Projects per year
Personal profile
Education
- 2002 Ph.D. National Taiwan University
- 1994 M.S. Taipei Medical University
Experience
- 2023- Dean, College of Medical Science and Technology, Taipei Medical University
- 2020-2023 Vice Dean, College of Medical Science and Technology, Taipei Medical University
- 2019-2022 Director, Ph.D. Program in Drug Discovery and Development Industry, Taipei Medical University
- 2018- Professor, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2017- Professor, Ph.D. Program in Biotechnology Research and Development, , Taipei Medical University
- 2016-2018 Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2013-2016 Associate Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2008-2013 Assistant Professor, Department of Pharmacology, Taipei Medical University
- 2009-2013 Assistant Investigator, National Health Research Institutes
- 2007-2009 Assistant Investigator, National Taiwan University
- 2002-2007 Postdoctor, National Taiwan Universiy
- 1994-1998 Teaching Assistant, Chang-Gung University
Awards
- 2019 Single Research Project Budget Award, Taipei Medical University
Research Interests
- Drug Discovery
- Disease animal model
- Pharmacology
Related Link
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Evaluating the Mechanism and Therapeutic Potential of Dyrk1/Clk Inhibitors Modulating Mrna Splicing in Human Digestive Cancers( II )
Pan, S.-L. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Investigating Potential Biomarkers and Mechanisms of Hdac6 Inhibitors in the Treatment of Human Lung Adenocarcinoma
Pan, S.-L. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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113年度大專校院STEM領域及女性研發人才培育計畫: 「整合智慧型新藥研發跨領域女性人才培育計畫-以新藥創新創業為例」
Pan, S.-L. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › d - Ministry of Education
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新穎性DDR1抑制劑對神經膠質母細胞瘤 之效用評估與機轉分析
Pan, S.-L. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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探討高選擇性 HDAC6 抑制劑在膠質母細 胞瘤之作用機轉
Pan, S.-L. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening
Yang, C. L., Wu, Y. W., Tu, H. J., Yeh, Y. H., Lin, T. E., Sung, T. Y., Li, M. C., Yen, S. C., Hsieh, J. H., Yu, M. C., Hsieh, S. Y., Hsieh, H. P., Pan, S. L. & Hsu, K. C., 2025, (Accepted/In press) In: Advanced Science. 12, 19, 2416323.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening
Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., Jan 13 2025, In: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., Jun 2024, In: Protein Science. 33, 6, e5007.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Correction to: The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells (Cell Death & Disease, (2013), 4, 9, (e810), 10.1038/cddis.2013.330)
Chen, M. C., Chen, C. H., Wang, J. C., Tsai, A. C., Liou, J. P., Pan, S. L. & Teng, C. M., Jul 2024, In: Cell Death and Disease. 15, 7, 490.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
Tu, H. J., Chao, M. W., Lee, C. C., Peng, C. S., Wu, Y. W., Lin, T. E., Chang, Y. W., Yen, S. C., Hsu, K. C., Pan, S. L. & HuangFu, W. C., 2024, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 39, 1, 2418470.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Gene expression profiling of pancreatic cancer cell line BxPC-3 induced by PAR-2 AP
Chang, L.-H. (Contributor), Pan, S.-L. (Contributor), Lai, C.-Y. (Contributor), Tsai, A.-C. (Contributor) & Teng, C.-M. (Contributor), Gene Expression Omnibus, 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44827
Dataset
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Additional file 3 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody
HuangFu, W.-C. (Creator), Sung, T.-Y. (Creator), Lee, Y.-C. (Contributor), Pan, S.-L. (Creator), Cheng, Y.-W. (Creator), Chang, F.-L. (Creator), Wei, P.-L. (Contributor), Huang, C.-C. (Contributor), Huang, H.-L. (Contributor) & Cheng, C.-C. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.14228284.v1, https://doi.org/10.6084%2Fm9.figshare.14228284.v1
Dataset
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Additional file 2: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M.-W. (Contributor), Chang, L.-H. (Contributor), Tu, H.-J. (Contributor), Chang, C.-D. (Contributor), Lai, M.-J. (Contributor), Chen, Y.-Y. (Creator), Liou, J.-P. (Creator), Teng, C.-M. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8202887.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202887/1
Dataset
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EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody
Sung, T.-Y. (Creator), Huang, H.-L. (Contributor), Cheng, C.-C. (Creator), Chang, F.-L. (Creator), Wei, P.-L. (Contributor), Cheng, Y.-W. (Creator), Huang, C.-C. (Contributor), Lee, Y.-C. (Contributor), HuangFu, W.-C. (Creator) & Pan, S.-L. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5341486.v1, https://springernature.figshare.com/collections/EGFL6_promotes_colorectal_cancer_cell_growth_and_mobility_and_the_anti_cancer_property_of_anti-EGFL6_antibody/5341486/1
Dataset
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Additional file 1: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
Chao, M.-W. (Contributor), Chang, L.-H. (Contributor), Tu, H.-J. (Contributor), Chang, C.-D. (Contributor), Lai, M.-J. (Contributor), Chen, Y.-Y. (Creator), Liou, J.-P. (Creator), Teng, C.-M. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8202881.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202881/1
Dataset