Projects per year
Personal profile
Education
- 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
- 2002 Master, Department of Life Science, National Tsing-Hua University
Experience
- 2025- Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2021-2025 Associate Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2020-2021 Assistant Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2020-2021 Jointly Appointed Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University
- 2017-2020 Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
- 2016-2020 Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
- 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
- 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.
Research Interests
- Drug discovery, Genomic instability, Chromatin replication
Fingerprint
Dive into the research topics where Sung-Bau Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication
Lee, S.-B. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
-
Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication
Lee, S.-B. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
-
Pharmacological investigation of HDAC8 inhibitor in perturbationof chromatin replication
Lee, S.-B. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
-
Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication and Evaluation of Its Cancer Therapeutic Potential in Combination with Checkpoint Kinase Inhibitors
Lee, S.-B. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
-
Discovery of agents disturbing genome stability during chromatin replication (2nd-4th years)
Lee, S.-B. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
-
Quinoline-5,8-dione CDC25 inhibitors: Potent anti-cancer agents in leukemia and patient-derived colorectal organoids
Narwanti, I., Yu, Z. Y., Sethy, B., Zheng, P. L., Cheng, L. H., Tsai, K. K., Lee, S. B. & Liou, J. P., Jan 5 2026, In: European Journal of Medicinal Chemistry. 301, 118215.Research output: Contribution to journal › Article › peer-review
-
Olaparib-Cediranib Hybrid as Dual PARP-VEGFR3 Inhibitor Elicits Antitumor Efficacy: Rational Design, Synthesis, Biological Evaluation and Construction of a Charge Convertible pH Responsive Nanoformulation
Rana, M., Rao, N. V. K., Yu, Z. Y., Sharma, R., Mathew, J., Chen, Y. W., Lee, S. B., Bansode, A., Hsu, T. J., Grewal, A. S., Pan, C. H., Guru, S. & Nepali, K., Oct 2025, In: Bioorganic Chemistry. 165, 109035.Research output: Contribution to journal › Article › peer-review
-
Combined HDAC8 and checkpoint kinase inhibition induces tumor-selective synthetic lethality in preclinical models
Chang, T. Y., Yan, Y., Yu, Z. Y., Rathore, M., Lee, N. Z., Tseng, H. J., Cheng, L. H., Huang, W. J., Zhang, W., Chan, E. R., Qing, Y., Kang, M. L., Wang, R., Tsai, K. K., Pink, J. J., Harte, W. E., Gerson, S. L. & Lee, S. B., Dec 2 2024, In: Journal of Clinical Investigation. 134, 23, e165448.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Design, synthesis, and biological evaluation of adenosine derivatives targeting DOT1L and HAT as anti-leukemia agents
Sethy, B., Yu, Z. Y., Narwanti, I., Upadhyay, R., Lai, M. J., Lee, S. B. & Liou, J. P., Dec 2024, In: Bioorganic Chemistry. 153, 107771.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Novel dual inhibitor targeting CDC25 and HDAC for treating triple-negative breast cancer
Sethy, B., Upadhyay, R., Narwanti, I., Yu, Z. Y., Lee, S. B. & Liou, J. P., 2024, (Accepted/In press) In: Apoptosis. 29, 11-12, p. 2047-2073 27 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus)