Kuang-tai Kuo

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Emailktkuotmu.edutw

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Research activity per year

Education

2005-2011 Ph.D., Institute of Clinical Medicine, National Yang-Ming University
1990-1997 M.D., School of Medicine , National Taiwan University

Experience

2025.08- Chairperson, Taipei Cancer Center, Taipei Medical University
2024.07-2024.08 Acting Director, Division of Pediatric Surgery, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
2024.02- Director, Department of Surgery, School of Medicine, Taipei Medical University
2022.12-2024.10 Director, Division of Cardiology, Department of Internal Medicine, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
2022.08- Professor, Department of Surgery, School of Medicine, Taipei Medical University
2022.08- Associate Director, Research Center of Organ Transplant, Taipei Medical University
2021.11-2025.07 Director, Department of Surgery, Taipei Medical University Shuang Ho Hospital
2020.03- Director, Division of Chest Surgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University
2019.02-2022.07 Associate Professor, Department of Surgery, School of Medicine, Taipei Medical University
Attending Physician, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
Director, Division of Thoracic Surgery, Department of Surgery, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
2014 Visiting Scholar, Kyoto University Hospital
2013 Visiting Scholar, Duke University Medical Center
2012.11-2019.01 Assistant Professor, Department of Surgery, School of Medicine, Taipei Medical University
2004.11-2010.05 Attending Physician, Taipei Tzu Chi Hospital
2003.10-2004.09 Attending Physician, Lotung Poh-Ai Hospital
1999.07-2003.09 Chief Resident Physician, Taipei Veterans General Hospital
1998.07-1999.06 Resident Physician, Linkou Chang Gung Memorial Hospital
1997.07-1998.06 Resident Physician, Taipei Hospital, Ministry of Health and Welfare

Awards

2014-2016 NSC project
2012-2013 NSC project
2008-2009 NSC project
2006-2007 NSC project

Research Interests

Thoracic Surgery
Surgical Oncology
Lung Transplantation
Molecular Biology
Tumor Metastasis

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Dive into the research topics where Kuang-tai Kuo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

1 Similar Profiles

2 Active
10 Finished

Targeting Eya2-Tead4-Oma1 Axis Regulates Mitochondrial Activity to Overcome the Therapy Resistance in Drug Tolerant Persister Lung Cancer Cells
Kuo, K.-T. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
Targeting Eya2-Tead4-Oma1 Axis Regulates Mitochondrial Activity to Overcome the Therapy Resistance in Drug Tolerant Persister Lung Cancer Cells
Kuo, K.-T. (PI)
8/1/23 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
Targeting Eya2-Tead4-Oma1 Axis Regulates Mitochondrial Activity to Overcome the Therapy Resistance in Drug Tolerant Persister Lung Cancer Cells
Kuo, K.-T. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
Seeking a Novel Therapeutic Strategy of Eya2/Brd4 Axis for the Treatment of Non-Small Cell Lung Cancer: Therapy for Drug Tolerant Persister Cells
Kuo, K.-T. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
Targeting the Btk-Itk Axis as a Potential Therapeutic Strategy for Overcoming Drug Resistance and Inhibiting Brain Metastasis in Lung Cancer
Kuo, K.-T. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council

Drug-tolerant persister cells in head and neck squamous cell carcinoma: Molecular mechanisms and therapeutic opportunities
Ling, H. H., Huang, H. Y., Huang, C. M., Yasir, M., Ko, C. C., Yadav, V. K., Kuo, K. T., Yeh, C. T. & Tsai, J. T., Jan 2026, In: Translational Oncology. 63, 102579.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Link opens in a new tab Citation (Scopus)
Gluteal adipose-derived stem cell exosomes promote macrophage polarization and cartilage regeneration in osteoarthritis via PTPRC modulation
Chen, K. T., Huang, C. C., Yadav, V. K., Pikatan, N. W., Fong, I. H., Kuo, K. T. & Chiu, Y. S., Mar 2026, In: Biomedicine and Pharmacotherapy. 196, 119130.
Research output: Contribution to journal › Article › peer-review

Open Access
NMN-primed exosomes derived from infrapatellar fat pad mesenchymal stem cells exert synergistic anti-inflammatory and cartilage-protective effects via MERTK pathway activation in knee osteoarthritis
Chen, K. T., Huang, C. C., Yadav, V. K., Pikatan, N. W., Fong, I. H., Kuo, K. T. & Chiu, Y. S., Jan 5 2026, In: International Journal of Pharmaceutics. 687, 126367.
Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Citations (Scopus)
Redox-driven FABP1/PPARγ signaling fuels peroxisomal fatty acid oxidation and confers cetuximab resistance in drug-tolerant head and neck cancer cells
Ling, H. H., Huang, C. S., Hsieh, M. S., Yadav, V. K., Fong, I. H., Kuo, K. T., Yeh, C. T. & Tsai, J. T., Mar 16 2026, In: Free Radical Biology and Medicine. 246, p. 209-222 14 p.
Research output: Contribution to journal › Article › peer-review
RHOJ-induced chemotherapy resistance through epithelial–mesenchymal transition in drug-tolerant persister cells of head and neck cancer
Ling, H. H., Huang, C. M., Hsieh, M. S., Yadav, V. K., Fong, I. H., Kuo, K. T., Yeh, C. T. & Tsai, J. T., Mar 2026, In: Translational Oncology. 65, 102673.
Research output: Contribution to journal › Article › peer-review

