Personal profile
Education
- 2010 Ph.D., Graduate Institute of Medicine, Kaohsiung Medical University, Taiwan
- 2005 MS, Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Taiwan
- 2004 Bachelor, Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Taiwan
Experience
- 2022- Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taiwan
- 2017-2022 Associate Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taiwan
- 2016-2017 Assistant Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2015-2017 Assistant Professor, Ph.D. Program for Translational Medicine, Taipei Medical University
- 2012-2017 Assistant Professor, Graduate Institute of Pharmacognosy, Taipei Medical University, Taiwan
- 2010-2011 Adjunct Assistant Professor, Department and Graduate of Aquaculture, National Kaohsiung Marine University, Taiwan
Awards
- 2021 科技部吳大猷先生紀念獎_藥學領域
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2020 國家新創獎_新創精進
- 2019 國家新創獎_學研新創
- 2012 戰國策創業競賽 (特優獎)
- 2008 National Innovation Award (The First Prize)
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Development of Humanized Antagonistic Bace-2 Antibody and Its Derivative Pd-L1 Fusion Protein Drug as a Novel Islet-Protective Strategy for Comprehensive Application in the Treatment of Type 1 and Type 2 Diabetes
Chuang, K.-H. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Development of Humanized Antagonistic Bace-2 Antibody and Its Derivative Pd-L1 Fusion Protein Drug as a Novel Islet-Protective Strategy for Comprehensive Application in the Treatment of Type 1 and Type 2 Diabetes
Chuang, K.-H. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Development of Humanized Antagonistic Bace-2 Antibody and Its Derivative Pd-L1 Fusion Protein Drug as a Novel Islet-Protective Strategy for Comprehensive Application in the Treatment of Type 1 and Type 2 Diabetes
Chuang, K.-H. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Development of Antagonistic Bace-2 Antibodies to Improve Type 2 Diabetes by Inducing Pancreatic Beta-Cells Proliferation( III )
Chuang, K.-H. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Development of Antagonistic Bace-2 Antibodies to Improve Type 2 Diabetes by Inducing Pancreatic Beta-Cells Proliferation( II )
Chuang, K.-H. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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A heavy-chain antibody-drug conjugate targeting glycosylated CEACAM6 inhibits brain metastatic tumor growth
Tsai, Y. T., Yen, M. H., Hu, P. J., Lee, C. C., Liu, C. Y., Cheng, T. M., Shen, H. T., Benjamin Zhang, B. X., Lee, H. L., Chuang, K. H., Yap, C. V., Wang, W. C. & Wu, M. H., Jun 28 2026, In: Cancer Letters. 648, 218463.Research output: Contribution to journal › Article › peer-review
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Short-chain dense brush PEGylation on rigid nanocarriers overcomes anti-PEG antibody recognition for immune-stealth drug delivery
Chen, T. Y., Chang, C. Y., Xu, L., Wen, T. C., Lin, Y. H., Peng, C. L., Yeh, Y. Q., Chen, C. H., Tsai, I. L., Chuang, K. H. & Wu, S. H., May 2026, In: Biomaterials. 328, 123854.Research output: Contribution to journal › Article › peer-review
3 Link opens in a new tab Citations (Scopus) -
Development of a tumor-region-selective activation monoclonal antibody targeting the 4-1BB receptor for enhanced therapeutic efficacy and safety
Liao, T. Y., Liu, Y. L., Chen, C. Y., Wu, B. T., Liu, E. S., Hong, S. T., Huang, B. C., Cheng, Y. A., Chen, M., Chuang, K. H., Lin, W. W., Chuang, C. H., Chen, F. M., Ho, K. W. & Cheng, T. L., May 2025, In: International Journal of Biological Macromolecules. 305, 141003.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Citations (Scopus) -
Melatonin reverses bisphenol A-induced toxicity in granulosa cells: Restoration of FSHR and connexin 43 expression
Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 2025, (Accepted/In press) In: Taiwanese Journal of Obstetrics and Gynecology. 64, 3, p. 469-476 8 p.Research output: Contribution to journal › Article › peer-review
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Nonshrinkable Thermosensitive Hydrogels Combined with Bispecific Anti-PSMA/CD3 T-Cell Engager for Effective Against Tumors in Mice Model
Wei, P. S., Chou, P. Y., Hsu, H. Y., Chen, M., Chen, Y. J., Tsai, T. H., Wen, B. Y., Sheu, M. T., Chuang, K. H. & Lin, H. L., 2025, In: International Journal of Nanomedicine. 20, p. 3083-3111 29 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus)
Datasets
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Additional file 1 of A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies
Wang, Y.-T. (Creator), Huang, B.-C. (Creator), Hsieh, Y.-C. (Creator), Ho, K.-W. (Creator), Cheng, T.-L. (Creator), Wang, J.-Y. (Creator), Liu, H.-J. (Creator), Tsai, H.-L. (Creator), Liao, J.-M. (Creator), Liu, Y.-L. (Creator), Hong, S.-T. (Creator), Chen, I.-J. (Creator), Su, Y.-C. (Creator) & Chuang, K.-H. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.19101789.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_A_universal_in_silico_V_D_J_recombination_strategy_for_developing_humanized_monoclonal_antibodies/19101789/1
Dataset
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A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies
Hsieh, Y.-C. (Creator), Liao, J.-M. (Creator), Chuang, K.-H. (Creator), Ho, K.-W. (Creator), Hong, S.-T. (Creator), Liu, H.-J. (Creator), Huang, B.-C. (Creator), Chen, I.-J. (Creator), Liu, Y.-L. (Creator), Wang, J.-Y. (Creator), Tsai, H.-L. (Creator), Su, Y.-C. (Creator), Wang, Y.-T. (Creator) & Cheng, T.-L. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5819661.v1, https://springernature.figshare.com/collections/A_universal_in_silico_V_D_J_recombination_strategy_for_developing_humanized_monoclonal_antibodies/5819661/1
Dataset
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Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer
Cheng, Y.-A. (Creator), Wu, T.-H. (Contributor), Wang, Y.-M. (Contributor), Cheng, T.-L. (Creator), Chen, I.-J. (Creator), Lu, Y.-C. (Contributor), Chuang, K.-H. (Contributor), Wang, C.-K. (Contributor), Chen, C.-Y. (Creator), Lin, R.-A. (Creator), Chen, H.-J. (Creator), Liao, T.-Y. (Contributor), Liu, E.-S. (Contributor) & Chen, F.-M. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5105096.v1, https://springernature.figshare.com/collections/Humanized_bispecific_antibody_mPEG_HER2_rapidly_confers_PEGylated_nanoparticles_tumor_specificity_for_multimodality_imaging_in_breast_cancer/5105096/1
Dataset
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Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors
Su, C.-Y. (Contributor), Chen, M. (Contributor), Chen, L.-C. (Contributor), Ho, Y.-S. (Contributor), Ho, H.-O. (Contributor), Lin, S.-Y. (Contributor), Chuang, K.-H. (Contributor) & Sheu, M.-T. (Contributor), Unknown Publisher, May 2 2018
DOI: 10.6084/m9.figshare.6213620.v1, https://tandf.figshare.com/articles/Bispecific_antibodies_anti-mPEG_anti-HER2_for_active_tumor_targeting_of_docetaxel_DTX_-loaded_mPEGylated_nanocarriers_to_enhance_the_chemotherapeutic_efficacy_of_HER2-overexpressing_tumors/6213620/1
Dataset
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Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors
Chen, L.-C. (Contributor), Lin, S.-Y. (Contributor), Sheu, M.-T. (Contributor), Ho, Y.-S. (Contributor), Su, C.-Y. (Contributor), Chen, M. (Contributor), Ho, H.-O. (Contributor) & Chuang, K.-H. (Contributor), Unknown Publisher, 2018
DOI: 10.6084/m9.figshare.6213620, https://doi.org/10.6084%2Fm9.figshare.6213620
Dataset