Projects per year
Personal profile
Education
- 2007-2013 Ph.D., Institute of Bioinformatics and Biosignal Transduction, National Cheng Kung University
- 2005-2007 M.S., Department of Pharmacology, National Cheng Kung University
- 2007-2005 B.S., School of Pharmacy, Kaohsiung Medical University
Experience
- 2024.08- Associate Professor, School of Respiratory Therapy, College of Medicine, Taipei Medical University
- 2019.08- Assistant Professor, School of Respiratory Therapy, College of Medicine, Taipei Medical University
- 2020.08-2021.07 Visiting Scholar, Cardiovascular Research Institute, University of California, San Francisco, USA
- 2014.08-2019.07 Postdoctoral Research Fellow, Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University
- 2013.08-2014.07 Pharmacist
- 2011.10-2012.10 Special Volunteer, National Institute on Drug Abuse, National Institutes of Health, U.S.A
Research Interests
- Respiratory Pharmacology
- Lung Cancer Mechanism
- Drug Development
Fingerprint
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Collaborations and top research areas from the last five years
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Investigating the Role and Mechanism of Usp24 on Pulmonary Fibrosis
Wang, S.-A. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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To investigate the role of USP24 on mitochondrial function in drug- resistant lung cancer
Wang, S.-A. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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探討USP24抑制劑的鐵依賴性死亡機制並作為癌症抗藥性與纖維化的潛力治療策略
Wang, S.-A. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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探討USP24抑制劑的鐵依賴性死亡機制並作為肝纖維化的潛力治療策略
Wang, S.-A. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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To Investigate the Role of Usp24 between Lung Cancer and Copd
Wang, S.-A. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
Research output
- 19 Article
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First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity In Vitro and In Vivo
Sharma, S., Wang, S. A., Yang, W. B., Lin, H. Y., Lai, M. J., Chen, H. C., Kao, T. Y., Hsu, F. L., Nepali, K., Hsu, T. I. & Liou, J. P., Feb 22 2024, In: Journal of Medicinal Chemistry. 67, 4, p. 2963-2985 23 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
NCI677397 targeting USP24-mediated induction of lipid peroxidation induces ferroptosis in drug-resistant cancer cells
Wang, S. A., Wu, Y. C., Yang, F. M., Hsu, F. L., Zhang, K. & Hung, J. J., 2024, In: Molecular Oncology. 18, 9, p. 2255-2276 22 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis
Cheng, W. H., Chang, P. L., Wu, Y. C., Wang, S. A., Chen, C. L., Hsu, F. L., Neoh, M. M., Lin, L. Y., Yuliani, F. S., Lin, C. H. & Chen, B. C., Jun 2024, In: Lung. 202, 3, p. 343-356 14 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy
Young, M. J., Wang, S. A., Chen, Y. C., Liu, C. Y., Hsu, K. C., Tang, S. W., Tseng, Y. L., Wang, Y. C., Lin, S. M. & Hung, J. J., May 2024, In: Cell Death and Differentiation. 31, 5, p. 574-591 18 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange
Zhang, K., Yao, E., Wang, S. A., Chuang, E., Wong, J., Minichiello, L., Schroeder, A., Eckalbar, W., Wolters, P. J. & Chuang, P. T., Jul 11 2022, In: Developmental Cell. 57, 13, p. 1566-1581.e7Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)
Datasets
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Additional file 2 of Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression
Young, M.-J. (Creator), Chen, Y.-C. (Creator), Wang, S.-A. (Creator), Chang, H.-P. (Creator), Yang, W.-B. (Creator), Lee, C.-C. (Creator), Liu, C.-Y. (Creator), Tseng, Y.-L. (Creator), Wang, Y.-C. (Creator), Sun, H. S. (Creator), Chang, W.-C. (Creator) & Hung, J.-J. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.18517662.v1, https://springernature.figshare.com/articles/figure/Additional_file_2_of_Estradiol-mediated_inhibition_of_Sp1_decreases_miR-3194-5p_expression_to_enhance_CD44_expression_during_lung_cancer_progression/18517662/1
Dataset