Projects per year
Personal profile
Education
- 2009 PhD, Graduate Institute of Life Sciences, National Defence Medical Center
- 2002 Master, Department of Life Science, National Tsing-Hua University
Experience
- 2021- Associate Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2020- Assistant Professor, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2020- Jointly Appointed Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University
- 2017-2020 Jointly Appointed Assistant Professor, Ph.D Program in Biotechnology Research and Development, Taipei Medical University.
- 2016-2020 Assistant Professor, Master Program in Clinical Pharmacogenomics & Pharmacoproteomics, Taipei Medical University.
- 2011-2016 Postdoctoral Fellow, BRIC, University of Copenhagen.
- 2009-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica.
Research Interests
- Drug discovery, Genomic instability, Chromatin replication
Fingerprint
Dive into the research topics where Sung-Bau Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
組蛋白去乙醯酶8抑制劑干擾染色質複製的藥理機轉(2/3)
Lee, S.-B. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
-
Pharmacological investigation of HDAC8 inhibitor in perturbationof chromatin replication
Lee, S.-B. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
-
Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication and Evaluation of Its Cancer Therapeutic Potential in Combination with Checkpoint Kinase Inhibitors
Lee, S.-B. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
-
Discovery of agents disturbing genome stability during chromatin replication (2nd-4th years)
Lee, S.-B. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
-
Targeting replication stress in cancer therapy(II)
Lee, S.-B. (PI)
7/1/20 → 6/30/21
Project: B - Project of TMU › i - Other (Funded by TMU)
-
Combined HDAC8 and checkpoint kinase inhibition induces tumor-selective synthetic lethality in preclinical models
Chang, T. Y., Yan, Y., Yu, Z. Y., Rathore, M., Lee, N. Z., Tseng, H. J., Cheng, L. H., Huang, W. J., Zhang, W., Chan, E. R., Qing, Y., Kang, M. L., Wang, R., Tsai, K. K., Pink, J. J., Harte, W. E., Gerson, S. L. & Lee, S. B., Dec 2 2024, In: Journal of Clinical Investigation. 134, 23, e165448.Research output: Contribution to journal › Article › peer-review
Open Access -
Design, synthesis, and biological evaluation of adenosine derivatives targeting DOT1L and HAT as anti-leukemia agents
Sethy, B., Yu, Z. Y., Narwanti, I., Upadhyay, R., Lai, M. J., Lee, S. B. & Liou, J. P., Dec 2024, In: Bioorganic Chemistry. 153, 107771.Research output: Contribution to journal › Article › peer-review
-
Novel dual inhibitor targeting CDC25 and HDAC for treating triple-negative breast cancer
Sethy, B., Upadhyay, R., Narwanti, I., Yu, Z. Y., Lee, S. B. & Liou, J. P., 2024, (Accepted/In press) In: Apoptosis. 29, 11-12, p. 2047-2073 27 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
6-Regioisomeric 5,8-quinolinediones as potent CDC25 inhibitors against colorectal cancers
Narwanti, I., Yu, Z. Y., Sethy, B., Lai, M. J., Lee, H. Y., Olena, P., Lee, S. B. & Liou, J. P., Oct 2023, In: European Journal of Medicinal Chemistry. 258, 115505.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Prudent tactics to sail the boat of PARP inhibitors as therapeutics for diverse malignancies
Rana, M., Thakur, A., Kaur, C., Pan, C. H., Lee, S. B., Liou, J. P. & Nepali, K., 2023, (Accepted/In press) In: Expert Opinion on Drug Discovery. 18, 10, p. 1169-1193 25 p.Research output: Contribution to journal › Review article › peer-review
2 Citations (Scopus)