Projects per year
Personal profile
Education
- 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
- 2002 Master, Department of Life Science, National Tsing-Hua University
Experience
- 2021- Associate Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2020- Assistant Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2020- Jointly Appointed Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University
- 2017-2020 Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
- 2016-2020 Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
- 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
- 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.
Research Interests
- Drug discovery, Genomic instability, Chromatin replication
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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組蛋白去乙醯酶8抑制劑干擾染色質複製的藥理機轉(1/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication and Evaluation of Its Cancer Therapeutic Potential in Combination with Checkpoint Kinase Inhibitors
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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發展干擾染色質複製時期基因體穩定性之藥劑 (第二至四年)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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Targeting replication stress in cancer therapy(II)
7/1/20 → 6/30/21
Project: B - Project of TMU › i - Other (Funded by TMU)
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Discovery of Agents Disturbing Genome Stability during Chromatin Replication
8/1/19 → 7/31/20
Project: A - Government Institution › b - National Science and Technology Council
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6-Regioisomeric 5,8-quinolinediones as potent CDC25 inhibitors against colorectal cancers
Narwanti, I., Yu, Z. Y., Sethy, B., Lai, M. J., Lee, H. Y., Olena, P., Lee, S. B. & Liou, J. P., Oct 2023, In: European Journal of Medicinal Chemistry. 258, 115505.Research output: Contribution to journal › Article › peer-review
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Prudent tactics to sail the boat of PARP inhibitors as therapeutics for diverse malignancies
Rana, M., Thakur, A., Kaur, C., Pan, C. H., Lee, S. B., Liou, J. P. & Nepali, K., 2023, (Accepted/In press) In: Expert Opinion on Drug Discovery.Research output: Contribution to journal › Review article › peer-review
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Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities
Chu, J. C., Tseng, H. J., Lee, S. B., Hsu, K. C., Hsin, L. W., Liang, R. H., Lin, T. E., Gao, N. C., Chen, L. C., Lu, W. H., Wang, A. H. J. & Huang, W. J., 2023, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 38, 1, 2212326.Research output: Contribution to journal › Article › peer-review
Open Access -
Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier
Sharma, R., Chatterjee, E., Mathew, J., Sharma, S., Rao, N. V., Pan, C. H., Lee, S. B., Dhingra, A., Grewal, A. S., Liou, J. P., Guru, S. K. & Nepali, K., Oct 5 2022, In: European Journal of Medicinal Chemistry. 240, 114602.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Design, synthesis and biological evaluation of bisindole derivatives as anticancer agents against Tousled-like kinases
Lee, S. B., Chang, T. Y., Lee, N. Z., Yu, Z. Y., Liu, C. Y. & Lee, H. Y., Jan 5 2022, In: European Journal of Medicinal Chemistry. 227, 113904.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)