Projects per year
Personal profile
Education
- 1998 Ph.D. (Medicinal and Natural Products Chemistry), University of Iowa
- 1987 M.S., (Pharmacy), Taipei Medical University
- 1984 B.S., (Pharmacy), Taipei Medical University
Experience
- 2013- Ph.D. Program in Clinical Drug Development of Herbal Medicine, Taipei Medical University
- 2012- Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2012-2016 Director, Department of Pharmaceutical Sciences, Taipei Medical University
- 2007-2012 Professor, School of Pharmacy, Taipei Medical University
Research Interests
- The search for bioactive substances (isolation, structure elucidation, synthesis)
- Microbial transformations of naturally occurring substances
- Synthesis of natural product-like compounds to develop new bioactive substances
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Collaborations and top research areas from the last five years
Projects
- 6 Finished
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Using Computer-Aided Drug Design and Optimization of Lead Compound to Develop Drug Candidate for Treatment of Breast Cancer
Lin, S.-J. (PI)
8/1/18 → 7/1/19
Project: A - Government Institution › b - National Science and Technology Council
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研析國際新興管制物質性質及管理政策研究
Lin, S.-J. (PI)
1/16/18 → 12/31/18
Project: A - Government Institution › c - Ministry of Health and Welfare
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國際管制藥物列管及分級制度研究
Lin, S.-J. (PI)
1/1/17 → 12/31/17
Project: A - Government Institution › c - Ministry of Health and Welfare
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結合生物轉化與分子嵌合開發天然化合物作為5alpha-reductase抑制劑
Lin, S.-J. (PI)
1/1/16 → 12/31/16
Project: C - Project of Alliance › j - National Taipei University of Technology
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Structural Modification of Terpenoids and Biological Evaluation on Immunoinflammation
Lin, S.-J. (PI)
8/1/11 → 7/31/12
Project: A - Government Institution › b - National Science and Technology Council
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Machine-Learning Based Risk Assessment for Cancer Therapy-Related Cardiac Adverse Events Among Breast Cancer Patients
Nguyen, Q. T. N., Phan, P. T., Lin, S. J., Hsu, M. H., Li, Y. C. J., Hsu, J. C. & Nguyen, P. A., Jan 25 2024, In: Studies in Health Technology and Informatics. 310, p. 1006-1010 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
A novel prediction model of the risk of pancreatic cancer among diabetes patients using multiple clinical data and machine learning
Chen, S. M., Phuc, P. T., Nguyen, P. A., Burton, W., Lin, S. J., Lin, W. C., Lu, C. Y., Hsu, M. H., Cheng, C. T. & Hsu, J. C., Oct 2023, In: Cancer Medicine. 12, 19, p. 19987-19999 13 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors
Lin, F. T., Liu, K., Wilhelms Garan, L. A., Folly-Kossi, H., Song, Y., Lin, S. J. & Lin, W. C., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 44, e2307793120.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Machine learning approaches for predicting 5-year breast cancer survival: A multicenter study
Nguyen, Q. T. N., Nguyen, P. A., Wang, C. J., Phuc, P. T., Lin, R. K., Hung, C. S., Kuo, N. H., Cheng, Y. W., Lin, S. J., Hsieh, Z. Y., Cheng, C. T., Hsu, M. H. & Hsu, J. C., 2023, (Accepted/In press) In: Cancer Science. 114, 10, p. 4063-4072 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Associations of Warfarin Use with Risks of Ischemic Cerebrovascular Events and Major Bleeding in Patients with Hyperthyroidism-Related Atrial Fibrillation
Liu, S. D., Lin, S. J., Ray, C. Y., Lin, F. T., Lin, W. C. & Wang, L. H., Nov 2022, In: Biomedicines. 10, 11, 2670.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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CCDC 722590: Experimental Crystal Structure Determination
Lin, S.-J. (Creator), Yang, L.-M. (Creator), Chou, B.-H. (Creator), Hsu, F.-L. (Creator), Chang, S.-F. (Creator), Lin, W.-K. (Creator) & Ho, Y. (Creator), Cambridge Crystallographic Data Centre, 2010
DOI: 10.5517/ccs7xc8, https://doi.org/10.5517%2Fccs7xc8
Dataset
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CCDC 722592: Experimental Crystal Structure Determination
Lin, S.-J. (Creator), Yang, L.-M. (Creator), Lin, W.-K. (Creator), Chang, S.-F. (Creator), Chou, B.-H. (Creator), Ho, Y. (Creator) & Hsu, F.-L. (Creator), Cambridge Crystallographic Data Centre, 2010
DOI: 10.5517/ccs7xfb, https://doi.org/10.5517%2Fccs7xfb
Dataset
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CCDC 898186: Experimental Crystal Structure Determination
Chang, S.-F. (Creator), Huang, T.-J. (Creator), Liu, P.-C. (Creator), Yang, L.-M. (Creator), Lin, S.-J. (Creator), Sheu, S.-Y. (Creator) & Chen, C.-Y. (Creator), Cambridge Crystallographic Data Centre, 2016
DOI: 10.5517/ccz4mrg, https://doi.org/10.5517%2Fccz4mrg
Dataset
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CCDC 807649: Experimental Crystal Structure Determination
Yang, L.-M. (Creator), Chang, S.-F. (Creator), Wang, L.-H. (Creator), Lin, S.-J. (Creator), Chou, B.-H. (Creator), Lin, W.-K. (Creator) & Liu, P.-C. (Creator), Cambridge Crystallographic Data Centre, 2012
DOI: 10.5517/ccw3f6l, https://doi.org/10.5517%2Fccw3f6l
Dataset
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CCDC 2017519: Experimental Crystal Structure Determination
Chang, S.-F. (Contributor), Liu, H.-L. (Contributor), Ho, Y. (Contributor), Yang, L.-M. (Contributor), Tsai, Y.-E. (Contributor), Chou, B.-H. (Contributor), Wang, S.-H. (Contributor) & Lin, S.-J. (Contributor), Cambridge Crystallographic Data Centre, 2021
DOI: 10.5517/ccdc.csd.cc25qd8l, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc25qd8l&sid=DataCite
Dataset