Projects per year
Personal profile
Education
- 2000-2005 Ph.D., Graduate Institute of Medical Sciences, Taipei Medical University
- 1998-2000 M.S., School of Medical Laboratory Science and Biotechnology, Taipei Medical University
- 1994-1998 B.S., School of Medical Laboratory and Biotechnology, Chung Shan Medical University
Experience
- 2022.08- Vice Director, Research Center of Cancer Translational Medicine, Taipei Medical University
- 2021.08- Vice Dean, Office of Research and Development, Taipei Medical University
- 2020.08- Distinguished Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.02- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2013.02-2016.01 Associate Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2010.02-2013.01 Assitant Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2009.11- Medical research fellow, Department of Education and Research, Wan Fang Hospital, Taipei Medical University
- 2005.09-2009.09 Postdoctoral associate, Laboratory of Molecular and Cellular Toxicology, Institute of Toxicology, College of Medicine and Angiogenesis Research Center, National Taiwan University
Research Interests
- Molecular Oncology
- Anti-cancer Drug Development
- Translational Laboratory Science
Awards
- 2020年 台灣藥理學會李鎮源教授傑出研究獎
- 2020年 臺北醫學大學年度研究成就獎
- 2020年 臺北醫學大學國際頂尖期刊論文獎
- 2020年 臺北醫學大學研究論文傑出獎
- 2015-2018年 臺北醫學大學研究論文優良獎
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Investigation the Malignant Role of Histamine Receptor H1 (Hrh1) in Head and Neck Squamous Cell Carcinoma and the Potential of Targeting Hrh1 as a Therapeutic Option
Chien, M.-H. (PI)
8/1/24 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Role of the Neurotransmitter-Degrading Enzyme Maob in Clear Cell Renal Cell Carcinoma Progression and Its Potential as a Therapeutic Target
Chien, M.-H. (PI)
8/1/24 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
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探討乙酮醣磷酸激酶在子宮內膜癌中對於治療抗性發展之調控角色
Chien, M.-H. (PI)
1/1/24 → 12/31/24
Project: B - Project of TMU › i - Other (Funded by TMU)
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Investigation the Malignant Role of Histamine Receptor H1 (Hrh1) in Head and Neck Squamous Cell Carcinoma and the Potential of Targeting Hrh1 as a Therapeutic Option
Chien, M.-H. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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探討醣蛋白ESM1在腸胃道癌症進程之角色及相關調控機制
Chien, M.-H. (PI)
1/1/23 → 12/31/23
Project: B - Project of TMU › i - Other (Funded by TMU)
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Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma
Chien, M. H., Yang, Y. C., Ho, K. H., Ding, Y. F., Chen, L. H., Chiu, W. K., Chen, J. Q., Tung, M. C., Hsiao, M. & Lee, W. J., Jan 2024, In: Cell Death and Disease. 15, 1, 82.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
ESM1 facilitates the EGFR/HER3-triggered epithelial-to-mesenchymal transition and progression of gastric cancer via modulating interplay between Akt and angiopoietin-2 signaling
Yang, Y. C., Ho, K. H., Pan, K. F., Hua, K. T., Tung, M. C., Ku, C. C., Chen, J. Q., Hsiao, M., Chen, C. L., Lee, W. J. & Chien, M. H., 2024, In: International Journal of Biological Sciences. 20, 12, p. 4819-4837 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
MAOB expression correlates with a favourable prognosis in prostate cancer, and its genetic variants are associated with the metastasis of the disease
Huang, H. C., Hsieh, Y. H., Hsiao, C. H., Lin, C. Y., Wang, S. S., Ho, K. H., Chang, L. C., Huang, H. M., Yang, S. F. & Chien, M. H., Apr 2024, In: Journal of Cellular and Molecular Medicine. 28, 8, e18229.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Roles of K(H)SRP in modulating gene transcription throughout cancer progression: Insights from cellular studies to clinical perspectives
Yang, Y. C., Ho, K. H., Hua, K. T. & Chien, M. H., Nov 2024, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1879, 6, 189202.Research output: Contribution to journal › Review article › peer-review
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The oncogenic ADAMTS1–VCAN–EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma
Wen, Y. C., Lin, Y. W., Ho, K. H., Yang, Y. C., Lai, F. R., Chu, C. Y., Chen, J. Q., Lee, W. J. & Chien, M. H., Dec 2024, In: Cellular and Molecular Biology Letters. 29, 1, 126.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
Chien, M.-H. (Contributor), Lin, Y.-W. (Contributor), Wen, Y.-C. (Contributor), Yang, Y.-C. (Contributor), Hsiao, M. (Creator), Chang, J.-L. (Contributor), Huang, H.-C. (Contributor) & Lee, W.-J. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4535717.v1, https://doi.org/10.6084%2Fm9.figshare.c.4535717.v1
Dataset
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Additional file 1 of Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma
Tung, M.-C. (Contributor), Lai, T.-C. (Contributor), Chien, M.-H. (Creator), Chen, M.-H. (Creator), Yang, Y.-C. (Contributor), Yeh, C.-N. (Creator), Jan, Y.-H. (Creator), Chang, W.-M. (Creator), Jung, S.-M. (Contributor) & Hsiao, M. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.14471532.v1, https://doi.org/10.6084%2Fm9.figshare.14471532.v1
Dataset
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Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma
Chien, M.-H. (Creator), Hsiao, M. (Creator), Jan, Y.-H. (Creator), Yang, Y.-C. (Contributor), Chang, W.-M. (Creator), Yeh, C.-N. (Creator), Jung, S.-M. (Contributor), Chen, M.-H. (Creator), Tung, M.-C. (Contributor) & Lai, T.-C. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5399457.v1, https://doi.org/10.6084%2Fm9.figshare.c.5399457.v1
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J.-M. (Contributor), Hsieh, Y.-H. (Contributor), Chen, C.-K. (Contributor), Lee, W.-J. (Contributor), Hsieh, F.-K. (Contributor), Yu, N.-Y. (Contributor), Chou, M.-C. (Contributor), Cheng, C.-W. (Contributor), Yang, S.-F. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2015
DOI: 10.6084/m9.figshare.1568934.v2, https://figshare.com/articles/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/2
Dataset
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Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1
Chao, R. (Contributor), Chow, J.-M. (Contributor), Hsieh, Y.-H. (Contributor), Chen, C.-K. (Contributor), Lee, W.-J. (Contributor), Hsieh, F.-K. (Contributor), Yu, N.-Y. (Contributor), Chou, M.-C. (Contributor), Cheng, C.-W. (Contributor), Yang, S.-F. (Contributor) & Chien, M.-H. (Contributor), Figshare, 2015
DOI: 10.6084/m9.figshare.1568934.v3, https://figshare.com/articles/Tricetin_suppresses_the_migration_invasion_of_human_glioblastoma_multiforme_cells_by_inhibiting_matrix_metalloproteinase_2_through_modulation_of_the_expression_and_transcriptional_activity_of_specificity_protein_1/1568934/3
Dataset