Pharmacology, Toxicology and Pharmaceutical Science
Histone Deacetylase Inhibitor
100%
IC50
98%
Malignant Neoplasm
78%
Histone Deacetylase 6
74%
Tubulin
56%
Antiproliferative Activity
53%
Histone Deacetylase
49%
Hydroxamic Acid
45%
Anticarcinogen
44%
Glioblastoma
38%
Vorinostat
35%
Colorectal Cancer
34%
Tumor Growth
29%
Benzamide Derivative
25%
Antitumor Activity
23%
Benzamide
22%
Biological Activity
22%
Colchicine
21%
Lung Cancer
20%
Multiple Myeloma
20%
Indole
20%
Histone Deacetylase 1
20%
Indole Derivative
19%
Prostate Cancer
19%
Structure Activity Relationship
17%
Cytotoxicity
16%
Cytokine
15%
Binding Site
15%
Lead Compound
14%
Neoplasm
14%
Pruritus
12%
Pharmaceutical Chemistry
12%
Quinoline Derivative
12%
1,4 Naphthoquinone
12%
STAT3 Protein
12%
Sulfonyl
12%
Leukemia
12%
Ligase
12%
Mouse
12%
Caspase
12%
Non Small Cell Lung Cancer
11%
Amino Acid
11%
Vincristine
11%
Heat Shock Protein 90
10%
Colorectal Carcinoma
10%
Epidermal Growth Factor Receptor
9%
Heat Shock Protein 90 Inhibitor
9%
B Cell Lymphoma
9%
Vascular Targeting Agent
9%
Tucidinostat
8%
Medicine and Dentistry
Histone Deacetylase
23%
Histone Deacetylase Inhibitor
22%
In Vitro
21%
Antineoplastic Activity
19%
Antiproliferative Activity
19%
IC50
17%
Cancer Cell
15%
Xenograft
15%
Microtubule Assembly
15%
Tubulin
15%
Benzamide Derivative
12%
Sulfonyl
12%
STAT3 Protein
12%
Programmed Cell Death
10%
HDAC1
10%
Vorinostat
9%
B-Cell Lymphoma
9%
Microtubule
9%
Cancer Cell Line
9%
Tumor Progression
8%
Multiple Myeloma
8%
Anticarcinogen
8%
Amino Acid
7%
Cell Cycle M Phase
7%
Malignant Neoplasm
7%
1,4 Naphthoquinone
6%
Anilide
6%
Tucidinostat
6%
Tissue Inhibitor of Metalloproteinase 3
6%
Cytokine Release
6%
Biological Activity
6%
4 Iodo 2,5 Dimethoxyamphetamine
6%
Colorectal Cancer
6%
Upregulation
6%
Tumor Angiogenesis
6%
Indole Derivative
6%
Pruritus
6%
Vascular-Targeting Agent
6%
Capillary
6%
Glioblastoma
6%
Ligase
6%
Cell Death
6%
Organoid
6%
Colorectal Carcinoma
6%
Prostate Cancer
6%
Docetaxel
6%
Cancer Therapy
6%
Cell Cycle Arrest
5%
Gene Expression
5%
Biochemistry, Genetics and Molecular Biology
IC50
28%
HDAC6
23%
Histone Deacetylase
22%
Anticancer
16%
Cancer Cell
12%
Isoform
10%
Antineoplastic Activity
8%
Tubulin
8%
Microtubule Assembly
8%
Caspase
8%
Cytotoxicity
8%
Mitosis Inhibition
6%
Dynamics
6%
Antiproliferative Activity
6%
Cell Cycle M Phase
6%
EZH2
6%
Mitochondrial Membrane Potential
6%
Structure Activity Relation
6%
Cell Viability
6%
T Cell
6%
Drug Resistance
6%
Tumor Necrosis Factor
6%
B Cell
6%
GI50
5%
Binding Site
5%
G1 Phase
5%
