Projects per year
Personal profile
Education
- 1986 Ph.D. Pharmacy, The Ohio State University, USA
- 1979 M.S., Applied Chemistry, National Tsing Hua University
- 1977 B.S., Pharmacy, Taipei Medical University
Experience
- 2013- Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2013- Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, Taipei Medical University
- 2010-2013 Superintendent, School of Pharmacy, Taipei Medical University
- 2008-2010 Chief Secretary, Secretariat, Taipei Medical University
- 2004-2013 Professor, School of Pharmacy, Taipei Medical University
- 2002-2004 Professor, Master Program in School of Pharmacy, Taipei Medical University
- 1992-2002 Professor, School of Pharmacy, Taipei Medical University
- 1987-1992 Associate Professor, School of Pharmacy, Taipei Medical University
Research Interests
- Development and Applications of Pharmaceutical Excipients and Pharmaceutical Dosage forms
- Development and Characterization of Biomaterials Applied for Drug Delivery Systems and Tissue Engineering
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Development of Novel Mannose-Functionalized Covid-19 Virus-Mimicking Nanoparticles (Vmns) to Elicit Durable Antibodies and Cellular Immunity
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Studies on Development of Sars-Cov-2 Spike (S) Protein Loaded Glycosylated Plga Nanoparticles Elicit Efficient Immunogenicity in Mice by Targeting Dendritic Cells
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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微整型生醫材質產學研發中心(2/3)
7/1/21 → 6/30/22
Project: A - Government Institution › b - Ministry of Science and Technology
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以參功能抗體或雙功能抗體非共價鍵合至負載 Docetaxel 與 Pictilisib 協同組合量比之聚乙二醇化奈米載體而賦予雙標靶與阻斷功效以用於惡性與轉移性乳癌治療之療效加乘與規避耐藥性(3/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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產學合作計畫－產學研發中心計畫—微整型生醫材質產學研發中心(1/3)
7/1/20 → 6/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer
Liu, Y. H., Chen, L. C., Cheng, W. T., Wei, P. S., Hsieh, C. M., Sheu, M. T., Lin, S. Y., Ho, H. O. & Lin, H. L., Feb 2023, In: Pharmaceutics. 15, 2, 473.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel anti-tumor/anti-tumor-associated fibroblast/anti-mPEG tri-specific antibody to maximize the efficacy of mPEGylated nanomedicines against fibroblast-rich solid tumor
Chen, M., Sheu, M. T., Cheng, T. L., Roffler, S. R., Lin, S. Y., Chen, Y. J., Cheng, Y. A., Cheng, J. J., Chang, H. Y., Wu, T. Y., Kao, A. P., Ho, Y. S. & Chuang, K. H., Jan 7 2022, In: Biomaterials Science. 10, 1, p. 202-215 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy
Cheng, W. J., Chuang, K. H., Lo, Y. J., Chen, M., Chen, Y. J., Roffler, S. R., Ho, H. O., Lin, S. Y. & Sheu, M. T., Apr 2022, In: Journal of Controlled Release. 344, p. 235-248 14 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Combined Docetaxel/Pictilisib-Loaded mPEGylated Nanocarriers with Dual HER2 Targeting Antibodies for Synergistic Chemotherapy of Breast Cancer
Cheng, W. J., Lin, S. Y., Chuang, K. H., Chen, M., Ho, H. O., Chen, L. C., Hsieh, C. M. & Sheu, M. T., 2022, In: International Journal of Nanomedicine. 17, p. 5353-5374 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Glycosylation of OVA antigen-loaded PLGA nanoparticles enhances DC-targeting for cancer vaccination
Chou, P. Y., Lin, S. Y., Wu, Y. N., Shen, C. Y., Sheu, M. T. & Ho, H. O., Nov 2022, In: Journal of Controlled Release. 351, p. 970-988 19 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)
Datasets
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Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors
Chen, L. (Contributor), Lin, S. (Contributor), Sheu, M. (Contributor), Ho, Y. (Contributor), Su, C. (Contributor), Chen, M. (Contributor), Ho, H. (Contributor) & Chuang, K. (Contributor), Unknown Publisher, 2018
DOI: 10.6084/m9.figshare.6213620, https://doi.org/10.6084%2Fm9.figshare.6213620
Dataset
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Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer
Chang, C. (Contributor), Hsieh, C. (Contributor), Chen, L. (Contributor), Su, C. (Contributor), Liu, D. (Contributor), Jhan, H. (Contributor), Ho, H. (Contributor) & Sheu, M. (Contributor), Unknown Publisher, Jan 1 2018
DOI: 10.6084/m9.figshare.5908795.v1, https://tandf.figshare.com/articles/Novel_application_of_pluronic_lecithin_organogels_PLOs_for_local_delivery_of_synergistic_combination_of_docetaxel_and_cisplatin_to_improve_therapeutic_efficacy_against_ovarian_cancer/5908795/1
Dataset
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Additional file 1 of Micronized sacchachitin promotes satellite cell proliferation through TAK1-JNK-AP-1 signaling pathway predominantly by TLR2 activation
Chang, H. (Creator), Lin, C. (Contributor), Hou, C. (Contributor), Sheu, M. (Contributor) & Wu, M. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.12991844.v1, https://doi.org/10.6084%2Fm9.figshare.12991844.v1
Dataset
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Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer
Hsieh, C. (Contributor), Chen, L. (Contributor), Liu, D. (Contributor), Ho, H. (Contributor), Su, C. (Contributor), Sheu, M. (Contributor), Jhan, H. (Contributor) & Chang, C. (Contributor), Unknown Publisher, 2018
DOI: 10.6084/m9.figshare.5908795, https://doi.org/10.6084%2Fm9.figshare.5908795
Dataset
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Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors
Su, C. (Contributor), Chen, M. (Contributor), Chen, L. (Contributor), Ho, Y. (Contributor), Ho, H. (Contributor), Lin, S. (Contributor), Chuang, K. (Contributor) & Sheu, M. (Contributor), Unknown Publisher, May 2 2018
DOI: 10.6084/m9.figshare.6213620.v1, https://tandf.figshare.com/articles/Bispecific_antibodies_anti-mPEG_anti-HER2_for_active_tumor_targeting_of_docetaxel_DTX_-loaded_mPEGylated_nanocarriers_to_enhance_the_chemotherapeutic_efficacy_of_HER2-overexpressing_tumors/6213620/1
Dataset