Projects per year
Personal profile
Education
- 2012 Ph.D. ISF College of Pharmacy, Punjab, India
- 2008 M.S. ISF College of Pharmacy, Punjab, India
- 2006 B.S. Rajiv Academy For Pharmacy. U.P,, India
Experience
- 2024.09 - Associate Editor, Journal of Enzyme Inhibition and Medicinal Chemistry (Taylor and Francis, Impact Factor - 5.6)
- 2023- Associate Professor, Department of Pharmaceutical Sciences, Taipei Medical UniversityTaipei Medical University
- 2019-2023 Assistant Professor, Department of Pharmaceutical Sciences, Taipei Medical University
- 2014-2019 Post-Doctoral Research Fellow, Taipei Medical University
- 2011-2014 Assistant Professor, Guru Nanak Dev University
- 2008-2011 Assistant Professor, Punjab Technical University
Awards
- Editorial Board Member, Medicinal Research Reviews (Wiley, Impact Factor - 10.9).
- Editorial board member - Mini Reviews in Medicinal chemistry (IF - 2.91, Chemistry/Medicinal)
- Plum Blossom Card (Permanent Resident Certificate) by Government of Taiwan 2020
- Outstanding Post Doctoral Fellow (Medicinal Chemistry), 2018, Taipei Medical University, Taiwan.
Project title: The use of organometallic reaction in the synthesis of anticancer agents (2/2)
- Outstanding Post Doctoral Fellow (Medicinal Chemistry), 2017, Taipei Medical University, Taiwan.
Project title: The use of organometallic reaction in the synthesis of anticancer agents
- Outstanding contribution in reviewing EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017.
- Outstanding Post Doctoral Fellow (Medicinal Chemistry), 2016, Taipei Medical University, Taiwan.
Project title: Application of regioselective substitution on 1,4- Benzoquinone derivatives to provide potent anticancer agents
- Outstanding contribution in reviewing BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, 2016.
- Outstanding Post Doctoral Fellow (Medicinal Chemistry), 2015, Taipei Medical University, Taiwan.
Project title: Preclinical development for novel HSP90 inhibitors as anticancer drugs
- Outstanding Post Doctoral Fellow (Medicinal Chemistry), 2015, Taipei Medical University, Taiwan
Project title: Development of ITCHE3 ubiquitin ligase inhibitors as anticancer drug
Research Interests
- Natural product chemistry
- Organic synthesis
- Medicinal chemistry
- Drug design
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Collaborations and top research areas from the last five years
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點擊化學及鈴木偶合反應方法建構鎖定DNA損害修復路徑之小分子雙效抑制劑(1/3)
Nepali, K. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Click Chemistry and Suzuki Coupling Approach for the Construction of Small Molecule Bifunctional Inhibitors Targeting the Dna Damage Repair Pathways.
Nepali, K. (PI)
8/1/24 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
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理性設計全新類型雙效PARP-SYK抑制劑作為抗癌試劑
Nepali, K. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Development of a retinoic-base histone deacetylase inhibitor as early-stage AMD treatment
Nepali, K. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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Structural Engineering of Biaryls, Alkaloids, Flavones and Coumarins to Furnish Anti-Fibrotic Agents for Idiopathic Pulmonary Fibrosis
Nepali, K. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Contemporary approaches to mitigating antibacterial drug resistance
Grewal, A. S., Dhingra, A. K., Nepali, K., Deswal, G. & Srivastav, A. L., Apr 1 2024, IGI Global Publishing. 384 p.Research output: Book/Report › Book
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Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress
Sharma, R., Chiang, Y. H., Chen, H. C., Lin, H. Y., Yang, W. B., Nepali, K., Lai, M. J., Chen, K. Y., Liou, J. P. & Hsu, T. I., Apr 1 2024, In: Cancer Letters. 586, 216666.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Emerging Strategies in Antibacterial Drug Resistance Management: Mechanisms, Challenges, and Novel Interventions
Grewal, A. S., Dhingra, A. K., Nepali, K., Deswal, G. & Srivastav, A. L., Oct 14 2024, Nova Science Publishers, Inc. 297 p.Research output: Book/Report › Book
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First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity In Vitro and In Vivo
Sharma, S., Wang, S. A., Yang, W. B., Lin, H. Y., Lai, M. J., Chen, H. C., Kao, T. Y., Hsu, F. L., Nepali, K., Hsu, T. I. & Liou, J. P., Feb 22 2024, In: Journal of Medicinal Chemistry. 67, 4, p. 2963-2985 23 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Frontiers in combating antibacterial resistance: Current perspectives and future Horizons
Grewal, A. S., Dhingra, A. K., Nepali, K., Deswal, G. & Srivastav, A. L., Mar 25 2024, IGI Global Publishing. 422 p.Research output: Book/Report › Book
Datasets
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Design, synthesis and evaluation of 2,4-diarylpyrano[3,2-c]chromen-5(4H)-one as a new class of non-purine xanthine oxidase inhibitors
Virdi, H. S. (Creator), Sharma, S. (Contributor), Mehndiratta, S. (Creator), Bedi, P. M. S. (Contributor) & Nepali, K. (Contributor), Figshare, 2015
DOI: 10.6084/m9.figshare.1568378.v1, https://figshare.com/articles/Design_synthesis_and_evaluation_of_2_4_diarylpyrano_3_2_c_chromen_5_4H_one_as_a_new_class_of_non_purine_xanthine_oxidase_inhibitors/1568378/1
Dataset