Open Access

Additional file 3: of Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
Kuo, K.-T. (Contributor), Huang, W.-C. (Contributor), Bamodu, O. (Contributor), Lee, W.-H. (Contributor), Wang, C.-H. (Contributor), Hsiao, M. (Contributor), Wang, L.-S. (Contributor) & Yeh, C.-T. (Contributor), Unknown Publisher, Aug 9 2018
DOI: 10.6084/m9.figshare.6953543.v1, https://springernature.figshare.com/articles/Additional_file_3_of_Histone_demethylase_JARID1B_KDM5B_promotes_aggressiveness_of_non-small_cell_lung_cancer_and_serves_as_a_good_prognostic_predictor/6953543/1
Dataset
Additional file 3: of Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway
Huang, W.-C. (Contributor), Kuo, K.-T. (Contributor), Wang, C.-H. (Contributor), Yeh, C.-T. (Contributor) & Wang, Y. (Contributor), Unknown Publisher, Jan 1 2019
DOI: 10.6084/m9.figshare.8057546.v1, https://springernature.figshare.com/articles/Additional_file_3_of_Cisplatin_resistant_lung_cancer_cells_promoted_M2_polarization_of_tumor-associated_macrophages_via_the_Src_CD155_MIF_functional_pathway/8057546/1
Dataset
Additional file 2: of Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
Kuo, K.-T. (Contributor), Huang, W.-C. (Contributor), Bamodu, O. (Contributor), Lee, W.-H. (Contributor), Wang, C.-H. (Contributor), Hsiao, M. (Contributor), Wang, L.-S. (Contributor) & Yeh, C.-T. (Contributor), Unknown Publisher, Aug 9 2018
DOI: 10.6084/m9.figshare.6953528.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Histone_demethylase_JARID1B_KDM5B_promotes_aggressiveness_of_non-small_cell_lung_cancer_and_serves_as_a_good_prognostic_predictor/6953528/1
Dataset
Additional file 1: of Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway
Huang, W.-C. (Contributor), Kuo, K.-T. (Contributor), Wang, C.-H. (Contributor), Yeh, C.-T. (Contributor) & Wang, Y. (Contributor), Unknown Publisher, Jan 1 2019
DOI: 10.6084/m9.figshare.8057528.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Cisplatin_resistant_lung_cancer_cells_promoted_M2_polarization_of_tumor-associated_macrophages_via_the_Src_CD155_MIF_functional_pathway/8057528/1
Dataset
Additional file 2: of Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway
Huang, W.-C. (Contributor), Kuo, K.-T. (Contributor), Wang, C.-H. (Contributor), Yeh, C.-T. (Contributor) & Wang, Y. (Contributor), Unknown Publisher, Jan 1 2019
DOI: 10.6084/m9.figshare.8057534.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Cisplatin_resistant_lung_cancer_cells_promoted_M2_polarization_of_tumor-associated_macrophages_via_the_Src_CD155_MIF_functional_pathway/8057534/1
Dataset

Kuang-tai Kuo

Personal profile

Education

Experience

Awards

Research Interests

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Targeting Eya2-Tead4-Oma1 Axis Regulates Mitochondrial Activity to Overcome the Therapy Resistance in Drug Tolerant Persister Lung Cancer Cells

Targeting Eya2-Tead4-Oma1 Axis Regulates Mitochondrial Activity to Overcome the Therapy Resistance in Drug Tolerant Persister Lung Cancer Cells

Targeting Eya2-Tead4-Oma1 Axis Regulates Mitochondrial Activity to Overcome the Therapy Resistance in Drug Tolerant Persister Lung Cancer Cells

Seeking a Novel Therapeutic Strategy of Eya2/Brd4 Axis for the Treatment of Non-Small Cell Lung Cancer: Therapy for Drug Tolerant Persister Cells

Targeting the Btk-Itk Axis as a Potential Therapeutic Strategy for Overcoming Drug Resistance and Inhibiting Brain Metastasis in Lung Cancer

Drug-tolerant persister cells in head and neck squamous cell carcinoma: Molecular mechanisms and therapeutic opportunities

Gluteal adipose-derived stem cell exosomes promote macrophage polarization and cartilage regeneration in osteoarthritis via PTPRC modulation

NMN-primed exosomes derived from infrapatellar fat pad mesenchymal stem cells exert synergistic anti-inflammatory and cartilage-protective effects via MERTK pathway activation in knee osteoarthritis

Redox-driven FABP1/PPARγ signaling fuels peroxisomal fatty acid oxidation and confers cetuximab resistance in drug-tolerant head and neck cancer cells

RHOJ-induced chemotherapy resistance through epithelial–mesenchymal transition in drug-tolerant persister cells of head and neck cancer

Additional file 3: of Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor

Additional file 3: of Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway

Additional file 2: of Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor

Additional file 1: of Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway

Additional file 2: of Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway

Kuang-tai Kuo

Personal profile

Education

Experience

Awards

Research Interests

Fingerprint

Collaborations and top research areas from the last five years

Projects

Research output

Datasets