Projects per year
Personal profile
Education
- 2009 Ph.D. Institute of Basic Medical Sciences, National Cheng Kung University
- 2004 MS. Institute of Biomedical Sciences, National Sun Yat-sen University
- 2002 B.S. Department of Marine Biotechnology and Resources, National Sun Yat-sen University
Experience
- 2022- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2022- Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018-2024.07 Director, Master Program in Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2017- Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2023.03.14-2024.03.13 Director, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2016-2022 Associate Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2018-2022 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University
- 2012 Assistant Research Fellow, Institute for Cancer Biology and Drug Discovery, Taipei Medical University
- 2010-2012 Postdoctoral Fellow in Division of Medicinal Chemistry, Ohio State University, USA
Awards
- 2009 National Cheng Kung University College of Medicine-Award of Excellent Paper
Research Interests
- Signal transduction of tumor biology
- Drug repurposing of cancer
- The roles of miRNAs in cancer
Related Link
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigation the Expression Prolife and Functional Role of Early Metastasis of Pancreatic Cancer-Associated Gene-Fxyd3 in Regulating of Metastasis and Acidic Microenvironment through Mir31hg-Mir-7-5p/Mir-206-Fxyd3 Axis( III )
Lee, K.-H. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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探討Drug Tolerant Persister細胞在大腸癌5-Fluorouracil化療藥抗藥性中的角色
Lee, K.-H. (PI)
7/1/25 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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113年度產學合作計畫-早發性大腸直腸癌精準治療策略：建立藥物基因體學之老藥新用模式並結合磷脂促翻轉酶新穎性抗體藥物
Lee, K.-H. (PI)
11/1/24 → 10/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Early-Onset Colorectal Cancer Precision Treatment Strategy: Establishing Drug Repurposing Approach Based on Pharmacogenomics and Combining Novel Anoctamin-6 Neutralizing Antibody
Lee, K.-H. (PI)
11/1/24 → 10/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Investigation the Expression Prolife and Functional Role of Early Metastasis of Pancreatic Cancer-Associated Gene-Fxyd3 in Regulating of Metastasis and Acidic Microenvironment through Mir31hg-Mir-7-5p/Mir-206-Fxyd3 Axis(2/3)
Lee, K.-H. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Transcriptome analyses identify 10 deregulated hub genes and essential molecular mechanisms in early-onset colorectal cancer
Nguyen, H. D., Chen, M. J., Lee, C. Y., Ni, Y. C., Yee, K. X., Wu, Y. F. & Lee, K. H., 2025, In: Frontiers in Oncology. 15, 1655143.Research output: Contribution to journal › Article › peer-review
Open Access -
Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function
Chen, C. H., Lin, H. W., Huang, M. F., Chiang, C. W., Lee, K. H., Phuong, N. T., Cai, Z. Y., Chang, W. C. & Lin, D. Y., Dec 2024, In: BMC Molecular and Cell Biology. 25, 1, 2.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Association of diabetes mellitus with early-onset colorectal cancer: A systematic review and meta-analysis of 19 studies including 10 million individuals and 30,000 events
Khoa Ta, H. D., Nguyen, N. N., Ho, D. K. N., Nguyen, H. D., Ni, Y.-C., Yee, K. X., Pan, S.-R., Nguyen, H. S., Thai Hoang Phuoc, T., Chen, M.-J. & Lee, K.-H., Aug 17 2023, In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 17, 8, p. 102828Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer
Lin, C. H., Lin, W. D., Huang, Y. C., Chen, Y. C., Loh, Z. J., Ger, L. P., Lin, F. C., Li, H. Y., Cheng, H. C., Lee, K. H., Hsiao, M. & Lu, P. J., Mar 2023, (Accepted/In press) In: Cancer Gene Therapy. 30, 3, p. 404-413 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Correction to: Hydroxychloroquine (HCQ) Modulates Autophagy and Oxidative DNA Damage Stress in Hepatocellular Carcinoma to Overcome Sorafenib Resistance via TLR9/SOD1/hsa-miR-30a-5p/Beclin-1 Axis (Cancers, (2021), 13, 13, (3227), 10.3390/cancers13133227)
Chen, M. Y., Yadav, V. K., Chu, Y. C., Ong, J. R., Huang, T. Y., Lee, K. F., Lee, K. H., Yeh, C. T. & Lee, W. H., Feb 2023, In: Cancers. 15, 4, 1028.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Citation (Scopus)
Datasets
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, K.-H. (Creator), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor), Chang, W.-C. (Creator), Shen, C.-K. J. (Contributor), Kao, T.-J. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Huang, W.-C. (Contributor) & Lin, H.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://doi.org/10.6084%2Fm9.figshare.7313777.v1
Dataset
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Additional file 2: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y.-C. (Creator), Lee, K.-H. (Creator), Shen, C.-K. J. (Contributor), Chang, W.-C. (Creator), Lin, J.-H. (Contributor), Huang, W.-C. (Contributor), Lin, H.-C. (Contributor), Lin, H.-C. (Contributor), Kao, T.-J. (Contributor) & Huang, C.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313798.v1, https://doi.org/10.6084%2Fm9.figshare.7313798.v1
Dataset
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Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y.-C. (Creator), Huang, W.-C. (Contributor), Lin, J.-H. (Contributor), Kao, T.-J. (Contributor), Lin, H.-C. (Contributor), Lee, K.-H. (Creator), Lin, H.-C. (Contributor), Shen, C.-K. J. (Contributor), Chang, W.-C. (Creator) & Huang, C.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.c.4294289.v1, https://doi.org/10.6084%2Fm9.figshare.c.4294289.v1
Dataset
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Additional file 3: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Shen, C.-K. J. (Contributor), Lin, H.-C. (Contributor), Lee, K.-H. (Creator), Huang, W.-C. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Kao, T.-J. (Contributor), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor) & Chang, W.-C. (Creator), Figshare, 2018
DOI: 10.6084/m9.figshare.7313816.v1, https://doi.org/10.6084%2Fm9.figshare.7313816.v1
Dataset