Projects per year
Personal profile
Education
- 2012 Ph.D., Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 1981-1985 M.D., School of Medicine, University of Santo Tomas
- 1978-1981 B.S., Department of Science Accelerated, University of Santo Tomas
Experience
- 2022.02- Professor, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University
- Director, Division of Metabolism, Department of Internal Medicine, Taipei Municipal Wanfang Hospital
- 2019.08- Director, Department of Metabolism, School of Medicine, College of Medicine, Taipei Medical University
- 2012- Examiner OSCE Taiwan Institute of Medical Education
- 1997- Consultant & Head, Diabetic Education Center, Wan Fang Hospital
- 2021.02-2022.01 Associate Professor, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University
- 2014.02-2021.01 Associate Professor, School of Medicine, College of Medicine, Taipei Medical University
- 2013-2018 Board Committee, Taipei Military Services
- 2003.08-2009.07 Instructor, School of Medicine, Taipei Medical University
- 2012-2016 Executive board The Endocrine Society of Republic of China
- 2011-2017 Representative of Society of Internal Medicine
- 2009.08-2014.01 Assistant Professor, School of Medicine, Taipei Medical University
- 2009-2011 Board Committee National Conspiracy Agency, Ministry of the Interior, Military Services
- 2005-2017 Representative of Taiwan Association of Diabetes Education
- 1996.08-1999.09 Attending Physician, Central Clinic Hospital
- 1996.08-2007.12 Physician, Taipei Veterans General Hospital
- 1996.07-1997.06 Clinical Instructor, National Defense Medical Center
- 1994.08-1996.07 Fellowship training Endocrinology and Metabolism, Taipei Veterans General Hospital
- 1996-1997 Clinical Instructor, School of Medicine, National Defense Medical Center
- 1996-2007 Visiting consultant, Taipei Veterans General Hospital 9
- 1997-2000 Consultant, Central Health Insurance Bureau of Taipei Joint Outpatient Clinic
- 1996-1999 Executive board, Taiwan Association of Diabetes Education
- 1989.07-1994.06 Chief Resident Physician, Department of Internal Medicine, Central Clinic & Hospital
Awards
- 2015 The Diabetes Association and Endocrine Society of Republic of China, Outstanding Paper Award
- 2014 Taipei Medical Center Diabetes Shared Care Medical Quality-2nd prize
- 2013 Taipei Medical Center Diabetes Shared Care Medical Quality 2nd Prize
- 2012 Taipei Medical Center Diabetes Shared Care Medical Quality 1st Prize
- 2012 Taipei Medical University School of Medicine, Postgraduate Thesis Merit Award
- 2012 Asian-Pacific Bayer Chinese Diabetes Forum 2012 Outstanding Poster Award
- 2012 The Diabetes Association and Endocrine Society of Republic of China, Outstanding Paper Award
Research Interests
- Clinical and basic research in Diabetes
- Clinical and basic research on Endocrine diseases
- Clinical research on new drugs development
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Collaborations and top research areas from the last five years
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Cardiac-Targeting Exosomal Microrna-452 in Myocarditis: Addressing Mitochondrial Dysfunction and Metabolic–Epigenetic Crosstalk( I )
Lee, T.-I. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Ketone Body Beta-Hydroxybutyrate Mitigates Diabetic Cardiomyopathy via Cross-Talk with Fgf-21 Signaling
Lee, T.-I. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Inhibition of Nlrp3-Inflammasome- a Novel Therapeutic Strategy for Diabetic Cardiomyopathy
Lee, T.-I. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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Liraglutide與Empagliflozin在糖尿病心肌病變不同地調控心臟代謝:抗糖尿病藥物的獨特心臟保護作用
Lee, T.-I. (PI)
3/1/20 → 7/31/21
Project: C - Project of Alliance › q - Cathay General Hospital
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Molecular Insights into Ketogenic Diet on Cardiac Metabolic Disorders in Diabetic Cardiomyopathy
Lee, T.-I. (PI)
8/1/19 → 7/31/20
Project: A - Government Institution › b - National Science and Technology Council
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Calcitriol deficiency reduces myocardial ATP production with disturbed mitochondrial dynamics and increased uncoupling protein 2 expression
Lee, T. W., Lee, T. I., Higa, S., Kao, Y. H. & Chen, Y. J., Sept 5 2025, In: European Journal of Pharmacology. 1002, 177858.Research output: Contribution to journal › Article › peer-review
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Metabolic benefits of therapeutic exercise in older adults with type 2 diabetes mellitus and multimorbidity: a retrospective cohort study
Hung, S. E., Lee, T. I., Wang, C. Y., Liu, H. W. & Lee, T. W., Nov 2025, In: Internal Medicine Journal. 55, 11, p. 1891-1898 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Short-chain fatty acid butyrate against TMAO activating endoplasmic-reticulum stress and PERK/IRE1-axis with reducing atrial arrhythmia
Cheng, T. Y., Lee, T. W., Li, S. J., Lee, T. I., Chen, Y. C., Kao, Y. H., Higa, S., Chen, P. H. & Chen, Y. J., Jul 2025, In: Journal of Advanced Research. 73, p. 549-560 12 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis
Cheng, T. Y., Chen, Y. C., Li, S. J., Lin, F. J., Lu, Y. Y., Lee, T. I., Lee, T. W., Higa, S., Kao, Y. H. & Chen, Y. J., 2024, (Accepted/In press) In: Translational Research. 268, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Complications and comorbidities as influencing factors of health outcomes in older adults with type 2 diabetes mellitus
Yen, H. Y., Lee, S. C., Lin, C. F., Lee, T. I., Yamaguchi, Y. & Lee, P. H., Apr 2023, In: Collegian. 30, 2, p. 230-235 6 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus)
Datasets
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Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities
Lee, T.-W. (Contributor), Cheng, W.-L. (Creator), Kao, Y.-H. (Contributor), Lee, T.-I. (Contributor), Chen, Y.-J. (Contributor) & Lkhagva, B. (Contributor), Taylor & Francis, 2018
DOI: 10.6084/m9.figshare.6220217.v1, https://doi.org/10.6084%2Fm9.figshare.6220217.v1
Dataset