Projects per year
Personal profile
Education
- 2004-2010 Ph.D., Biomedical Science, Chang-Gung University, Taiwan
- 1998-2000 M.S., Agricultural Chemistry, National Taiwan University
- 1994-1998 B.S., Food Science, National Taiwan Ocean University
Experience
- 2022.08- Associate Professor, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University
- 2018.02-2022.07 Assistant Professor, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University
- 2015- Medical Research fellow, Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
- 2010-2015 Postdoctoral Researcher, Biomedical Science, Chang-Gung University, Taiwan
- 2002-2004 Research assistant, Institute of Biological Chemistry, Academia Sinica, Taiwan
Research Interests
- Gene regulation
- Cancer cell biology
- Chronic inflammation"
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Collaborations and top research areas from the last five years
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Investigation into the Role of Spermine Oxidase in Contributing to the Emphysema Phenotype Induced by Pm2.5 in Patients with Chronic Obstructive Pulmonary Disease
Wu, S.-M. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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A Study into Specific Endotypes of Potential Long Non-Coding Rna-Mediated Emphysema in Copd
Wu, S.-M. (PI)
8/1/22 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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探討在分層化慢性阻塞性病患者中PM2.5引起肺氣腫表現型與潛在生物標記調節的相關性
Wu, S.-M. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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The roles of long noncoding RNAs modulation by Toll-like receptors activation in COPD
Wu, S.-M. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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The Roles of Long Noncoding Rnas Modulation by Toll-Like Receptors Activation in Copd
Wu, S.-M. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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Correction to: ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota (Molecular Medicine, (2025), 31, 1, (204), 10.1186/s10020-025-01270-x)
Liu, Y. H., Lee, Y. L., Han, C. L., Lo, Y. C., Liao, Z. A., Shih, Y. S., Lin, Y. W., Peng, S. W., Lee, K. Y., Ho, S. C., Wu, S. M., Lin, C. W., Chung, K. F., Chang, J. H. & Chuang, H. C., Dec 2025, In: Molecular Medicine. 31, 1, 248.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota
Liu, Y. H., Lee, Y. L., Han, C. L., Lo, Y. C., Liao, Z. A., Shih, Y. S., Lin, Y. W., Peng, S. W., Lee, K. Y., Ho, S. C., Wu, S. M., Lin, C. W., Chung, K. F., Chang, J. H. & Chuang, H. C., Dec 2025, In: Molecular Medicine. 31, 1, 204.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
ITIH4 attenuates acute lung injury by Fe-containing particulate matter in mice via Hippo pathway in type II alveolar epithelial cells
Laiman, V., Peng, S. W., Choridah, L., Heriyanto, D. S., Yuliani, F. S., Lee, K. Y., Lai, C. H., Chang, J. H., Lee, Y. L., Ho, S. C., Wu, S. M., Han, C. L., Lin, C. W., Chung, K. F. & Chuang, H. C., Dec 2025, In: Respiratory Research. 26, 1, 201.Research output: Contribution to journal › Article › peer-review
Open Access -
Joint effects of temperature and humidity with PM2.5 on COPD
Tran, H. M., Tsai, F. J., Wang, Y. H., Lee, K. Y., Chang, J. H., Chung, C. L., Tseng, C. H., Su, C. L., Lin, Y. C., Chen, T. T., Chen, K. Y., Ho, S. C., Yang, F. M., Wu, S. M., Chung, K. F., Ho, K. F., Chuang, K. J. & Chuang, H. C., Dec 2025, In: BMC Public Health. 25, 1, 424.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Leveraging Subjective Parameters and Biomarkers in Machine Learning Models: The Feasibility of lnc-IL7R for Managing Emphysema Progression
Chen, T. T., Cheng, T. Y., Liu, I. J., Ho, S. C., Lee, K. Y., Huang, H. T., Feng, P. H., Chen, K. Y., Luo, C. S., Tseng, C. H., Chen, Y. H., Majumdar, A., Tsai, C. Y. & Wu, S. M., May 2025, In: Diagnostics. 15, 9, 1165.Research output: Contribution to journal › Article › peer-review
Datasets
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Suppressor of variegation 3–9 homologue 1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD
Chen, T.-T. (Creator), Wu, S.-M. (Creator), Chen, K.-Y. (Creator), Tseng, C.-H. (Creator), Ho, S.-C. (Creator), Chuang, H.-C. (Creator), Feng, P.-H. (Creator), Liu, W.-T. (Creator), Han, C.-L. (Creator), Huang, E.W.-C. (Creator), Yeh, Y.-K. (Creator) & Lee, K.-Y. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5645020.v1, https://springernature.figshare.com/collections/Suppressor_of_variegation_3_9_homologue_1_impairment_and_neutrophil-skewed_systemic_inflammation_are_associated_with_comorbidities_in_COPD/5645020/1
Dataset
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Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy
Chi, H.-C. (Contributor), Yeh, C.-T. (Contributor), Tsai, M.-M. (Creator), Huang, Y.-H. (Creator), Lin, K.-H. (Contributor), Chen, S.-L. (Contributor), Wu, S.-M. (Creator), Tsai, C.-Y. (Creator), Sun, C.-P. (Creator) & Chuang, W.-Y. (Creator), Taylor & Francis, 2016
DOI: 10.6084/m9.figshare.3846507.v1, https://doi.org/10.6084%2Fm9.figshare.3846507.v1
Dataset