor), Chang, J.-Y. (Contributor) & Yu, W.-L. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3612833_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3612833_d1.v1
Dataset