Projects per year
Personal profile
Education
- 2006 Ph.D. (Phrmaceutical Science), National Taiwan University
- 1993 M.S.,(Pharmacy) , National Taiwan University
- 1991 B.S., School of Pharmacy, Taipei Medical University
Experience
- 2012- Associate Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2016-2019 Director, Department of Pharmaceutical Sciences, Taipei Medical University
- 2012-2012 Assistant Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2007-2012 Assistant Professor, School of Pharmacy, Taipei Medical University
- 2007-2012 Assistant Professor, Graduate Institute of Medical Sciences, Taipei Medical University
- 2004-2007 Assistant Professor, Department of Biochemistry, Taipei Medical University
- 1998-2004 Lecturer, Department of Biochemistry and Molecular Cell Biology, Taipei Medical University
- 1995-1998 Executive Officer, Department of Biochemistry and Molecular Cell Biology, Taipei Medical University
Research Interests
- Discovery and Development of small molecules
- Structure optimization through rational drug design
- Isolation and modification of natural products
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 11 Finished
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113年度「藥品品質規範國際協和化」委託辦理計畫分項計畫二：原料藥及賦形劑品質規範國際協和化
Lin, M.-H. (PI)
1/1/24 → 12/31/24
Project: A - Government Institution › c - Ministry of Health and Welfare
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「112年度「藥品品質規範國際協和化」委託辦理計畫」之「分項計畫二：原料藥及賦形劑品質規範國際協和化」
Lin, M.-H. (PI)
1/16/23 → 12/31/23
Project: A - Government Institution › c - Ministry of Health and Welfare
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111年度「導入國際化藥品品質規範與技術方法」委託辦理計畫分項二：國際化藥品品質規範之建構
Lin, M.-H. (PI)
4/18/22 → 12/31/22
Project: A - Government Institution › c - Ministry of Health and Welfare
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新興影響精神活性物質流行趨勢分析、標準品合成及圖譜建立
Lin, M.-H. (PI)
1/1/21 → 12/31/21
Project: A - Government Institution › c - Ministry of Health and Welfare
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109年度「藥品品質分析檢驗方法現代化」委託辦理計畫
Lin, M.-H. (PI)
5/20/20 → 12/20/20
Project: A - Government Institution › c - Ministry of Health and Welfare
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Discovery and biological evaluation of potent 2-trifluoromethyl acrylamide warhead-containing inhibitors of protein disulfide isomerase
Chu, J. C., Tsai, K. C., Wang, T. Y., Chen, T. Y., Tsai, J. Y., Lee, T., Lin, M. H., Hsieh, Y. S. Y., Wu, C. C. & Huang, W. J., Feb 5 2025, In: European Journal of Medicinal Chemistry. 283, 117169.Research output: Contribution to journal › Article › peer-review
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Melatonin increases Olaparib sensitivity and suppresses cancer-associated fibroblast infiltration via suppressing the LAMB3-CXCL2 axis in TNBC
Lai, Y. W., Liu, Z. W., Lin, M. H., Yang, C. C., Chu, C. Y., Chung, C. H. & Lin, C. W., Nov 2024, In: Pharmacological Research. 209, 107429.Research output: Contribution to journal › Article › peer-review
Open Access -
Design, Structure–Activity Relationships, and Enzyme Kinetic Studies of Tricyclic and Tetracyclic Coumarin–based Sulfamates as Steroid Sulfatase Inhibitors
Chiu, P.-F., Lin, I.-C., Lu, Y.-L., Chang, C.-N., Chan, H.-Y., Lin, T.-S., Tsai, K.-C., S. Y. Hsieh, Y., Chen, M.-J., Lin, M.-H. & Liang, P.-H., Sept 2023, In: Bioorganic Chemistry. 138, 106581.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Preclinical Therapeutic Assessment of a New Chemotherapeutics [Dichloro(4,4’-Bis(2,2,3,3-Tetrafluoropropoxy) Methyl)-2,2’-Bipryridine) Platinum] in an Orthotopic Patient-Derived Xenograft Model of Triple-Negative Breast Cancers
Kan, T. C., Lin, M. H., Cheng, C. C., Lu, J. W., Sheu, M. T., Ho, Y. S., Rahayu, S. & Chang, J., Apr 2022, In: Pharmaceutics. 14, 4, 839.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
The Design, Structure–Activity, and kinetic studies of 3-Benzyl-5-oxa-1,2,3,4-Tetrahydro-2H-chromeno-(3,4-c)pyridin-8-yl sulfamates as Steroid sulfatase inhibitors
Chang, C.-N., Lin, I.-C., Lin, T.-S., Chiu, P.-F., Lu, Y.-L., Narwane, M., Liu, I.-C., Hng, Y., Tsai, K.-C., Lin, M.-H., S. Y. Hsieh, Y., Chen, M.-J. & Liang, P.-H., 2022, In: Bioorganic Chemistry. 129Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)
Datasets
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Additional file 1: of The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells
Tu, H.-J. (Contributor), Lin, Y.-J. (Contributor), Chao, M.-W. (Contributor), Sung, T.-Y. (Contributor), Wu, Y.-W. (Contributor), Chen, Y.-Y. (Contributor), Lin, M.-H. (Contributor), Liou, J.-P. (Contributor), Pan, S.-L. (Contributor) & Yang, C.-R. (Contributor), Unknown Publisher, Dec 29 2018
DOI: 10.6084/m9.figshare.7531874.v1, https://springernature.figshare.com/articles/Additional_file_1_of_The_anticancer_effects_of_MPT0G211_a_novel_HDAC6_inhibitor_combined_with_chemotherapeutic_agents_in_human_acute_leukemia_cells/7531874/1
Dataset
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The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells
Tu, H.-J. (Contributor), Lin, Y.-J. (Contributor), Chao, M.-W. (Contributor), Sung, T.-Y. (Creator), Wu, Y.-W. (Creator), Chen, Y.-Y. (Creator), Lin, M.-H. (Contributor), Liou, J.-P. (Creator), Pan, S.-L. (Contributor) & Yang, C.-R. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4350887.v1, https://springernature.figshare.com/collections/The_anticancer_effects_of_MPT0G211_a_novel_HDAC6_inhibitor_combined_with_chemotherapeutic_agents_in_human_acute_leukemia_cells/4350887/1
Dataset