Projects per year
Personal profile
Education
- 2000-2005 Ph.D., Graduate Institute of Medical Sciences, Taipei Medical University
- 1998-2000 M.S., School of Medical Laboratory Science and Biotechnology, Taipei Medical University
- 1994-1998 B.S., School of Medical Laboratory and Biotechnology, Chung Shan Medical University
Experience
- 2025.08- Director, School of Medical Laboratory Science and Biotechnology, Taipei Medical University
- 2025.08- Director, Ph.D. Program in Medical Biotechnology, Taipei Medical University
- 2022.08- Vice Director, Research Center of Cancer Translational Medicine, Taipei Medical University
- 2020.08- Distinguished Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2021.08-2025.07 Vice Dean, Office of Research and Development, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.02- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2013.02-2016.01 Associate Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2010.02-2013.01 Assitant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2009.11- Medical research fellow, Department of Education and Research, Wan Fang Hospital, Taipei Medical University
- 2005.09-2009.09 Postdoctoral associate, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine and Angiogenesis Research Center, National Taiwan University
Research Interests
- Molecular Oncology
- Anti-cancer Drug Development
- Translational Laboratory Science
Awards
- 2020年 台灣藥理學會李鎮源教授傑出研究獎
- 2020年 臺北醫學大學年度研究成就獎
- 2020年 臺北醫學大學國際頂尖期刊論文獎
- 2020年 臺北醫學大學研究論文傑出獎
- 2015-2018年 臺北醫學大學研究論文優良獎
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigation the Malignant Role of Histamine Receptor H1 (Hrh1) in Head and Neck Squamous Cell Carcinoma and the Potential of Targeting Hrh1 as a Therapeutic Option
Chien, M.-H. (PI)
8/1/24 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Role of the Neurotransmitter-Degrading Enzyme Maob in Clear Cell Renal Cell Carcinoma Progression and Its Potential as a Therapeutic Target
Chien, M.-H. (PI)
8/1/24 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
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Investigation the Malignant Role of Histamine Receptor H1 (Hrh1) in Head and Neck Squamous Cell Carcinoma and the Potential of Targeting Hrh1 as a Therapeutic Option
Chien, M.-H. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Role of the Neurotransmitter-Degrading Enzyme Maob in Clear Cell Renal Cell Carcinoma Progression and Its Potential as a Therapeutic Target
Chien, M.-H. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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探討乙酮醣磷酸激酶在子宮內膜癌中對於治療抗性發展之調控角色
Chien, M.-H. (PI)
1/1/24 → 12/31/24
Project: B - Project of TMU › i - Other (Funded by TMU)
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ADAM9 in tumor biology: molecular functions, clinical implications, and therapeutic targeting
Ho, K. H., Wu, C. J., Yang, Y. C. & Chien, M. H., Dec 2026, In: Cellular and Molecular Biology Letters. 31, 1, 74.Research output: Contribution to journal › Review article › peer-review
Open Access -
Combined effects of lncRNA MIR17HG polymorphisms and lifestyle-related risk factors on the development and progression of tongue squamous cell carcinoma
Yang, Y. C., Ding, Y. F., Lin, C. W., Liu, Y. F., Ho, K. H., Chang, L. C., Yang, S. F. & Chien, M. H., May 20 2026, In: Bioscience Reports. 46, 5, BSR20260002.Research output: Contribution to journal › Article › peer-review
Open Access -
Missense and Intronic Variants in HNF1A Affect Prostate Cancer Aggressiveness in Patients with Biochemical Recurrence
Tung, M. C., Lin, Y. W., Lai, C. H., Lin, C. Y., Chang, L. C., Wen, Y. C., Yang, S. F. & Chien, M. H., 2026, In: International Journal of Medical Sciences. 23, 2, p. 510-519 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A novel quinoid-based CDC25 phosphatase inhibitor against human lung adenocarcinoma across different models
Lai, T. C., Narwanti, I., Sethy, B., Tsai, C. H., Sharma, A., Chang, J. H., Liou, J. P., Liu, Y. M. & Chien, M. H., Oct 2025, In: Biomedicine and Pharmacotherapy. 191, 118470.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma
Ding, Y. F., Ho, K. H., Lee, W. J., Chen, L. H., Hsieh, F. K., Tung, M. C., Lin, S. H., Hsiao, M., Yang, S. F., Yang, Y. C. & Chien, M. H., Dec 2025, In: Cell Death and Disease. 16, 1, 191.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Citations (Scopus)
Datasets
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Additional file 1: of Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
Huang, H.-C. (Contributor), Lin, Y.-W. (Contributor), Wen, Y.-C. (Contributor), Lee, W.-J. (Contributor), Yang, Y.-C. (Contributor), Chang, J.-L. (Contributor), Chien, M.-H. (Contributor) & Hsiao, M. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.8252111.v1, https://doi.org/10.6084%2Fm9.figshare.8252111.v1
Dataset
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CCDC 783608: Experimental Crystal Structure Determination
Maiti, B. (Creator), Chanda, K. (Creator), Chien, M.-H. (Creator), Sun, C.-M. (Creator), Yellol, G. S. (Creator) & Kuo, M.-L. (Creator), Cambridge Crystallographic Data Centre, 2011
DOI: 10.5517/ccv9dp6, https://doi.org/10.5517%2Fccv9dp6
Dataset
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Additional file 1 of Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma
Tung, M.-C. (Contributor), Lai, T.-C. (Contributor), Chien, M.-H. (Creator), Chen, M.-H. (Creator), Yang, Y.-C. (Contributor), Yeh, C.-N. (Creator), Jan, Y.-H. (Creator), Chang, W.-M. (Creator), Jung, S.-M. (Contributor) & Hsiao, M. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.14471532.v1, https://doi.org/10.6084%2Fm9.figshare.14471532.v1
Dataset
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Additional file 2 of Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma
Chen, M.-H. (Creator), Chang, W.-M. (Creator), Jung, S.-M. (Contributor), Yeh, C.-N. (Creator), Tung, M.-C. (Contributor), Chien, M.-H. (Creator), Jan, Y.-H. (Creator), Yang, Y.-C. (Contributor), Hsiao, M. (Creator) & Lai, T.-C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.14471535.v1, https://doi.org/10.6084%2Fm9.figshare.14471535.v1
Dataset
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Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
Wu, S.-Y. (Contributor), Wen, Y.-C. (Contributor), Ku, C.-C. (Creator), Yang, Y.-C. (Contributor), Chow, J.-M. (Contributor), Yang, S.-F. (Contributor), Lee, W.-J. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4650602.v1, https://springernature.figshare.com/collections/Penfluridol_triggers_cytoprotective_autophagy_and_cellular_apoptosis_through_ROS_induction_and_activation_of_the_PP2A-modulated_MAPK_pathway_in_acute_myeloid_leukemia_with_different_FLT3_statuses/4650602/1
Dataset